Los ntawm dab tsi pab "furazolidone"? Muaj pes tsawg leeg, phau ntawv, analogues ntawm cov tshuaj

Koj puas paub hais tias yog ib tug yeeb tshuaj "furazolidone"? Los ntawm tej yam no tshuaj yog tshuaj thiab yuav ua li cas coj lawv? Nyob rau cov no thiab lwm cov lus nug peb yuav teb nyob rau hauv cov ntaub ntawv ntawm qhov tsab xov xwm.

Tso daim ntawv ntawm cov tshuaj, nws muaj pes tsawg leeg

Qhov tseeb ntawm yog dab tsi ua rau "furazolidone" peb yuav qhia rau hauv qab no.

Raws li cov lus qhia, hais tias txhais tau hais tias nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj. Lawv lub ntsiab tivthaiv yog furazolidone. Tsis tas li ntawd, cov tshuaj muaj ib tug adjuvant xws li lactose.

Nyob rau hauv ib lub pob yog muag tshuaj "furazolidone"? Cov lus qhia rau kev siv (analogs ntawm cov neeg uas muaj npe hauv qab no) ntawm cov ntsiav tshuaj muaj nyob rau hauv ib tug duab los qhia pob. Nrog kev xav txog cov kev npaj, nws yog fej nyob rau hauv Valium Valium los yog ntim.

mechanism ntawm qhov kev txiav txim

Los ntawm dab tsi pab "furazolidone"? Raws li cov lus qhia, nws yog ib qho antibacterial tshuaj. Nws pharmacological nyhuv nyob ntawm tus xaiv npaum li cas. Thaum koj siv ib tug me me npaum li cas ntawm furazolidone tshuaj exhibits ib bacteriostatic nyhuv. Yog hais tias ntau npaum ntawm cov tshuaj yuav ua tau kom, nws muaj ib tug muaj zog bactericidal nyhuv.

Hais txog kev npaj "furazolidone" (los ntawm uas cov tshuaj, peb kawm tau tom qab), peb tsis tau hais tias rau cov nyiaj ua cim los ntawm ib co immunostimulatory nyhuv.

Lub antimicrobial nyhuv ntawm cov tshuaj nyob rau hauv kev saib xyuas yog vim lub peev xwm ntawm lub nitro pab pawg neeg yog txo mus rau ib tug amino pab pawg neeg. Qhov no tshwm sim nyob rau hauv qhov kev txiav txim ntawm cov kab mob enzymes.

Cheebtsam uas tau raug tsim nyob rau hauv tus txheej txheem ntawm kev txo lub nitro pab pawg neeg, muaj ib tug tshuaj lom nyhuv. Nyob rau hauv tas li ntawd, lawv thaiv ib tug xov tooj ntawm lom thiab tshuaj dab nyob rau hauv lub hlwb ntawm cov kab mob, raws li tau zoo raws li muaj feem xyuam rau lub sam xeeb thiab cov qauv ntawm lawv lub week.

Thaum uas siv cov furazolidone cai blockade (irreversible) NADH, thiab inhibition ntawm cov tricarboxylic acid voj voog. Tej nyhuv yeej txhawb kev cuam tshuam ntawm cellular ua pa ntawm kab mob, lag luam ntawm lub cytoplasmic membrane, ua nyob rau hauv txoj kev tuag thiab tshwm sim teeb meem microorganisms.

nta nyiaj

Vim lub peev xwm ntawm lub molecule furazolidone daim ntawv ceg nrog nucleic acids, xam tau tias yog txhais tau tias muab lub synthesis ntawm cov nqaijrog nyob rau hauv cov kab mob hlwb vim uas inhibited qhov sib npaug thiab kev loj hlob ntawm cov teeb meem microorganisms.

Los ntawm dab tsi pab "furazolidone"? Qhov no txhais tau tias zoo manifests nws tus kheej nyob rau hauv txo tiv thaiv. Cov thaj chaw ntawm cov tshuaj txuam nrog nws muaj peev xwm ua rau kom cov kev ua si (phagocytosis) thiab Nkij los txuam rau titer leukocytes. Nyob rau hauv tas li ntawd, lub hauv paus khoom siv ntawm lub cuab tam thiaj li zus tau tej cov co toxins los ntawm cov kab mob, yog li kev txhim kho cov zuag qhia tag nrho kev soj ntsuam daim duab npaum li cas lawm dua microbiological kev ntsuam xyuas pom tias tsis muaj tshwm sim.

thaj chaw ntawm cov tshuaj

Yuav ua li cas cov khoom yog cov yam ntxwv ntawm cov tshuaj "furazolidone"? Nyob rau dab tsi ua rau qhov cuab tam? Tshwj xeeb tau muaj pov thawj hais tias furazolidone tau inhibit monoamine oxidase. Qhov no feature ntawm cov tshuaj ua rau txoj kev loj hlob ntawm me me ntxhov siab nyob rau hauv cov neeg mob.

Tsis tas li ntawd nws yuav tsum tau muab sau tseg tias hais tias cov tshuaj tsub kom lub cev rhiab heev rau ethanol. Qhov no yuav ua tau kom ntev li ntuav thiab xeev siab thaum lub ob leeg siv ntawm cov tshuaj thiab dej caw.

Yog li ntawd los ntawm dab tsi pab "furazolidone"? Qhov no tshuaj yog zoo heev nyob rau hauv cov kev kho mob ntawm cov kab mob ntawm cov kab xwm, uas yog tshwm sim los ntawm cov kab mob kab mob los raug rau tus furazolidone. Tsis tas li ntawd, hais tias txhais tau hais tias zoo manifests nws tus kheej tiv thaiv protozoa thiab fungi Candida. Txawm li cas los, nws yuav tsum tau muab sau tseg tias ua ntej lub sij hawm teem tseg ntawm cov tshuaj tsim nyog los nqa tawm rhiab heev kev ntsuam xyuas.

Liam cov kws kho mob pom tias cov tshuaj muaj zoo tsis ntxim rau co pathogens, raws li zoo raws li purulent kab mob.

Tshuaj "furazolidone": dab tsi pab?

Ntsiav tshuaj nrog lub npe yog feem ntau siv los kho cov neeg uas muaj kab mob nyob rau hauv lub urogenital cheeb tsam. Nyob rau hauv tas li ntawd, lawv yog zoo heev nyob rau hauv lub xub ntiag ntawm cov kab mob ntawm lub digestive ib ntsuj av tau thiab daim tawv nqaij.

Teb rau ib lo lus nug nyob rau hauv los ntawm dab tsi, khoom "furazolidone", koj yuav tau xyuam xim hloov li nram qab no tej yam kev mob: kub taub hau, bacillary dysentery, khoom noj khoom haus lom, paratyphoid ua npaws, raws plab kab keeb kwm, vaginitis, enterocolitis, urethritis, giardiasis, trichomonas kab mob, Trichomonas coleitis, cystitis, kis tau kab mob qhov txhab thiab kub nyhiab, pyelitis.

Txwv tau txais medicament

Puas muaj tej contraindications "furazolidone" ntsiav tshuaj (kev pab los ntawm cystitis yog ib tug txhais tau tias zoo heev)? Raws li cov lus qhia, xam tau tias yog cov tshuaj yuav siv tsis tau thaum:

• lactase tsis muaj peev xwm thiab tsis muaj kev piam thaj-6-fosfotdegidrogenazy;
• npau taws me ntsis (ib lub zuj zus) rau lub Cheebtsam ntawm lub medicament;
• mob raum tsis ua hauj lwm hom (xws li end-stage) ;
• nyob rau hauv lub hnub nyoog ntawm ib lub hlis;
• kev pub niam mis;
• impaired raum muaj nuj nqi;
• cev xeeb tub;
• daim siab thiab NA;
• tsav tsheb thiab kev khiav hauj lwm txaus ntshai machinery.

Cov lus qhia rau kev siv ntawm cov ntsiav tshuaj "furazolidone"

Pab raws plab tshuaj xam tau tias yog zoo heev. Qhov no yog vim lub fact tias nws muaj peev xwm mus inhibit qhov kev loj hlob thiab kev tu tub tu kiv ntawm cov kab mob ua rau txoj kev loj hlob ntawm dysbiosis.

Qhov no tshuaj yog coj hais lus. Ntsiav tshuaj yuav raug nqos raws li ib tug tag nrho, thiab tsis muaj kev sib tsoo kua, tiam sis tsuas yog nrog kom ntau.

Noj tshuaj yuav tsum tau nqa tawm tsuas yog tom qab ib tug noj mov. Lub caij ntawm kev kho mob rau lawv, raws li tau zoo raws li ntau npaum li cas los ntawm koj tus kws kho mob ib lub zuj zus rau txhua tus neeg mob (nyob ntawm seb qhov xwm ntawm tus kab mob thiab tus neeg cov yam ntxwv ntawm ib tug neeg).

Puas "furazolidone" pab nrog rumbling nyob rau hauv lub plab? Ntawm cov hoob kawm, nws yuav pab. Tus neeg laus cov neeg mob rau cov kev kho mob ntawm cov zaub mov lom, dysentery thiab paratyphoid taw 2-3 ntsiav tshuaj tshuaj plaub zaug ib hnub twg. Length ntawm cov hoob kawm yog nyob ntawm seb heev ntawm tus kab mob thiab yog kwv yees li 5-10 hnub.

Saib cov tshuaj yuav siv tau nyob rau hauv mus. Nyob rau hauv cov ntaub ntawv no, nws raug tsa los ntawm 0.1-0.15 g plaub zaug ib hnub twg rau 3-6 hnub, ces ua ib tug so ntawm 3-4 hnub. Ntxiv mus, cov tshuaj yog resumed rau tib kab.

Rau cov kev kho mob ntawm giardiasis active tshuaj muab (rau cov neeg laus) ntawm 0.1 g plaub zaug ib hnub twg.

Rau cov kev kho mob ntawm Trichomonas urethritis siv 2 ntsiav tshuaj ntawm cov tshuaj noj ntawm tib lub multiplicity. Duration ntawm lub chav kawm nyob rau hauv cov ntaub ntawv no yog 3 hnub.

Rau cov kev kho mob vaginitis Trichomonas neeg laus cov neeg mob kom noj 0.1 grams ntawm cov tshuaj peb zaug ib hnub twg. Rau qhov zoo tshaj plaws kho kev los ntawm cov kev npaj no tej zaum yuav ua ke nrog cov tshuaj uas muaj furazolidone, tiam sis tsuas yog nyob rau hauv lub qhov quav thiab paum suppositories. Lub duration ntawm lub general chav kawm ntawm kev kho nrog cov tshuaj no yog 1-2 lub lis piam. Lub caij ntawm qhov ncauj tshuaj yuav tsum tsis txhob ntau tshaj peb hnub.

Qhov siab tshaj plaws ntau npaum (tib) rau cov neeg laus tib neeg yog 0.2 g thiab lub hnub - 0.8 g

Cov me nyuam mos los kho cov zaub mov lom, paratyphoid thiab dysentery koob ntawm cov neeg sawv cev yog txiav txim nyob ntawm lub cev hnyav thiab muaj hnub nyoog. Qhov siab tshaj plaws ntev ntawm txoj kev kho nyob rau hauv cov ntaub ntawv no yog 10 hnub.

Rau cov kev kho mob ntawm giardiasis cov me nyuam feem ntau muab 10 mg / kg ntawm cov tshuaj ib hnub twg. Qhov saum toj no-hais ntshaw nyiaj ntawm medicament muab faib mus rau hauv 4 koob tshuaj.

Rau cov kev kho mob ntawm kis tus kab mob qhov txhab thiab kub yus medicament pom zoo kom siv ntawm ib ntub dej-qhuav gauze cov ntaub qhwv los yog irrigations. Ua li no, furazolidone yav tas los npaj cov tshuaj rau hauv lub concentration ntawm cov uas yuav tsum yog 1: 25000.

Kev nqis tes ua los ntawm-cim

Raws li cov lus qhia ntawm cov nyiaj muaj tsawg toxicity. Txawm tias nyob rau hauv tej rooj plaub, tiv thaiv lub keeb kwm ntawm nws nkag tej zaum yuav tsim kev phiv xws li:

• anorexia, daim tawv nqaij ua pob liab vog, xeev siab, urticaria;
• ntuav, khaus, mob nyob rau hauv lub epigastric cheeb tsam, angioedema.

Yuav kom txo tau cov mob ntawm cov phenomena npaj pom zoo haus kom ntau kua. Koj yuav tsum tau siv antihistamines thiab vitamins ntawm pab pawg neeg B.

Thaum xav hais phiv tshua txais tos tshuaj yuav tsum tau txiav, thiab ces tam sim ntawd tig mus rau lub mus kawm tus kws kho mob.

Heev siv cov medicament tus neeg mob tej zaum yuav tsim hemolytic anemia thiab methemoglobinemia (mas nyob rau hauv tus me nyuam mos cov me nyuam mos thiab cov me nyuam mos). Tsis tas li ntawd, rau qhov suav hais tias cov tshuaj yus muaj los ntawm sab tshua xws li ua tsis taus pa, hnoos, hyperthermia thiab neurotoxic los.

Ib tug overdose ntawm tshuaj

Nyob rau hauv cov ntaub ntawv ntawm overdose nws txhais tau tias cov neeg muaj cai tshuaj lom lub siab raug mob, xws li mob tshuaj lom kab mob siab. Nws yog tseem tau txoj kev loj hlob ntawm polyneuritis thiab haematological kev txiav txim ntawm lub active tshuaj.

tshuaj cov kev sib tshuam

Thaum pa roj carbon monoxide-xeem tshuaj "furazolidone" nrog neeg uas hloov cov pH ntawm cov zis, muaj ib tug kev hloov tus nqi ntawm feem ntawm nws active tshuaj.

Nrog rau cov simultaneous siv tetracycline thiab aminoglycosides txhim khu lub pharmacological los ntawm furazolidone, thiab thaum twg tag nrho nrog rau lub "ristomycin" thiab "chloramphenicol" inhibited tus txheej txheem ntawm hematopoiesis.

Thaum tau txais furazolidone nrog haus dej haus cawv tsim disulfiramopodobnye cov tshuaj tiv thaiv.

Saib yeeb tshuaj yog tsis muab nyob rau hauv ua ke nrog antidepressants, ephedrine, inhibitors ntawm monoamine oxidase, tyramine, amphetamine thiab phenylephrine. Qhov no yog vim muaj kev pheej hmoo ntawm hypertensive los.

Analogs thiab xyuas

Hloov suav hais tias yog tshuaj yuav ua tau los ntawm txhais tau tias xws li "Betadine", "Laktozhinal", "Hexicon", "Chlorhexidine", "Gipozol", "Trihomonatsid", "Dafnedzhin", "Makmiror", "Depantol", "Yodoksid", "Yodovidon ".

Testimonials ntawm no medicament feem ntau zoo. Lawv cam tias "furazolidone" manifests nws tus kheej raws li ib tug heev zoo antibacterial neeg sawv cev. Nws yog zoo tshem tawm cov tsos mob ntawm cystitis, raws li zoo raws li daws nrog rau lwm cov teeb meem nyob rau hauv lub urogenital kheej thiab khoom dysbiosis.

Nyob rau hauv tas li ntawd mus rau lub zoo lus hais txog cov tshuaj no thiab tawm tsis zoo lub tswv yim. Lawv hais tias "furazolidone" tshuaj ua phiv xws li ntuav, daim tawv nqaij ua pob liab vog, xeev siab, thiab pob.