"Esomeprazole": cov lus qhia rau kev siv, tiag tiag counterparts

"Esomeprazole" - ib tug yeeb tshuaj uas belongs rau lub Organotropona hnyuv tshuaj. Cov tshuaj muaj antiulcer kev txiav txim thiab yog ib tug proton twj tso kua mis inhibitor.

Muaj pes tsawg leeg, qhov kev tso tawm daim ntawv "esomeprazole" tshuaj

Cov tshuaj no muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj nrog ib tug ntau npaum ntawm 20 thiab 40 mg ntawm active ingredient esomeprazole, raws li zoo raws li nyob rau hauv daim ntawv ntawm ib tug hmoov npaj rau tov rau kev txhaj tshuaj (40 mg vial). Coated ntsiav tshuaj, nyias mus nyias uas yuav siv sij hawm qhov chaw nyob rau hauv cov hnyuv.

Pharmacological kev txiav txim "esomeprazole" tshuaj

Yuav ua li cas yog cov tshuaj "esomeprazole"? Cov lus qhia rau kev siv qhia tau hais tias hais tias qhov no antiulcer neeg sawv cev, uas, ua ib tug tsis muaj zog puag, tau txais lub active daim ntawv tom qab haus. "Esomeprazole" cheeb qhov uas cov enzyme H ⁺ -K ⁺ -ATPase kev ua si, thiab secretion ntawm hydrochloric acid (tsa, basal). Tsim nyog txiav txim tshwm sim tsis pub dhau ib teev tom qab haus ntawm cov tshuaj. Thaum tau txais "esomeprazole" ua txhua txhua hnub, rau tsib hnub, lub pub txhua txhua hnub koob tshuaj - 20 mg tom qab stimulation los ntawm pentagastrin qib siab tshaj plaws ntawm hydrochloric acid yog txo tshuam (txog 90%).

tshuaj

"Esomeprazole" cov lus qhia rau kev siv yog raws li ib tug yeeb tshuaj uas, penetrating hauv lub cev, sai thiab zoo absorbed, binds rau cov nqaijrog zoo 100% (97%). Lub bioavailability ntau zog rau kev rov siv cov tshuaj los ntawm 64 mus 89%. Lub medicament yuav siv sij hawm rau hauv daim ntawv ntawm metabolites thiab tas feem ntau nyob rau hauv cov zis, ib tug me nyuam feem los ntawm tam sim no nyob rau hauv cov quav.

Indications "esomeprazole" npaj

"Esomeprazole" analogues siv nyob rau hauv cov neeg mob uas Gastroesophageal reflux kab mob kev kho mob thiab relapse kev tiv thaiv. Lub cuab tam siv nyob rau hauv cov kev kho mob ntawm ulcers ntawm lub plab los sis duodenum, rau kev tiv thaiv kab mob uas tshwm sim taus vim narcotics yuav muab.

Cov tshuaj siv nyob rau hauv peptic rwj thaum cuam tshuam duodenum los yog lub plab. Nws yuav tsum muaj ntaub ntawv rau cov neeg mob uas tau kho esophagitis, thaum lub sij hawm heev relapse kev tiv thaiv. Permissible uake nrog cov txhais tau tias "esomeprazole" antibacterial tshuaj. Ntsiav tshuaj thiab txhaj tshuaj nyob rau hauv lub complex txoj kev kho nyob rau hauv cov ntaub ntawv no tso cai rau ua kom puas Helicobacter pylori.

Contraindications tau txais "esomeprazole" tshuaj

Contraindications muaj xws li muaj hnub nyoog tsawg tshaj li kaum ob xyoos, npau taws me ntsis rau esomeprazole, lub sij hawm ntawm kev pub niam mis. Lub txim ntawm tshuaj kho mob tsis tau tsim thaum lub sij hawm cev xeeb tub.

tshuaj pab

Lub tshuaj no yog siv nyob rau hauv ib tug txhua txhua hnub koob tshuaj 20-40 mg. Lub caij ntawm txoj kev kho yog txiav txim indications regimen thiab txais tos efficiency medicament "esomeprazole". Ntsiav tshuaj thiab nyuaj ntws daws nyob rau raum insufficiency siv ib tug tshaj plaws tshuaj ntawm 20 mg.

Erosive reflux esophagitis kho rau plaub lub lis piam nrog ib tug txhua txhua hnub koob tshuaj ntawm 40 mg. Thaum lub sij hawm ntev kev tiv thaiv ntawm kev rov muaj dua raws li nyob rau hauv lub txais tos txhais tau tias ib tug neeg mob nyob rau hauv uas esophagitis tau kho, txhua hnub koob tshuaj yog teev nyob rau hauv lub chav 20 mg.

Nyob rau hauv cov kev kho mob ntawm reflux oesophagitis, aimed ntawm hais qhov pib kab mob cov tsos mob, noj 20 mg ntawm tshuaj "esomeprazole". Npaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj thiab hmoov yog siv los tua H. Pylori, thaum muaj kev sib txuas lus nrog duodenal rwj, nyob rau hauv ib tug ua ke txoj kev kho - "esomeprazole" (20 mg), "clarithromycin (500 mg)," amoxicillin "(1 g). Tag nrho cov tshuaj noj ob zaug ib hnub twg.

Mob plab ulcers tshwm sim los ntawm narcotics yuav muab, nws yog pom zoo kom kho 20 mg "esomeprazole" ib hnub twg. Cov kev kawm tshuaj ib txwm muab mus rau ib tug kws kho mob noj mus rau hauv tus account lub noj qab haus huv ntawm tus neeg mob, tus kab mob no, cov heev ntawm nws cov hoob kawm, thiab lwm yam tseem ceeb tshaj.

Sab los "esomeprazole" tshuaj

Cov neeg mob uas muaj kev noj cov tshuaj no rau ib tug ntev lub sij hawm, yog nws muaj ntsis mus rau tsim ntawm glandular hlwv nyob rau hauv lub plab dua li lwm cov neeg mob. Qhov feem ntau heev phiv ces ntawm lub cev thaum lub sij hawm kev kho mob txhais tau hais tias "esomeprazole" qhia ntawv nyob rau daim ntawv thov allocates ib tug mob taub hau thiab ib co tsis zoo twv loj los ntawm tus mob huam, xws li: cem quav, flatulence, raws plab, xeev siab, ntuav, muaj mob nyob rau hauv lub plab mog. Los ntawm rarer phiv xws li kom qhuav ntawm lub mucosa ntawm lub qhov ncauj, kiv taub hau, urticaria, khaus, dermatitis. Lwm yam tshuaj yeej ua tau, yog li kev kho mob yuav tsum tau nqa tawm nruj me ntsis nyob rau hauv lub saib xyuas ntawm ib tug tshwj xeeb.

Overdose yog nrog los ntawm kev tsis muaj zog, ua xwm txheej ntawm cov kev phiv, xws li nyob rau ib feem ntawm lub digestive ib ntsuj av. Nyob rau hauv xws li mob, kev kho mob yog ua los ntawm xa cov tsos mob ntawm overdose thiab txij nkawm txoj kev kho. Lim Ntshav Hauv Lub twb yuav luag tsis xav ua hauj lwm, muaj yog tsis muaj antidote.

ceev faj

Cev xeeb tub poj niam "esomeprazole" analogs muab nrog huab ceev faj. Kev kho mob thaum lub sij hawm cev xeeb tub yuav tsum tau saib xyuas los ntawm ib tug kws kho mob. cov tshuaj yog tshuaj rau cev xeeb tub cov poj niam xwb nyob rau hauv cov neeg mob qhov twg tej yam zoo ntawm lawv lub cev ho tshaj lub peev xwm raug mob mus rau hauv plab me nyuam. Txhim khu kev qha cov ntaub ntawv nyob rau hauv cov nyhuv ntawm cov tshuaj nyob rau hauv lub embryo yog tseem tsis tau, kom deb li deb li sai tau yuav tsum tsis txhob kho mob nrog cov tshuaj no. Kev siv lub tshuaj "esomeprazole" thaum pub niam mis yog txwv tsis pub.

Thaum ua txhaum ntawm lub siab tshaj lub teeb koob yog tej rau kev kho mob (yog hais tias cov kev ua txhaum no yeej loj heev).

Thaum tus neeg mob lub tsos mob cim teeb liab, xws li hematemesis, dysphagia, xeev siab, tseem ceeb yuav txo nyob rau hauv lub cev hnyav thaum lub sij hawm kev kho mob lub sij hawm "esomeprazole" nyob rau hauv thiaj li yuav tshem tawm los yog lub rwj vim noj cov tshuaj nyob rau hauv lub xub ntiag ntawm lub xav tias tus kab mob, malignancy yuav tsum muab deleted. Yuav kom qhia tau tias cov phem xwm ntawm hlav yog tsim nyog los ua kev cai ib txoj kev tshawb no.

Cov neeg mob uas muaj ib tug tsis muaj sucrase-isomaltase, raws roj ntsha fructose intolerance cim txwv tsis pub kom taw "esomeprazole" txhais.

Sis "esomeprazole" nrog rau lwm cov tshuaj

Nrog rau cov simultaneous siv ntawm cov tshuaj nrog "citalopram", "clomipramine", "imipramine" tau potentiation ntawm cov kab mob, kev txhim kho ntawm lub active tshuaj nyob rau hauv cov ntshav. Thaum siv nyob rau hauv ua ke nrog "esomeprazole" txo efficiency "ketoconazole" "Itraconazole" worsens lawv haum.

Thaum txuas lub "esomeprazole" nrog "ATV" lawm ib tug tseem ceeb txo nyob rau hauv kis ntawm cov tshuaj no. "Esomeprazole" kev khiav hauj lwm qhia ntawv yog tsis pom zoo kom siv ib txhij nrog cov "phenytoin", "clomipramine", "imipramine" thiab cov tshuaj xws li "citalopram", "Diazepam", "Nelfinavir" thiab "Atazanavir". Cov theem ntawm cov tshuaj yog tau sawv rau hauv cov ntshav, ces nws tej zaum yuav ntshaw kom txo tau lawv koob tshuaj. Concomitant siv ntawm «esomeprazole" thiab txhais tau tias "clarithromycin" ua rau ib tug ntau yam pauv loj hloov nyob rau hauv raug "esomeprazole" tshwm sim nce nws txuam nrog inhibition ntawm cov metabolism hauv cov yeeb tshuaj. Uas yuav tsum tau ua tib zoo xam tau tias yog instrukiyu mus rau yeeb tshuaj thiab tham ib tug tshwj xeeb.

Tus nqi ntawm cov tshuaj, xyuas txog cov tshuaj "esomeprazole"

Cov tshuaj mas mas yuav kis tau nyob rau hauv cov ntsiav tshuaj daim ntawv. Cov khw "esomeprazole" no muaj nyob hauv cov lag luam tawm npe "Nexium" thiab "Emanera". Thaum twg koj yuav cov tshuaj "esomeprazole" nqi nyob rau hauv lub koob ntawm cov active tshuaj nyob rau hauv nws muaj pes tsawg leeg. Tus nqi ntawm cov tshuaj nyob rau hauv ib tug ntau npaum ntawm 20 mg ( "Emanera") yog hais txog 500 rubles. rau 28 ntsiav tshuaj thiab yog txiav txim los ntawm lub chaw tsim tshuaj paus. Tshuaj nrog ib koob tshuaj ntawm 40 mg ntawm lub active ingredient ( "Nexium" 28 ntsiav tshuaj) yuav raug muas 3000 rubles.

"Esomeprazole" muaj kev xyuas feem ntau zoo. Lawv muab sau cov tshuaj cuab yeej inhibit acid secretion, ob qho tib si basal thiab tsa. Cov tshuaj tau qhia siab miv nyuas siv zug nyob rau hauv cov kev kho mob ntawm tej yam kev mob uas phim indications teev nyob rau hauv cov kev qhia ntawv. Thaum lub sij hawm txoj kev kho, qhov no txhais tau tias yog ib tug me ntsis ntau yam ntawm cov kev phiv. Tsis yog txhua tus yog yooj yim nrhiav tau ib tug yeeb tshuaj nyob rau hauv pharmacies, ib co neeg mob uas tau txais "esomeprazole", tus nqi nkawd siab.

Cov neeg uas coj lub tshuaj los ntawm ib tug kws kho mob tom qab ib tug leej ntsiab txhais ntawm lub mob thiab pom zoo koob, kos ib tug tseem ceeb kev txhim kho nyob rau hauv kev noj qab nyob. Raws li cov kev txheeb xyuas, "Nexium" yog ntau nrov ntawm cov neeg mob tshaj "Emanera". Thaum "Nexium" pais plab muab cov tsos ntawm cov kev kawm tshwm sim tom qab li ib lub hlis tom qab pib ntawm txoj kev kho. Kev txhim kho cov kev mob yuav tshwm sim tom qab 1.5 lub lim piam ntawm kev kho mob. Sab los yog tsis tshua muaj heev. Tshuaj "Nexium" zoo, nws yuav pab nrog rau cov tshem tawm ntawm lub tej yam kev mob xa mus rau hauv cov lus qhia. Hais tias qhov tshwm sim yog zoo, nws yog tsim nyog los ua kom tiav tag nrho cov hoob kawm thiab tag nrho ua raws li tus kws kho mob pom zoo.

Analogs "esomeprazole"

Cov nram qab no kev xaiv peev xwm yuav txawv los ntawm analogues ntawm cov tshuaj:

• "Omeprazole" - kuj hu ua "Losek", "Omez", "Ultop";
• "Rabeprazole" - ib tug npaj paub tias hauv lub npe "Ontaym", "Zulbeks", "Noflyuks" "Pariet", "Hayrabezol";
• "Pantoprazole" ( "Sanpraz", "Kontrolok", "Nolpaza");
• "Lansoprazole" ( "Lanza", "Lanzoptol").

Tag nrho cov tshuaj muaj zoo xws li cov teebmeem, tab sis lawv txawv los ntawm txhua lwm yam nyob rau hauv lawv cov nqi.

Piv "esomeprazole" thiab "Omeprazole". Txawv ntawm cov tshuaj yog cuab kev. "Esomeprazole" yog ib qho isomer "omeprazole". Tej kev npaj no, pib los ntawm cov kev kho mob cov ntaub ntawv cov ntaub ntawv, muaj ib tug txiav txim kom zoo dua, tab sis ib tug zoo xws li cov kev txiav txim ntawm medicaments. "Omeprazole" yog ib tug yeeb tshuaj lub hauv paus tus nqi rau cov loj xov tooj ntawm cov kev phiv. Yog hais tias peb xav txog lub zog ntawm cov "esomeprazole", cov tshuaj yog hais raws li ib tug paub version of "omeprazole", tus nqi ntawm uas tau attracted ntau cov neeg mob. Txawm li cas los, "esomeprazole" tsawg tsawg yuav ua rau pliaj tshua, ces nws cov purchase yog suav tias yog ntau muaj txiaj ntsim tshaj yuav "Omeprazole".

"Rabeprazole" thiab "esomeprazole" muaj ib tug zoo tshuaj nyob tus yeees, lawv kho cov tib kab mob. Tab sis kws txawj ntseeg tau hais tias ib co kab mob, xws li Gastroesophageal reflux kab mob, "Rabeprazole" eliminates zoo, nws tshem tawm ntawm cov tsos mob zoo dua, nws muaj txhawb rau ceev ceev rov qab los ntawm cov hlab pas tej hauj lwm. Qhov uas tsis muaj ib tug zoo ntxim nyob rau hauv cov kev kho mob ntawm "esomeprazole" tej zaum yuav txuam nrog cov neeg tus yam ntxwv ntawm tus kab mob.

Yog hais tias tsim nyog, xaiv lub analogue yuav tsum tau nrog ib tug kws kho mob. Kho ntau attentive mus rau lawv noj qab haus huv, thiab dhau soj ntsuam nyob rau hauv lub sij hawm, ces rov qab yuav tsum tau ceev thiab koj yuav tsis txhob muaj ntau yam mob.