"Motonium": cov lus qhia rau kev siv, tiag tiag

Nyob rau hauv ntuav hais uas (reflex) tus txheem ntawm lub plab ntawm lub qhov ncauj. Feem ntau, xws li ib tug txheej txheem yog preceded by xeev siab thiab lo nqos cim, enhanced secretion ntawm cov kua muag, cov qaub ncaug thiab ceev ceev ua tsis taus pa.

Ua ke nrog cov remnants ntawm cov zaub mov, pais plab kua txiv, hnoos qeev, kua tsib thiab lwm yam impurities, ib tug txiv neej ejaculates thiab as-ham. Nws yuav ua rau lub cev qhuav dej thiab mob electrolyte tsis txaus. Yog li ntawd, thaum ib tug muaj zog thiab kev ntuav, nco ntsoov nqa ib tug xov tooj ntawm kev ntsuas uas yuav tseg tag nrho cov zaub mov thiab lwm yam hais nyob rau hauv tib neeg lub cev.

Ib qho ntawm feem nrov antiemetics yog "Motonium". Cov lus qhia rau kev siv, tiag tiag zog thiab contraindications ntawm cov tshuaj no muaj nyob hauv qab no.

Muaj pes tsawg leeg ntawm yeeb tshuaj, nws zoo lawm, ntim thiab cov hauj lwm

Nyob rau hauv dab tsi daim ntawv tso cov tshuaj "Motonium"? Phau Ntawv Qhia hais tias cov khoom no yog manufactured nyob rau hauv daim ntawv ntawm cov puag ncig thiab dawb zaj duab xis-coated ntsiav tshuaj. Lawv active ingredient ua raws li domperidone. Tsis tas li ntawd muaj nyob rau hauv lub medicament: lactose, microcrystalline cellulose, glycerol, pob kws starch, magnesium stearate thiab tsawg molecular yuag povidone. Nrog kev xav txog nto membrane, hais tias nws muaj hydroxypropylmethylcellulose thiab polyethylene glycol 6000.

Yuav tshuaj "Motonium" (los ntawm uas lawv tsa, peb yuav qhia rau hauv qab no) yuav ua tau nyob rau hauv cov hlwv los sis yas poom, ntim rau hauv cov duab los qhia thawv.

Qhov kev txiav txim ntawm cov tshuaj

tshuaj "Motonium" Yuav ua li cas yog nws ua hauj lwm? Cov lus qhia nyob rau hauv daim ntawv thov hais tias nws yog ib tug txhais tau tias yuav ua tau kom lub caij ntawm peristaltic lus nyob rau hauv lub duodenum thiab antrum ntawm lub plab. Tsis tas li ntawd, nws ho accelerates pais plab muab nchuav (thaum lub sij hawm deceleration ntawm tus txheej txheem), eliminates qhov kev xav ntawm kev xeev siab thiab ntuav, raws li zoo raws li esophageal sphincter laus nce (qis).

Yuav ua li cas lwm tus neeg yog zoo kawg li tshuaj "Motonium"? Xyuas qhia hais tias nws yeej txhawb qhov kev tso tawm ntawm prolactin los ntawm lub pituitary caj pas. Nws anti-emetic cov nyhuv yog tshwm sim los ntawm peripheral los yog gastrokinetic cawv thiab kev thaiv kev ntawm dopamine receptors nyob rau hauv lub chemoreceptor txhais tsam.

Peb kuj yuav tsum nco ntsoov tias domperidone muaj tsis ntxim rau cov pa ntawm pais plab kua txiv.

kev tig tau nta

Yuav ua li cas yog cov yam ntxwv ntawm cov kinetics ntawm cov tshuaj raws li "Motonium"? Cov lus qhia rau kev siv ntawm neeg pab leg ntaubntawv hais tias tom qab noj cov tshuaj, nws absorbed es sai sai.

Qhov no tshuaj muaj tsawg bioavailability (kwv yees li 15%). Nws ncov ntshav ntau cai tom qab 60 feeb.

Txo pais plab acidity kua txiv thiaj li tus txheej txheem ntawm haum ntawm domperidone. Nws tsis tau txeem cov ntshav-hlwb barrier, thiab yog li ntawd nws siv yog heev tsis tshua nrog kev phiv.

Lub medicament "Motonium", cov lus qhia rau kev siv uas yog qhia hauv qab no, yog zoo faib nyob rau hauv cov ntaub so ntswg. Txawm li cas los, nws concentration nyob rau hauv lub hlwb yog negligible. Ruaj rau ntshav cov nqaijrog npaj yog 91-92%.

Feem metabolized nyob rau hauv lub siab yog raug mus rau yeeb tshuaj thiab cov plab hnyuv phab ntsa. Nws ib nrab-lub neej sij hawm ntawm 9 teev, thiab nyob rau hauv lub raum tsis ua hauj lwm (expressed) nyob rau hauv cov nram qab no lub sij hawm yog lengthened.

Tso tawm cov tshuaj mob raum thiab los ntawm cov hnyuv.

Indications tau txais lam ntsiav tshuaj

Nyob rau hauv tej rooj plaub, tus neeg mob kev npaj "Motonium" yuav raug muab tso? Xyuas ntawm cov kws kho mob sib ceg hais tias qhov no tshuaj yog siv nyob rau hauv lub complex ntawm dyspeptic cov tsos mob txuam nrog pais plab los yog esophageal reflux, pais plab tshwm tso tawm los yog esophagitis. Yog li, cov kev kawm neeg sawv cev no yog siv nyob rau hauv flatulence, nov ntawm nqaij tawv ntawm fullness nyob rau hauv epigastrium, nov ntawm nqaij tawv ntawm tsam plab, belching, mob nyob rau hauv lub plab, thiab kub siab tsis muaj casting (los yog, conversely, nrog reflux) ntawm lub plab txheem rov qab mus rau hauv lub qhov ncauj.

Los ntawm tej yam uas lwm tus neeg yuav pab tshuaj "Motonium"? Cov lus qhia rau kev siv qhia hais tias qhov no npaj yuav rhuav tshem cov kev xav ntawm xeev siab, ntuav, tiv thaiv cov kev loj hlob ntawm ib tug organic, mob, thiab tej xwm, raws li zoo raws li tshwm sim los ntawm radiotherapy, noj cov zaub mov tsis meej, tshuaj kho mob thiab kev txais tos ntawm dopamine agonists (e.g., "Bromocriptine" los yog "Levodopa").

Contraindications tau txais cov nyiaj

Qhov no tshuaj nrog ceev faj yog pom zoo kom noj cov neeg uas muaj hepatic los yog lub raum insufficiency. Nyob rau hauv tas li ntawd, nws tsis yog tshuaj rau lub plab los yog plab hnyuv los ntshav, npau taws me ntsis, plob tsis so tswj perforation, los yog pais plab, neeg kho tshuab cov hnyuv rhuav txhua, raws li zoo raws li lub xub ntiag ntawm prolactinoma thiab nyob rau hauv lub hnub nyoog ntawm tsib lub xyoos.

Tshuaj "Motonium": cov lus qhia rau kev siv

Muab cov nyiaj yuav tsum yuav hauv rau 20-35 feeb ua ntej noj mov. Cov tshuaj ntawm cov tshuaj nyob rau hauv tus neeg mob tus mob.

Nyob rau hauv ntev dyspepsia cov me nyuam tsib xyoos medicament muab 2.5 mg / 10 kg lub cev hnyav ib hnub peb zaug. Nyob rau hauv muaj xwm ceev cov tshuaj yog coj thiab ua ntej yuav mus pw. Raws li rau cov neeg laus, lawv yuav xaiv 10 mg ntawm cov tshuaj (ie 1 ntsiav tshuaj) peb zaug ib hnub twg thiab, yog tias tsim nyog - cia li ua ntej yuav mus pw.

Yog hais tias yuav tsum tau, lub teev ntau npaum yuav muab ntau zog ob zaug.

Nyob rau hauv mob thiab subacute lub xeev (xeev siab thiab ntuav) rau cov neeg laus cov neeg mob muab 20 mg ntawm medicament (i.e. 2 ntsiav tshuaj) plaub zaug ib hnub twg, thiab ua ntej yuav mus pw. Cov me nyuam los ntawm tsib lub xyoos no lub cuab tam yog pom zoo kom noj 5 mg / 10 kg lub cev hnyav ib hnub peb zaug thiab thaum mus pw.

phiv

Xam tias yog antiemetic tsis tshua ua phiv tshua. Muaj mob ntawm nraum plab hnyuv tu-sauv, thiab extrapyramidal mob nyob rau hauv cov me nyuam thiab cov neeg uas muaj zog permeability ntawm lub BBB.

Tsis tas li ntawd, nyob rau hauv cov neeg mob uas tau txais cov tshuaj no tej zaum yuav tsim kev tsis haum tshuaj xws li urticaria thiab daim tawv nqaij ua pob ua xyua. Tej zaum active tshuaj ua hyperprolactinemia (gynecomastia thiab galactorrhea).

Overdose ntawm yeeb tshuaj

Yuav ua li cas cov tsos mob tshwm sim thaum noj siab koob tshuaj ntawm cov nyiaj? Kws txawj hais tias cov tshuaj no yuav ua rau koj nkees nkees, tsis meej pem thiab extrapyramidal tshua, tshwj xeeb tshaj yog nyob rau hauv cov me nyuam.

Rau cov kev kho mob ntawm xws tej yam kev mob rau tus neeg txais hluav ncaig thiab antihistamines. Thaum antiparkinsonian thiab anticholinergics yuav pom zoo tshwm sim ntawm extrapyramidal tshua tus neeg mob.

Sis nrog rau lwm cov txhais tau tias

Anticholinergic tshuaj neutralize cov nyhuv ntawm domperidone.

Sodium bicarbonate, "cimetidine" thiab lwm yam protivosekretornye thiab antacids txo lub bioavailability ntawm cov tshuaj.

Tshuaj tua kab mob teej tug mus rau cov pab pawg neeg ntawm macrolides, noj azole tshuaj, "Nefazodone" thiab HIV protease inhibitors domperidone kom lub concentration hauv cov ntshav.

Cov kev siv nyob rau hauv cev xeeb tub thiab lactating cov poj niam

Tshuaj "Motonium" yuav muab nyob rau hauv thawj peb lub hlis uas cev xeeb tub, tiam sis tsuas yog nyob rau hauv tshwj xeeb indications.

Cov niam cov kua mis domperidone ntau plaub lub sij hawm tsawg dua nyob rau hauv ntshav. Kws txawj tsis paub hais tias cov nyhuv yog tsis zoo domperidone nyob rau hauv xws ntau nyob rau hauv lub me nyuam mos. Yog li ntawd, kev pub niam mis yuav tsum tau txiav thaum tau txais tshuaj.

tej tswv yim pom zoo

Cov neeg uas muaj mob loj heev raum insufficiency, tshuaj ib nrab-lub neej ntau zog los ntawm 9:00 mus rau 20. Txawm li cas los, lub concentration ntawm cov tshuaj nyob rau hauv cov ntshav tseem qis tshaj nyob rau hauv cov neeg noj qab.

Vim lub fact tias cov tshuaj no tas los ntawm ob lub raum nyob rau hauv me me, nws kho tsev ntau npaum nyob rau hauv cov neeg mob uas raum tsis ua haujlwm zoo yog tsis yuav tsum tau. Txawm li cas los Ua koob tshuaj nws multiplicity yuav tsum raug txo kom ob zaug ib hnub twg (nyob ntawm seb cov neeg kawm ntawv tsis ua hauj lwm).

Mob thawj coj ntawm cov tshuaj, cov neeg mob yuav tsum tau nyob rau hauv qhov kev saib xyuas.

Cia lub sij hawm thiab tej yam kev mob ntawm txim

Saib cov tshuaj yuav tsum tau khaws cia nyob rau hauv ib tug qhuav qhov chaw, kev tiv thaiv los ntawm lub teeb thiab ncav cuag ntawm cov me nyuam me. Cia kub yuav tsum tsis muaj ntau tshaj li 25 degrees.

Lub txee lub neej ntawm cov tshuaj yog 24 lub hlis. Tsis txhob noj cov ntsiav tshuaj tom qab lub sij hawm ntawm lub sij hawm daim kev cai tswjhwm ntawm lub hnab.

Tshuaj "Motonium": tus neeg mob xyuas

Hais txog kev saib xyuas txhais tau tias muaj ntau li ntau rov los xyuas. Feem ntau cov feem ntau, lawv zoo. Tau txais kev pab hais tias cov tshuaj no yog heev zoo nyob rau hauv txo ntuav thiab eliminates cov kev xav ntawm xeev siab. Ntxiv mus, active tshuaj yog feem ntau siv los txo dyspeptic cov tsos mob.

Nyob rau hauv tas li ntawd mus kawm siab, cov hauj lwm zoo ntawm cov tshuaj no muaj xws li nws tsis muaj teeb meem loj contraindications thiab txaus. Nws yuav tsum tau muab sau tseg tias cov tshuaj "Motonium" yuav luag yeej tsis ua phiv, xws li nyob rau hauv cov me nyuam laus tshaj 5 xyoo ntawm lub hnub nyoog.