"Lasix" nyob rau hauv ampoules: cov lus qhia rau kev siv, tshuaj

Yuav ua li cas yog diuretics? Nws tshuaj muaj sib txawv tshuaj lug, uas inhibit qhov kev reabsorption ntawm ntsev thiab dej nyob rau hauv lub raum tubules, raws li zoo raws li kom lawv feem nrog cov zis. Tsis tas li ntawd, xws tshuaj kom zis ntau lawm, txo cov dej ntsiab lus nyob rau hauv serous kab noj hniav thiab lwm yam ntaub so ntswg.

Cov feem nrov txoj kev uas yog ib tug diuretic tshuaj "Lasix" (ampoules). Cov tshuaj ntawm cov tshuaj, nws cov lus qhia thiab indications yuav sib tham txog hauv qab no.

Daim ntawv ntawm cov tshuaj, nws ntim, muaj pes tsawg leeg

Uas Cheebtsam muaj tshuaj "Lasix" (nyob rau hauv ampoules)? Cov lus qhia rau kev siv hais tias tej yam khoom uas txoj kev npaj no yog furosemide. Tsis tas li ntawd, nws muaj xws li sodium tshuaj dawb, dej rau txhaj tshuaj thiab sodium hydroxide.

Qhov no tshuaj yog marketed raws li ib tug tshuaj rau w / o los yog w / w ntawv. Nws yog pob tshab thiab twb tsis muaj xim.

Nws ua qhov no neeg sawv cev nyob rau hauv qhov tsaus ntuj nti iav ampoules txhaum point, uas yog tau ntim rau hauv lub cell qhia los ntawm yas.

mechanism ntawm qhov kev txiav txim

Yuav ua li cas puas cov tshuaj "Lasix" (nyob rau hauv ampoules)? Cov lus qhia rau kev siv (intramuscularly no neeg sawv cev yuav tsum tau muab xwb nyob rau hauv cov tsev kho mob thiab nyob rau hauv tshwj xeeb mob) neeg pab leg ntaubntawv hais tias nws yog ceev yeeb yam diuretic sulfonamide derivative.

Active medicament muaj peev xwm sawv ntawm thaiv cov hlab system thauj ntawm poov tshuaj ions, sodium thiab tshuaj nyob rau hauv lub loj department voj ntawm Henle. Uas yog vim li cas txiav txim salureticheskim hais tias cov tshuaj nyob li nws cov sij hawm tuaj txog nyob rau hauv lub raum tubules.

Diuretic zog qhia txhais tau tias kev cob cog rua rau tus txheej txheem kev tsim txom sodium tshuaj dawb reabsorption nyob rau hauv hais tias ya (voj ntawm Henle). Raws li rau ob los, lub suspects muaj xws li ib qho kev nce nyob rau hauv cov zis ntim thiab poov tshuaj secretion nyob rau hauv lub distal tubule. Tsis tas li ntawd nyob rau tib lub sij hawm nws yuav tsub kom lub feem ntawm calcium thiab magnesium ions.

Ua thawj coj ntawm cov tshuaj tsis txo nws cov diuretic kev ua si. Qhov no yog vim lub fact tias cov tshuaj nyob rau hauv lo lus nug yog tau cuam tshuam lub glomerular-tubular tswv yim.

Peb tsis tau hais tias "Lasix" tshuaj ua stimulation (koob tshuaj-dependent) ntawm lub renin-angiotensin-aldosterone system.

nta tshuaj

Yuav ua li cas nta yog cov yam ntxwv ntawm "Lasix" tshuaj (ampoules)? Cov lus qhia rau kev siv ntawm neeg pab leg ntaubntawv hais tias lub plawv tsis ua hauj lwm yog ib tug tshuaj thiaj li load thiab lub siab nyob rau hauv cov hlab ntsha (pulmonary) thiab lub txhaws ntawm sab laug ventricle. Tsis tas li ntawd, qhov no tshuaj muaj ib tug hypotensive nyhuv uas yog tshwm sim los ntawm thawj ntawm cov ntshav ntim (circulating), ua rau kom sodium feem thiab txo nyob rau hauv cov leeg tshua (smooth) nyob rau vascular vasoconstrictor los.

Koob-dependent natriuresis thiab diuresis cai thaum noj cov tshuaj ntawm ib koob tshuaj 10-100 mg. Tom qab tso dej cawv 20 mg diuretic nyhuv cai tom qab ¼ teev thiab yog txuas ntxiv rau 180 feeb.

Heev Txoj kev lis ntshav thawj coj ntawm cov kab mob ntau nraaj tshaj dua bolus. Nws yuav tsum tau muab sau tseg tias nyob rau hauv excess tshuaj noj tshuaj npaum cas tseem ceeb nce nyhuv nyob rau hauv cov neeg mob tsis yog cai.

pharmacokinetic zog

Yuav ua li cas tig tsis xam qhovkev nyob rau hauv cov tshuaj "Lasix" (nyob rau hauv ampoules)? Cov lus qhia rau kev siv ntawd hais tias qhov ntim ntawm muab faib rau cov active tshuaj yog kev npaj 0.1-0.2 litres ib 1 kg ntawm tus neeg mob hnyav.

Furosemide zoo uake rau cov nqaijrog thiab tas unchanged los ntawm lub tso pa tawm nyob rau hauv lub proximal tubule.

Terminal ib nrab-lub neej ntawm cov tshuaj tom qab tso dej Txoj kev lis ntshav ntawm kwv yees li ib thiab ib nrab teev. Lub ntsiab muaj ntawm cov tshuaj yog tas nyob rau hauv niam cov kua mis thiab penetrates rau hauv lub placental barrier.

Indications rau kev siv ntawm cov tshuaj

Uas kab mob muab tshuaj "Lasix"? Cov lus qhia rau kev siv (ampoules / m thiab / nyob rau hauv) hais tias cov tshuaj yog indications ntawm cov hauv qab no hais tias:

• edematous syndrome ntawm lub plawv tsis ua hauj lwm ib tug mob xwm;
• syndrome nrog edema raum mob tsis ua hauj lwm hom;
• edematous syndrome ntawm mob plawv tsis ua hauj lwm cim;
• mob raum tsis ua hauj lwm, xws li nyob rau hauv kub thiab cev xeeb tub (nyob rau hauv thiaj li yuav txhawb tau cov kua feem);
• syndrome edematous nrog rau ntau yam siab cov kab mob (raws li ib tug complementary kho mob ua ke nrog aldosterone antagonists);
• syndrome edematous nrog nephrotic syndrome (kev kho mob ntawm cov kab mob lwm);
• lub taub hau lub hlwb edema;
• Yuam diuresis kev pab txhawb nqa thaum lub sij hawm tshuaj lom (i.e., tebchaw uas tas los ntawm ob lub raum nyob rau hauv unchanged daim ntawv no);
• hypertensive ntsoog.

Inhibitions rau cov kev taw qhia ntawm cov tshuaj

Nyob rau hauv tej rooj plaub, koj muaj peev xwm tsis nkag mus rau hauv lub tshuaj "Lasix" (nyob rau hauv ampoules)? Cov lus qhia rau kev siv (rau cov me nyuam ntawm kev siv lub cuab tam yog khom cais) hais tias cov tshuaj tsis tau siv nyob rau hauv:

• mob loj heev hypokalemia;
• raum tsis ua hauj lwm (xws li nyob rau hauv anuria);
• mob loj heev hyponatremia;
• hepatic precoma thiab coma;
• hypovolemia (tsis tshua muaj ntshav siab los yog tsis muaj) los yog lub cev qhuav dej;
• cev xeeb tub;
• ntse qhia kev ua txhaum ntawm lub outflow ntawm cov zis los ntawm txhua qhov chaw los (xws li cov unilateral txhab ntawm lub mob txeeb zig);
• kev pub niam mis;
• Npau taws me ntsis mus rau lub ntsiab khoom xyaw;
• yog hais tias koj tsis haum rau sulfonamides.

Siv cov tshuaj nrog ceev faj

Nyob rau hauv ib co neeg uas muaj huab ceev faj yuav tsum raug siv tshuaj "Lasix" (tsiav tshuaj)? Cov lus qhia rau kev siv hais tias xws li thawj coj ntawm cov tshuaj yuav tsum tau nyob rau hauv:

• lub xeev uas ntev li txos ntawm cov ntshav siab yog txaus ntshai (e.g., stenotic txhab ntawm lub coronary los yog cerebral cov hlab ntsha);
• hypotension;
• gout;
• los yog manifest latent mob ntshav qab zib;
• mob myocardial infarction (nrog rau cov kev raug mob ntawm cardiogenic poob siab)
• hepatorenal syndrome;
• mauj lupus erythematosus;
• impaired urinary outflow (prostate caj pas hyperplasia, hydronephrosis, narrowing ntawm lub qhov zis);
• hypoproteinemia;
• tsis hnov lus;
• raws plab thiab pancreatitis;
• ventricular fibrillation;
• nyob rau hauv ntxov ntxov cov me nyuam mos.

Tshuaj "Lasix" nyob rau hauv ampoules: cov lus qhia rau kev siv

Ib tug tshuaj rau cov tshuaj nyob rau hauv raws li cov xaiv regimen yuav tsum muab tsuas yog ib tug tej tus kws khomob tshwjxeeb. Nyob rau hauv appointing cov tshuaj tus nqi qis tshaj ntau npaum yuav tsum tau siv, uas yog txaus mus cuag lub Desired nyhuv.

Lub medicament yog muab intramuscularly xwb nyob rau hauv exceptional mob. Feem ntau, nws yog poured intravenously (maj mam 4mg ib feeb).

Yuav ua li cas npaum li cas yuav tsum tau siv "Lasix" nyob rau hauv ampoules cov tshuaj? Ntau npaum ntawm no neeg sawv cev nyob rau hauv lub pov thawj.

• Edematous syndrome ntawm lub plawv tsis ua hauj lwm ib tug mob xwm.

Cov thawj zaug koob tshuaj rau tus mob no yuav tsum tau 20-80 mg ib hnub twg. Raws li ib tug txoj cai, nws yog xaiv raws li lub diuretic teb. Nrog rau qhov no mob txhua txhua hnub ntau npaum ntawm cov tshuaj yog muab faib ua peb lub sij hawm.

• Edematous syndrome nyob rau hauv lub plawv tsis ua hauj lwm mob.

Cov thawj zaug koob tshuaj rau tus mob no yog 20-40 mg. Yog hais tias yuav tsum tau, nws yuav tsum tau ho.

• Edematous syndrome uas mob raum tsis ua hauj lwm.

Tej cov neeg mob yuav tsum tau ceev faj koob xaiv. Nws tsub kom maj mam, yog li ntawd cov kua tsis tshwm sim maj.

• Mob raum tsis ua hauj lwm hom (los pab txhawb dej feem).

Ua ntej yuav pib txoj kev kho yuav tsum tau tshem tawm hypotension thiab hypovolemia, raws li zoo raws li kev ua txhaum cai ntawm cov acid-puag thiab ntsha raws li txoj cai. Initial tso dej ntau npaum nyob rau hauv xws kab mob no yog 40 mg.

• Puffiness ntawm lub nephrotic syndrome.

Nyob rau hauv lub xeev no, thawj zaug koob tshuaj reserves 20-40 mg ib hnub twg. Feem ntau, nws yog xaiv rau lub hauv paus ntawm diuretic teb.

• Syndrome o daim siab mob.

Nyob rau hauv cov ntaub ntawv no, cov tshuaj yog muab raws li ib yam ntawm cov adjunct rau kev kho mob ntawm aldosterone antagonists.

• lub hlwb edema, hypertensive ntsoog.

Raws li nyob rau hauv cov kab mob xws tshuaj yog yuav tsum tau muab "Lasix" (ampoules)? Cov lus qhia rau kev siv hais tias cov thawj zaug koob tshuaj hais tias medicament thaum tej yam kev mob yuav tsum tau 20-40 mg (ntawm tso dej bolus). Nyob ntawm seb cov nyhuv uas cov koob tshuaj yuav raug tom.

• Kev them nyiaj yug ntawm yuam diuresis nyob rau hauv tshuaj lom.

Qhov no medicament yog muab tom qab tso dej Txoj kev lis ntshav ntawm ntsha kev daws teeb meem. Cov thawj zaug koob tshuaj nyob rau hauv cov ntaub ntawv no yog 20-40 mg. Thaum lub sij hawm kev kho mob nws yog tsim nyog los tswj thiab restore poob kua.

txiav txim sab

Puas muaj cov kev tsis zoo ntawm cov tshuaj "Lasix" (nyob rau hauv ampoules)? Cov lus qhia rau kev siv raws li cov nram qab no tshwm sim tsis zoo:

• chloropenia, hyponatremia, metabolic alkalosis, hypomagnesemia, hypokalemia, hypercalcemia;
• lub cev qhuav dej, hypovolemia;
• tsis muaj ntshav siab, puas siab nyob rau hauv lub taub hau, kiv taub hau, pom tau qhov sib cuam tshuam, mob taub hau, tachycardia, nkees nkees, cev qhuav dej, tsis muaj zog, qhov ncauj qhuav;
• nce theem ntawm triglycerides thiab roj uas txhaws taus, thiab ntshav ntawm urea thiab creatinine;
• impaired zib kam rau ua, interstitial nephritis;
• xeev siab, paresthesias, ntuav, raws plab, intrahepatic cholestasis, mob pancreatitis, nephrocalcinosis nyob rau hauv preterm me nyuam;
• tsis hnov lus, tawm pob, tinnitus, pruritus, exfoliative dermatitis, ua pob ua xyua los yog bullous txhab ntawm daim tawv nqaij, erythema multiforme, kub taub hau, purpura, photosensitivity, vasculitis;
• thrombocytopenia, leukopenia, eosinophilia;
• agranulocytosis, deposition ntawm calcium nyob rau hauv lub ob lub raum, aplastic anemia;
• rhiab ntawm lub qhov koob.

Thaum mus ntsib ib tug kws kho mob?

Tam sim no koj paub, dab tsi zoo ntawm sab cov tshuaj tiv thaiv yuav ua rau cov tshuaj "Lasix" (ampoules). Cov lus qhia rau kev siv (nyob rau hauv cov me nyuam thiab cov laus, cov tshuaj txhawb lub tib teebmeem) argues tias kev hloov nyob rau hauv cov ntshav duab, raws li zoo raws li rau mob tawv nqaij tsis haum los yog anaphylactic tshua yuav phomsij lub neej ntawm cov neeg mob. Yog li ntawd, thaum tej yam tsis zoo ces yuav tau mus ntsib ib tug kws kho mob sai li sai tau.

precautionary ntsuas

Yuav ua li cas koj yuav tsum paub ua ntej yuav siv cov tshuaj "Lasix" (nyob rau hauv ampoules)? Cov lus qhia rau kev siv (rau miv yog ib tug txhais tau tias thiab tsis haum cov tsiaj tsis muab) muab hais tias ua ntej thaum pib ntawm txoj kev kho yog tsim nyog los tshem tawm cov nyob ntawm cim teeb nyob rau hauv lub outflow ntawm cov zis.

Thaum lub sij hawm kev kho mob nws yog advisable mus noj cov zaub mov uas yog nplua nuj nyob rau hauv poov tshuaj. Txwv tsis pub, koj yuav tsum coj poov tshuaj-sparing agents.

Ib txhia phiv peev xwm cuam tshuam ib tug neeg txoj kev muaj peev xwm mus mloog zoo, uas yog tsis tshua muaj txaus ntshai thaum ua hauj lwm nrog complex machinery thiab tsav tsheb.