ACE inhibitors - zoo tshuaj uas niaj hnub Cardiology

Contact lenses los yog ACE angiotensin converting tau hu ua hwj chim vasodilators siv nyob rau hauv Cardiology rau cov kev kho mob ntawm kub siab. Qhov kev txiav txim ntawm no pab pawg neeg ntawm cov tshuaj yog heev thaiv cov hlab adrenal hormone angiotensin II - pressor ntsiab zoo tshaj rau cov ntshav siab nqi. ACE inhibitors tiv thaiv lub neej puas bradykinin, uas kuj muaj feem xyuam rau cov mob ntawm cov hlab ntsha, thiab chaw pib rau lub qhov siab ntawm cov ntshav siab. Cov tshuaj pab rau kom cov ntshav ntawm vasodilator prostaglandins txo cov tsos mob ntawm tus kab mob plawv tsis ua hauj, yog feem ntau pom nyob rau hauv cov neeg mob uas tseem ceeb tawg. Nyob rau tib lub sij hawm, ACE inhibitors, tsis zoo li lwm yam tshuaj uas txo cov ntshav siab muaj tsis ntxim rau piam thaj thiab lipid metabolism, txo urinary protein ob lub raum.

ACE inhibitors yog siv rau ntau tshaj 40 xyoo. Tus thawj ntawm pab pawg neeg no ntawm cov tshuaj nyob rau hauv 1975 tau tsim captopril, siv niaj hnub no. Ib tug ob peb xyoos tom qab ntawd nws twb tau enalapril thiab lisinopril. Lawv hloov los ntawm ntau niaj hnub ACE inhibitors ib tug tshiab tiam.

Nyob rau hauv niaj hnub Cardiology ACE inhibitors yog siv raws li lub ntsiab tshuaj rau kev kho mob ntawm hypertensive tus kab mob, ischemic lub plawv kab mob, mob hauv lub plawv tsis ua hauj lwm.

ACE inhibitors kev faib

Muaj ntau ntau classifications ntawm ACE inhibitors, uas yog raws li nyob rau hauv txoj kev tshem tawm ntawm cov tshuaj los ntawm lub cev, nyob ntawm seb cov tshuaj pab pawg neeg nyob rau hauv lub molecule interacting nrog ACE center ntawm kev ua si kauj ruam. Feem ntau kev faib ntawm lub pharmacological kev txiav txim.

Raws li cov pharmacological kev txiav txim ntawm angiotensin converting inhibitors tag nrho cov yam tseem ceeb yog muab faib ua peb pab.

Cov thawj pab pawg neeg yog captopril los yog hood, uas ncaj qha cheeb, i.e. cheeb qhov uas cov angiotensin converting kuv ua si ntawm cov hormone nyob rau hauv ib tug tom ntej theem - angiotensin II. Kom muaj captopril los yog kapoten ntshav siab coj peb mus rau plaub zaug ib hnub twg.

Rau qhov thib ob pab pawg neeg yuav enalapril, ramipril, trandalopril, tsilazipril, fosinopril, quinapril thiab lwm yam tshuaj uas hloov dua siab tshiab rau hauv lub cev mus rau hauv lub tebchaw uas muaj ib tug vasodilatory nyhuv. Cov tshuaj yog txaus noj ib zaug xwb ib hnub twg.

Thaum kawg, peb pab pawg neeg muaj lisinopril Zestril, prinivil, prestarium los yog perindopril. ACE inhibitors yog peb pab pawg neeg yog pom zoo kom noj ib zaug los yog ob zaug thaum lub sij hawm ib hnub.

Tshwm sim los ntawm ACE inhibitors

Thaum koj tau txais no pab pawg neeg ntawm cov tshuaj yuav tsum tau paub txog cov tau txoj kev loj hlob ntawm phiv los. Nyob rau hauv tej rooj plaub, noj ACE inhibitors yuav tshwm sim hnoos qhuav, muaj poov tshuaj ntau nyob rau hauv cov ntshav, kiv taub hau, tsis haum daim tawv nqaij sawv pob, angioedema. Cov teeb meem yog kiag li tshem tawm tom qab tshuaj ntsoos ntsoos. Qhuav hnoos tshwm nyob rau hauv lub thib peb-fifth hnub ntawm kev kho mob. Nws zoo li yog vim tsub zuj zuj nyob rau hauv lub ntsws ntawm bradykinin. Hnoos disappears kiag li tom qab discontinuation ntawm inhibitors. Ib txhia neeg tej zaum yuav txo tau qab los noj mov thiab ntxhov saj xaav.

Ib yam ntawm cov loj contraindications rau kev siv ntawm ACE inhibitors yog ob sab sib dho raum leeg constriction. Nyob rau hauv cov ntaub ntawv no, cov ntshav siab yog muaj zog los ntawm raising lub theem ntawm renin nyob rau hauv cov ntshav uas cov tshuaj muaj tsis ntxim.

Tshwj xeeb kev kho mob yuav tsum tau muab ACE inhibitors nyob rau hauv mob siab thiab mob raum kab mob rau txoj kev loj hlob ntawm cov tsos mob ntawm hepatic thiab raum insufficiency.