Kab mob ntawm lub taub hau. Ua rau, kev kuaj mob, kev kho mob

Tus kab mob Farah yog thawj zaug uas tau piav txog nyob rau hauv 30-xyoo ntawm lub xyoo pua nees nkaum. Qhov no yog ib yam kabmob uas muaj keebkwm (calcification ntawm cerebral vessels). Feem ntau, qhov sib txawv ntawm cov pathologies, uas qhov cuam tshuam cov cheeb tsam ntawm lub hlwb thiab nws cov hlab ntsha. Calcium ntsev yog tso rau hauv cov phab ntsa ntawm cov hlab ntsha, cov hlab ntsha. Fara syndrome tau pom muaj hnub nyoog li ntawm 40-50 xyoos, tab sis nws tshwm sim los ntawm nws cov kev paub thaum ntxov.

Ib pawg ntawm cov kab mob neurodegenerative

Qhov no pab pawg neeg ntawm cov kab mob yus muaj los ntawm hauv paus poob siab system. Ib tug xov tooj ntawm cov neurons yuav ploj mus, thiab qhov no ua rau cov kev puas siab puas ntsws. Neurodegenerative kab mob yuav muaj ntau yam ua rau txawv thiab txawv cov kev tshwm sim. Nws yog yam ntxwv hais tias tag nrho cov kab mob ntawm pawg no tsis tsim nyog. Tag nrho cov kev kho mob uas siv yog symptomatic. Hais tias yog, nws facilitates qhov tshwm sim ntawm tus kab mob, tab sis tsis ua rau kev puas tsuaj ntawm puas qhov chaw. Kev hloov ntawm cov hlab ntsha tuaj yeem yuav zoo tshaj, tab sis cov txujci muaj ob qho kev tawm tswv yim thiab kev coj ncaj ncees. Cov kab mob xws li Alzheimer's, Parkinson's, Farah's. Raws li ib txoj cai, tus kab mob ntawm cov kab mob nyob rau hauv thaum ntxov theem yog nyuaj. Feem ntau, thaum ua kev kuaj mob, cov kws kho mob tso siab rau cov neeg mob cov lus tsis txaus siab thiab cov kev tshwm sim ntawm cov kev soj ntsuam ntawm lawv tus cwj pwm. Tab sis cov cuab yeej tseem ceeb yog tomography (computer, magnetic resonance).

Symptomatic ntawm tus kab mob

Vim tias tus kab mob no yog ib qho tsis tshua muaj tshwm sim, nws yog qhov nyuaj rau cov kws kho mob tshwj xeeb los muab qhov tseeb ntawm daim tawv nqaij mob. Cov tsos mob tuaj yeem tshwm sim tau yog tias tus neeg mob muaj hnub nyoog 40 xyoo. Hauv cov neeg yaus, Farah tus kab mob cov tsos mob yuav ua rau qhov muag plooj plooj. Hauv cov neeg mob, kev ua haujlwm ntawm kev txav, cov kev kho mob parkinsonism yog cuam tshuam. Tsis tas li ntawd, xws li cov paib xws li lub cev, mob plab hnyuv, lub plawv dhia ceev nrooj (chorea), tsis muaj kev txwv ntawm tes, taw tau pov thawj rau txoj kev loj hlob ntawm tus kab mob. Txij li thaum tus kab mob cuam tshuam qhov chaw ntawm lub hlwb, qhov kev ua tau zoo, kev puas hlwb muaj peev xwm txo. Cov tib neeg nco kuj raug txom nyem. Feem ntau ua txhaum thiab hais lus. Lwm yam kev nyuab siab ntsws xws li hnov mob, kev mob hlwb. Qhia qhov txawv ntawm cov menyuam yaus ntawm tus kab mob, uas yog nws tus kheej thiab cov tub ntxhais hluas. Cov tsos mob tseem ceeb yog: dystonia, chorea, qaug dab peg. Daim ntawv no yog cov neeg laus thiab laus dua. Nyob rau hauv cov ntaub ntawv no, muaj yog parkinsonism, hais lus tsis meej, lwm yam teeb meem nyob rau hauv lub paj hlwb. Tej zaum tseem yuav tsis tso quav.

Qhov ua tau ntawm tus mob hu ua Farah

Yog vim li cas cov kev loj hlob ntawm tus kab mob no yog tsis tau tsim raws nraim. Txawm li cas los, nws yog lub npe hu hais tias ib tug tej yam loj loj nyob rau hauv nws cov emergence yog mob ntawm lub qog, parathyroid qog. Nyob rau hauv cov ntaub ntawv no, cov teeb meem tshwm sim nyob rau hauv lub metabolic kev ntawm calcium thiab phosphorus. Cov kab mob sib kis zoo li no yuav tshwm sim thiab ua txhaum ntawm acid-base tshuav ntawm lub cev. Alkalosis ua rau ib qho tseem ceeb ntawm cov kua qaub. Tab sis cov alkaline compounds yog tam sim no dhau. Muaj kuj yog ib lub tswv yim tias lub kheesxaws ntawm Farah ua rau nws tus kheej hauv kev mob caj ces. Hais tias yog, mutates lub noob, uas yog lub luag hauj lwm rau kev pauv ntawm lub caij xws li calcium. Txawm li cas los, qhov no version muaj ntau yam contradictions. Paub cais tus neeg mob, thaum cov tsos mob ntawm tus kab mob manifested tom qab irradiation ntawm lub taub hau, raug tshuaj lom toxins, ua, nyob rau hauv cov me nyuam nrog Down syndrome. Tsis tas li ntawd, calcification tau kuaj pom cov neeg uas tau rubella (tsis tshua muaj tshwm sim). Lwm qhov ua rau ntawm calcification ntawm basal ganglia yog lub hnub yug raug mob.

Kev tshawb nrhiav txoj kev kuaj mob

Ua ntej pib mob tomography, cov neeg mob tau tshawb cov duab X-ray ntawm lub hlwb. Ua tsaug rau cov tsos ntawm txoj kev tshawb nrhiav niaj hnub no, cov kws tshwj xeeb tau txais ntau cov duab xwm txheej los ntawm thaj chaw. Txawm li cas los xij, nws tsim nyog sau cia tias lub computer muaj qhov sib txawv, tsis yog muaj teeb meem loj ntawm magnetic resonance, muaj ntau yam hauv cov duab khej. Thaum tshawb fawb feem ntau ntawm cov duab, cov cheeb tsam uas raug cuam tshuam no tawm mus rau lub qhov muag daj. Lawv me me loj. Feem ntau, cov kab ganglia, thalamus, thiab cerebellum hloov. Theem ntawm calcification yog kwv yees li tib yam li cov neeg hluas, uas yog cov neeg laus. Tsis tas li no, tsis muaj qhov sib txawv ntawm cov pawg neeg uas muaj tus kab mob Farah yog asymptomatic, thiab cov neeg uas muaj tus kabmob no muaj cov lus qhia tshwm sim.

Histological kev xeem

Thaum ua raws li kev tshawb nrhiav txoj hauv kev hauv lub hlwb, cov duab hauv qab no yog pom: cov hlab ntsha muaj qhov muag pom (qee thaj chaw). Thaum koj kov riam, lawv ua suab zoo ib yam li ib qho kev nyuab siab. Rau cov cim histological, cov khoom siv yog sampled: cov chaw ntawm lub paj hlwb cortex, basal ganglia, thiab cerebellum. Nws yog nyob rau hauv cheeb tsam ntawm lub yav tas uas calcification tshwm sim feem ntau. Ntawm cov hnoos qaub calcium ntsev yog tam sim no. Tsis tas li ntawd, feem ntau lawv kuaj tau ntawm cov hlab ntsha (me, nruab nrab), cov hlab ntses. Tsawg zaus (raug mob), Far tus kab mob cuam tshuam cov leeg. Conglomerates cov calcium uas muaj qhov loj me me muaj nyob thoob qhov ntev ntawm cov hlab ntsha, nrog rau cov ntaub so ntswg uas nyob ib sab. Tsis tas li ntawd nyob rau hauv cov ntaub so ntswg, muaj cov pom ntawm arsenic, txhuas, cobalt, mucopolysaccharides yog raug rho tawm.

Nqe lus ntawm kev kuaj mob

Nyob ntawm seb Phara tus kab mob puas muaj cov tsos mob, qhov kev kuaj mob kuj yuav ua tau me ntsis nyuaj. Feem ntau, nws tau kuaj pom tus kheej, ua ib qho tomography kom paub meej tias muaj kab mob txawv kiag li. Ua ntej ntawm tag nrho cov, tus kws tshaj tawm excludes ua txhaum ntawm calcium metabolism, lwm malformations. Tom qab ntawd tom qab kawm tiav (tom qab kawm X-ray). Cov kws kho mob hais tias ib qho teeb meem hauv qhov teeb meem kev kuaj mob yog hypoparathyroidism. Tus kab mob no, uas tshwm sim nrog lub txiaj ntsim ntawm parathyroid hormone. Vim li ntawd, qib calcium hauv cov ntshav txo, thiab theem ntawm phosphorus nce. Yog tias cov ntaub ntawv tom qab soj ntsuam cov kab mob striospallo-toothed, ces yuav tsum muaj kev ntsuam xyuas ntxiv kom paub qhov txawv ntawm hypoparathyroidism los ntawm ib yam li Phara's kab mob. Ua ntej tshaj, nws yog ib qho tseem ceeb rau kev txiav txim siab txog theem ntawm parathyroid hormone thiab calcium. Tsis tas li ntawd, thaum kev kuaj mob ua rau lub cev tsis muaj zog ntawm qhov kev ua siab phem. Muaj qee qhov kev xav hauv cov ntshav, kab mob ntsws pob txha. Tus Cwj Pwm Cuam Tshuam kis tus kab mob no txawv xws li Burneville's sclerosis.

Kev Kho Mob

Tshem tawm ntawm accumulations ntawm poov hlau, uas tsim nyob rau hauv lub hlwb thiab nws cov hlab ntsha, yog tsis yooj yim sua. Raws li ib txoj cai, kev kho mob ntawm xws li ib tug kab mob yog symptomatic. Ua ntej ntawm tag nrho cov, nws yog tsom ntawm kev txhim kho cov kev pauv ntawm calcium thiab phosphorus nyob rau hauv lub cev. Yog hais tias cov tsos mob muaj cai Parkinson tus kab mob, tus kws khomob tshwjxeeb prescribes tshwj xeeb tshuaj (levodopa). Tsis tas li ntawd, Phara tus kab mob, qhov kev kho mob ntawm nws tshwm sim, yuav kom txais cov antioxidants, cov neeg sawv cev rau kev txhim kho cov metabolism. Kev kho mob ntawm calcium channel blockers yog ices. Nws yog tsim nyog xav tias qhov tseeb hais tias tus kab mob yog heev tsawg thiab tsis zoo kawm. Feem ntau, kev kho tsis muaj zog rau cov tsos mob ntawm tus kab mob ntawm tus kab mob, tab sis tsis cuam tshuam rau cov teeb meem ntawm calcification.

Qhov kev sib tw rau tus kab mob

Vim qhov mob no cuam tshuam cov metabolism hauv lub hlwb, nrog rau cov calcium uas ntsev muaj cov nyhuv rau ntawm nws cov ntaub so ntswg, qhov kev khwv yees ntawm Farah tus kheej yog qhov tsis xwm yeem. Tus kab mob no maj mam nce, nrog rau hnub nyoog, calcium deposits nce. Ntawm chav kawm, tag nrho cov no tsis tshwm sim nyob rau hauv ib xyoos. Raws li txoj cai, cov kab mob neurodegenerative kev vam meej rau ntau xyoo lawm. Qhov teeb meem tseem ceeb yog qhov tsis muaj lus qhia txog tus mob no, thiab tsis muaj kev kho mob. Yog li, txoj kev kho yog tsom rau kev txhim kho lub neej ntawm tus neeg mob. Lwm qhov tsis zoo - tus kab mob no tsis paub hais tias yog thaum ntxov.