Tsim, Science
Yuav ua li cas yog tshaj tawm hauv xov nyob rau hauv biology ua? Lub ntsiab theem ntawm translation
Yuav ua li cas yog tshaj tawm hauv xov nyob rau hauv biology ua? Tom qab transcription nws yog tus thib ob yog ib feem ntawm lub hauv paus dogma ntawm molecular biology, uas qhia txog kev siv cov kev tshuaj ntsuam genetic code rau qhov siv thiab ua chains ntawm amino acids.
Tshaj tawm hauv xov thiab RNA molecules
Peb yooj yim molecular chav kawm ntawv ntawm ribonucleic acid (RNA) yog muab kev koom tes nyob rau hauv cov kev qhia ntawm cov noob uas encoded nyob rau hauv dezokseribonukleinovoy acid (DNA) ntawm lub cell. Lawv yog:
- tub txib RNA (mRNA)
- Portable RNA (tRNA)
- ribosomal RNA (rRNA)
Thaum koj tshaj tawm hauv xov ib tug tshwj xeeb lub luag hauj lwm no yog ua si los ntawm cov thawj ob hom ntawm RNA.
translation hauv paus ntsiab lus
Nyob rau hauv biology ua tawm yog ib tug complex txheej txheem thaum lub sij hawm uas cov ntaub ntawv muaj nyob rau hauv ib tug qauv ntawm RNA (mRNA), ib tug protein yog tsim. Cov kab sab ntawm mRNA yog nyeem siv cov kev tshuaj ntsuam genetic code. Sheer translation tshwm sim nyob rau hauv ib tug qauv hu ua ribosome uas yog ib yam ntawm cov Hoobkas rau protein synthesis. Qhov no cell organelle muaj me me thiab cov loj loj subunit thiab yog ib tug complex molecule muaj ob peb ribosomal RNA molecules, thiab kuj yog ib tug xov tooj ntawm cov proteins.
Yuav ua li cas yog tshaj tawm hauv xov nyob rau hauv biology ua?
Tshaj tawm hauv xov yog tus thib ob kauj ruam tom qab transcription. Thaum lub sij hawm no muaj dab, cov kev tshuaj ntsuam genetic code yog hloov dua siab tshiab rau hauv lub amino acids uas yog koom ua ke los ntawm peptide bonds. chains ntawm amino acids yog hu ua polypeptides, thiab nyob rau hauv lub ribosomes, me quav organelles uas ua si ib qho tseem ceeb luag hauj lwm nyob rau hauv tus txheej txheem ntawm cov protein synthesis. Yuav muab txhais li: biology ua translation - ib tug cellular txheej txheem nyob rau hauv uas ib tug saw ntawm cov amino acids yog ua los ntawm seev suab. Protein synthesis tshwm sim nyob rau hauv lub cytoplasm, qhov twg ribosomes muaj nyob rau.
Yuav ua li cas yog tshaj tawm hauv xov nyob rau hauv ib thiab nyob rau hauv qhov tseeb tau koom ua ke polypeptide? Muaj peb kauj ruam tseem ceeb - pib, elongation thiab txiav. Cov ntsiab lus uas yog siv nyob rau hauv lub transcription thiab los mus piav qhia cov creation ntawm lub RNA saw theem.
Xoom theem yog suav tias yog activating, thaum lub yam amino acid yog covalently ua txhua yam rau ib tug haum RNA (tRNA) thiab yuav "them". Txawm hais tias nws tsis yog technically ib kauj ruam nyob rau hauv neeg txhais lus, cov kauj ruam no tseem yog tsim nyog, raws li tau zoo raws li tag nrho tom ntej sawv daws yuav. Yog li ntawd, xav txog cov theem ntawm translation hauv ib nyob rau hauv ntau yam:
- Pib. Rau ntawm no theem, cov mRNA yog txuas mus rau lub tRNA, uas yog txuas mus rau hais tias amino acid. Tag nrho ua ke, lawv koom nyob rau hauv lub ribosome.
- Elongation. Qhov no elongation los ntawm qhov sib ntxiv ntawm cov amino acids yog nrog los ntawm cov tsim ntawm peptide bonds. Nws thiaj li tsim polypeptide. muab cov txheej txheem ntxiv tshaj thiab tshaj dua li ntev raws li lub saw tsis ncav cuag nws cov kev txwv, uas yog hais txog ib puas amino acids.
- Txiav. Thaum lub kawg teeb liab yog tau txais biosynthesis, ib tug polypeptide yog cais los ntawm lub ribosome. Thaum tso tshiab protein, tag nrho cov ntau yam ntawm broadcasting so.
Sophisticated thiab yog txheej txheem
Yuav ua li cas yog tshaj tawm hauv xov nyob rau hauv biology ua? Qhov no yog ib tug heev thiab nyob rau tib lub sij hawm kuj ceeb tias zoo-ncaav thiab yog txoj kev uas yuav muaj ib tug ntau ntawm Cheebtsam. Tag nrho lub zog, cov tshuaj tiv thaiv thiab lwm yam manipulations txig hauj lwm ua ke. Conversion ntawm cov noob nyob rau hauv cov nqaijrog tshuam nyob rau hauv ob theem: transcription thiab txhais lus. Txawm tias muaj tseeb hais tias thaum lub sij hawm thawj tsis muaj protein synthesis tsis tshwm sim tsis muaj tus thib ob nws yog tsis tau.
Tshaj tawm hauv xov yog cov theem kawg nyob rau hauv qhov kev siv ntawm cov ntaub ntawv nyob rau kev tshuaj ntsuam genetic theem. Qhov no txoj kev muaj peev xwm tsuas muab qhov chaw nyob rau hauv nyob hlwb, thiab nws yog ntau npaum li cas yooj yim tshaj yav dhau los matrix synthesis replication thiab transcription. Tus neeg txhais lus yuav tag nrho cov hom ntawm RNA, nees nkaum hom amino acids, enzymes ntau yam thiab thiaj li nyob. Hom chaw ntawm tag nrho cov txheej xwm li ua cellular organelle, lub ribosome.
Cov tsab fact yog lub sib haum ntawm tag nrho cov interacting ntsiab ntawm protein biosynthesis: lub tseem ntawm ntau enzymes yog aimed ntawm lub kev sib nrig sib paub nyob rau hauv cov molecular theem. Txawm pheej nrhiav tau failures thiab tsis instantly tshem tawm los ntawm enzymes, uas, nyob rau hauv tus, rau lawv thiab tsis teb cov lus.
pab koom tes
Raws li cellular ribosome tsiv raws tus tub txib RNA, yog maj tso tawm nws pib kawm ntawv, tuaj koom los ntawm ib tug txawv ribosome. Thiab tus naj npawb ntawm xws organelles ua hauj lwm ib txhij nyob rau hauv tib molecule, tej zaum yuav mus txog ob peb kaum tawm. Yog li, tsuas yog ib puag matrix yog siv coj los ua ke ib tug ntau yam ntawm molecular duplekatov polypeptide. no pab koom tes tau raug hu ua polyribosomes (polysomes).
Nyob ntawm seb dab tsi zoo ntawm cov nqaijrog yuav tsum particular ntawm tes los yog kab mob raws li ib tug tag nrho, muaj ib tug multi-polypeptide biosynthesis noob thiab tej tshuaj los ntawm ib co ntxawg mechanisms, uas seamlessly thiab li qhia siv kuj khiav lag luam ntawm tej theem ntawm qhov kev tso tawm ntawm caj ces, xws li thaum lub sij hawm tshaj tawm hauv xov.
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