Ntshav monocytes nce: raws li evidenced los ntawm tsom xam ntawm lub

Tag nrho cov ntawm peb los ntawm lub sij hawm rau lub sij hawm ntsib nrog nraim kev kho mob cov lus. Txij li thaum CBC dhau txhua yam, muaj yog ib txwm rau lo lus nug tshwm sim, dab tsi yog qhov monocytes, yuav ua li cas muaj ntau yam ntawm lawv yuav tsum tau nyob rau hauv cov ntshav, thiab raws li evidenced los ntawm tus nqi tau thaum cov ntshav monocytes yog nce?

Monocytes - yog loj nyob rau hauv loj ntawm cov ntshav liab, teej tug mus rau cov chav kawm ntawv ntawm cov ntshav dawb. Raws li cov qauv - oval hlwb nrog ib tug loj nucleus thiab cov tsis muaj grain nyob rau hauv lub cytoplasm (agranulocytes) teb rau inflammatory dab nyob rau hauv lub cev nce nyob rau hauv lawv cov ntshav. Ib txoj kev mob nyob qhov twg cov ntshav monocytes yog txhawb, hu ua monocytosis.

Cov hlwb yog tsim nyob rau hauv lub hlwb pob txha ntawm monoblastov, thaum lawv raug muab faib los ntawm meiosis, thiab ib tug ob peb hnub tom qab ntawd migrate los ntawm cov ntshav mus rau hauv cov ntaub so ntswg, thiab muaj nyob rau ntawm lub cellular theem muab kev koom tes nyob rau hauv phagocytosis. Nyob rau hauv feem ntau tus neeg mob, tus txheej txheem no yog cai nyob rau hauv cov lus teb rau allergic ntawm tus kab mob thaum lub monocytes ua macrophages twb yog kev cob cog rua rau ntxiv kev tiv thaiv thiab thaiv cov hlab txawv teb chaws proteins uas kom tsim antigen-antibody ua ke. Nyob rau hauv tus txheej txheem ntawm phagocytosis ntawm monocytes yeej tsis lawm, raws li feem ntau tshwm sim nrog eosinophils thiab qe, tab sis tsim ib tug ncej defining site ntawm o. Ib tug yam ntxwv feature yog zoo li tus cwj pwm ntawm cov hlwb nyob rau hauv acidic ib puag ncig.

Monocyte muaj ib tug loj tus naj npawb ntawm lysosomes, uas zom cell fagotsitiruemye khoom scraping lesion site thiab npaj nws rau lwm. Yog mas monocytes nyob rau hauv cov ntshav, yog nplua mias rau tam sim no nyob rau hauv tus po, cov qog ntshav hauv thiab hloov hlwb pob txha, li ntawd, qhov kev raug mob ntawm ib qho ntawm lawv yuav txo monocytes. Monocytosis cov lus hais nyob rau hauv phem hlav, kis kab mob (syphilis, tuberculosis), cov kab mob (lupus erythematosus, cov kab mob ntawm cov ntshav), collagenosis, granulomatosis.

Tus txheem ntawm cov mononuclear leukocytes nyob rau hauv lub qub peripheral ntshav - tsis ntau tshaj 0.03 - 1.00 × 109 / L, thiab lawv tag nrho cov nyiaj yuav tsum tsis txhob ntau tshaj li 8-10 hom% ntawm tag nrho cov leukocytes. Yog hais tias monocytes saum toj no qhov txhia qhov nws yog lub sij hawm mus dhau ntxiv kev ntsuam xyuas kom paub tias cov qhov chaw ntawm kab mob thiab cov uas tsim nyog kho mob kev kho mob. Monocytes muaj cytotoxic nyhuv (nyhuv dejnum rau mob hlwb li zoo li nyob rau hauv cov kab mob xws li kis tau malaria), tsim lub tebchaw (IFN), yog muab kev koom tes nyob rau hauv lub Vocabulary ntawm txawv teb chaws cov neeg ua hauj.

Txawm hais tias cov ntshav monocytes yog nce, nws yog tsis yooj yim sua kom raug piav qhia txog lub predictive daim duab ntawm lub inflammatory txheej txheem, raws li heev dua lwm yam rau lawv ntau indicators. Rau lub hom phiaj no peb kwv yees tag nrho cov leukocyte mis ntawm cov ntshav: yog hais tias ib tug ntau ntawm monocytes, nrog ib qho kev nce rau hauv lub xov tooj ntawm lymphocytes thiab, thiab tib lub kev faib ua feem ntawm eosinophils, tab sis lub txo tus naj npawb ntawm T-lymphocytes cov ntsiab lus, nws yuav tau kev raws li ib yog vim li cas rau ib tug cov paaj sij hawm ntawm ib tug pathological mob. Nyob rau hauv sib piv rau lub xeev qhov twg cov ntshav monocytes nce raws li tus xov tooj ntawm Neutrophil leukocyte ua haujlwm mus rau sab laug, thiab ib txhij ib tug txo nyob rau hauv tus naj npawb ntawm eosinophils thiab T-lymphocytes.

Yog hais tias ib tug ntse poob nyob rau hauv lub xov tooj ntawm monocytes yog pom nyob rau hauv cov ntshav, ces nws los txog rau xws li ib tug lub xeev raws li monocytopenia (monotsitopeniya). Qhov no daim duab yog pom nyob rau hauv cov ntshav ntawm pob txha tsim muaj txhab, thaum tus txheej txheem gemapoeza ua txhaum nyob rau hauv generalized purulent kab mob, ntshav kab mob, hormonal tshuaj, kev nyuaj siab thiab poob siab yam teeb meem, yug menyuam thiab phais cov txheej txheem, raws li zoo raws li kev raug mob lub cev qhov twg monocytes yog raws li. Nyob rau hauv cov kev tshwm sim hauv lub xov tooj ntawm monocytes nyob rau hauv peripheral ntshav nws yog tsim nyog los ua kev cai ib tug thib ob mus kuaj ntshav. Nyob rau qhov no hauv paus, nws yuav raug muab tso rau cov coj txoj kev kho mob ntawm lub qhov pib kab mob. Txij li thaum monocytes teb mus rau lub xub ntiag ntawm kab mob nyob rau hauv lub cev, nws yuav tau teev tseeb hais tias lub ntsiab kom pom tseeb yuav tshuaj tua kab mob ntxiv symptomatic kev kho mob.