Prodrug "Parnavel": cov lus qhia rau kev siv

Kev npaj "Parnavel" phau ntawv qhia no qhia txog raws li ib tug prodrug, uas yog ib tug ACE inhibitor thiab muaj ib tug cim antihypertensive nyhuv. Lub lag luam ntawm qhov cuab tam yog lub kev sib tw inhibition ntawm ACE kev ua si, tom qab ua rau ib tug txo nyob rau hauv lub concentration ntawm angiotensin II. Los ntawm kev noj cov tshuaj "Parnavel" (cov lus qhia rau kev siv nws qhia) txo preload, afterload (OPSS), thiab cov kuj nyob rau hauv lub ntsig txog cov hlab ntsha, thiab tsub kom kev nyuaj siab kam rau ua. Raws li hais tus pharmacokinetic thaj chaw ntawm cov neeg, ces qhia pib cim hypotensive nyhuv thaum lub sij hawm thawj rau caum feeb tom qab cov thawj coj, xeeb nws siab tshaj plaws tom qab plaub los yog yim teev thiab persisting thoob plaws hauv lub hnub.

Qhov tshuaj "Parnavel", tus nqi ntawm uas nws txawv ntawm ob puas tsib caug rau peb puas rubles, nyob rau hauv daim ntawv ntawm cov pa round tshuaj. Muaj pes tsawg leeg ntawm ib ntsiav tshuaj raws li lub ntsiab active caij yog muaj nyob rau hauv lub Scope ntawm perindopril erbumine plaub milligrams.

Siv cov tshuaj "Parnavel" phau ntawv qhia xav kom ib lub hom phiaj ntawm cov kev kho mob ntawm tus kab mob ntaub ntawv ntawm lub plawv tsis ua hauj lwm los yog tawg. Cov thawj zaug koob tshuaj ntawm cov tshuaj, feem ntau yog ntawm ib tug thiab ob tug milligrams ib hnub twg rau ib lub sij hawm, thiab txij nkawm - ob mus rau plaub milligrams ib hnub twg.

Siv cov ntsiav tshuaj "Parnavel" kws txawj xav kom hais tias cov neeg nrog ib tug neeg intolerance ntawm perindopril erbumine li zoo raws li tag nrho cov neeg uas muaj ib tug predisposition mus rau lub kev loj hlob ntawm angioedema. Nyob rau hauv tas li ntawd, hauv daim ntawv ntawm ncaj qha contraindications rau kev siv muaj xws li cev xeeb tub thiab cov muaj hnub nyoog ntawm kaum yim. Lub lactation lub sij hawm zoo ib yam li yuav tsum caiv txhob noj cov tshuaj "Parnavel". Cov lus qhia rau kev siv Sau ntawv thiab cov undesirability ntawm nws siv nyob rau hauv cov ntaub ntawv ntawm kev mob loj tawg los yog tsim raum tsis ua hauj lwm. Cov neeg kev txom nyem los ntawm ib tug tshaj ntawm dej thiab sodium, ua ntej pib ib lub chav kawm ntawm txoj kev kho yuav tsum tau yuav tsum tau mus ua ib tug thiaj li hu ua kev kho ntawm cov dej electrolyte tsis txaus.

Nyob rau hauv tas li ntawd, koj yuav tsum ua tib zoo siv ib ntsiav tshuaj "Parnavel" ib txhij nrog tshuaj uas yuav ua rau ib tug tseem ceeb nce nyob rau hauv cov theem ntawm poov tshuaj.

Nyob rau hauv xaus, nws yuav tsum tau hais tias hais txog cov tau phiv tshuaj uas tej zaum yuav tshwm sim los ntawm kev noj cov tshuaj no. Piv txwv li, cov kws txawj nco ntsoov ib tug ncaj high kev pheej hmoo ntawm hnoos qhuav, mob taub hau, kiv taub hau, teeb ntawm saj thiab lub qhov ncauj qhuav. Nyob rau hauv tas li ntawd, tej zaum yuav muaj heev kev hloov ntawm mus ob peb vas, kev sib deev kawg, daim tawv nqaij ua pob liab vog, angioedema, qaug dab peg, erythema, daim tawv nqaij liab liab, khaus thiab ua xua. Nyob rau hauv tas li ntawd, tau txo nyob rau hauv hemoglobin index thiab ua rau kom cov theem ntawm uric acid thiab creatinine vim haus "Parnavel".