Reticulocyte - dab tsi yog qhov no? Reticulocytes: norm

Reticulocyte - yog ib tug hluas daim ntawv ntshav liab thiab lawv cov thawj ntawm. Ib tug noj qab nyob zoo neeg cov ntshav muaj los ntawm 0.2 mus 1.2% ntawm cov hlwb. Qhov no yog cov ntsiab lus ntawm reticulocytes txheeb ze mus rau lub erythrocytes. Laus lub sij hawm ntawm nruab nrab ntawm 4 mus rau 5 hnub.

Reticulocyte - dab tsi yog qhov no?

Ib tug yam ntxwv feature ntawm cov tub ntxhais ntaub ntawv yog lub xub ntiag ntawm erythrocytes nyob rau hauv lub cytoplasm granular filamentous tshuaj uas nruab nrab yog aggregated mitochondria thiab ribosomes. Qhov no tshuaj yog kuaj tau los ntawm ib tug tshwj xeeb txoj kev uas tseg tau smears ntawm cov ntshav. Qhov no tsuas yog hu ua reticulocytes supravital, piv txwv li Nws yog ua los tsis mus los ntawm pre-fixation ntawm lub hlwb.

reticulocyte pab pawg neeg

Nws muaj tsib pawg ntawm reticulocytes. Lawv txawv nyob rau hauv lub reticular reticulum. Cov tuab mesh, lub reticulocyte yau.

Tus reticulocyte - yog ib tug cell muaj lub mesh nyob rau hauv daim ntawv ntawm ib tug tuab tangle. Tej hlwb yog reticulocyte 1 pab pawg neeg. Ntau mature reticulocytes tshwm sim raws li ib yam khoom uas nyob rau hauv daim ntawv ntawm kom meej meej pom kab laug sab leeg. Thiab 4-5 pab pawg nws zoo nkaus li nyob rau hauv daim ntawv ntawm ib tug neeg filaments thiab granules. Feem ntau cov neeg noj qab nyob zoo ntshav yeej 4 thiab 5 pawg reticulocytes, piv txwv li ntau mature. Lawv ua li 80% ntawm cov reticulocytes. Tab sis muaj tej yam pathologies, thaum lwm yog muaj zog, muaj ib qho kev nce ntawm reticulocytes 1-3 pab pawg, i.e., hluas ntaub ntawv. Qhov no yuav pom nyob rau hauv cov nram no pathologies:

• Nyob rau hauv cov ntaub ntawv ntawm ib tug muaj kev ntxhov thaum retikulotsitarnogo B12-deficient anemias.
• Hemolytic anemia thiab al.
• Erythroleukemia.

functions ntawm reticulocytes

Reticulocytes muaj nuj nqi zoo xws li cov erythrocytes, raws li thauj oxygen mus rau lub ntau yam ntaub so ntswg thiab kabmob, tab sis lub efficiency ntawm tus txheej txheem no yog me ntsis qis tshaj nyob rau hauv mature erythrocytes. Reticulocytes muaj peev xwm ntawm adsorbing molecules ntawm hlau muaj nyob rau hauv hemoglobin vim transferrin receptors.

Raws li cov ntshav yog noj rau reticulocytes?

Piv txwv uas koj tso ib tug mus kuaj ntshav. Reticulocytes - yog dab tsi? Puas muaj tus tsom xam lawv nrhiav tau nrog tej? Ntshav zauv rau qhov ntsuas no ua thaum lub sij hawm kev tsom xam. Yog hais tias tsim nyog, tus kws kho mob tau tsa ntsuam qhia nyob rau hauv cov kev taw qhia uas koj xav tau kom ntxiv reticulocyte suav.

Tshwj xeeb kev cob qhia, no tsom xam tsis tau, tab sis tseem txiav txim siab coj nws nyob rau hauv thaum sawv ntxov nyob rau ib npliag plab. Qhov no tsom xam yuav ua tau nyob rau txhua lub sij hawm, yog tias tsim nyog. Ntshav tawm ntawm tus ntiv tes, nws kev tshawb fawb yog nqa tawm nyob rau hauv lub tuam tsev ntawm hematology laboratory.

Reticulocyte count tsim ib tug supravital tsuas smear me me txoj kev, i.e. los ntawm suav lawv tus xov tooj nyob rau hauv ib tug tshuab kuaj kab mob. Nyob rau hauv modern laboratories, muaj kho vajtse reticulocyte suav txoj kev mus rau hnub tim.

Yuav ua li cas mus pub yus cov ntshav rau reticulocytes? Yuav ua li cas yog nws thiab nyob qhov twg xws li ib tsom xam yog khiav? Cov lus nug no yog teb. Tam sim no wb tham txog dab tsi tseem ceeb rau qhov ntsuas no.

Reticulocytes. Los nyob rau hauv lub ntsuam

Yuav ua li cas yog lub nqi ntawm cov ntshav liab nyob rau hauv peripheral ntshav? Pw ua ke sib txawv nyob rau hauv cov qauv muaj nqi tsuas yog tom qab 11-12 xyoos thaum xam xyuas qhov Performance index li reticulocytes nyob rau hauv cov ntshav. Cov cai nyob rau hauv cov me nyuam nyob rau hauv no muaj hnub nyoog yog tib yam. Tom qab cov ntxhais pib kev ua poj niam, coj khaub ntshav poob leads mus rau ib expansion ntau yam ntawm erythroid hlwb oscillations.

Nyeem reticulocyte cai nyob rau hauv lub peripheral ntshav yuav ua tau nyob rau hauv lub rooj hauv qab no.

Li cas rau cov kev nce rau hauv reticulocytes?

Tshwj xeeb yog ib qho tseem ceeb yog lub quantification ntawm reticulocytes nyob rau hauv anemias. Ib txoj kev mob nyob rau hauv uas muaj zog reticulocytes, hu ua reticulocytosis. Qhov nce nyob rau hauv cov hlwb, nrog los ntawm ib qho kev nce nyob rau hauv hemoglobin ntau ntau, cim tias seb thaum ib tug zoo regenerative muaj peev xwm ntawm cov pob txha. Nyob rau hauv kev, muaj zog reticulocytes yog cov nram qab no pathologies:

• Hemolytic anemia (cov kab mob uas koom nrog kev puas tsuaj ntawm erythrocytes - hemolysis) - reticulocytes yuav ua tau saum toj no 60%. Tshwj xeeb yog active tivthaiv nce nyob rau hauv hemolytic crises.
• Los ntawm lub cev hemotoxin uas hemolysis tshwm sim. Qhov no yuav ua tau ib tug tshuaj lom viper los yog cov tshuaj siv los kho eritremii. Co toxins nyob rau hauv malaria kuj ua hemolysis.
• Mob posthemorrhagic anemia (tom qab loj heev ntshav poob). Retikulotsitarny ntsoog feem ntau tshwm sim 3-4 hnub tom qab cov ntshav tsis tau. Tej zaum nws qhia thaum los ntshav, xws li mob plab kiav txhab los yog typhoid fever thiab lwm tus neeg.
• Polycythemia.
• Malaria.
• Cov rov qab lub sij hawm tom qab cov kws khomob los yog tawg txoj kev kho.
• hloov hlwb pob txha metastases.
• Xws li ib tug lub xeev tej zaum yuav tshwm sim nyob rau hauv mob oxygen tsis muaj peev xwm.
• Tom qab lub sij hawm teem ntawm ib lub chav kawm ntawm vitamin B12 nyob rau hauv cov kev kho mob ntawm B12-deficiency anemia.
• Thaum tau txais cov medicament "Erythropoietin" uas yog siv los kho anemia.
• Tom qab heev siv ntawm tej yam anti-inflammatories thiab antipyretics.
• Tom qab daim ntawv thov ntawm lub "L-dopa" Parkinsonism.
• Thaum haus luam yeeb.

Reticulocytosis paub qhov txawv yeej muaj tseeb thiab cuav.

Yeej muaj tseeb thiab cuav reticulocytosis

Nyob rau hauv qhov tseeb reticulocytosis nce ntawm cov tub ntxhais cov ntshav liab txuam nrog rau kev xov tooj ntawm lawv nyob rau hauv lub hlwb pob txha. Nws qhia tau hais tias tus txheej txheem ntawm erythropoiesis, piv txwv li, qhov tseeb tsim ntawm cov ntshav liab.

Thaum cuav reticulocytosis reticulocytes nce xwb nyob rau hauv lub peripheral cov ntshav thiab cov pob txha, lawv muaj pes tsawg poob los yog tseem zoo. Qhov no tej zaum yuav qhia leaching lawv mus rau hauv cov hlab ntsha ntawm lub hlwb pob txha. Ib tug zoo xws li cov txheej txheem no tshwm sim thaum lub sij hawm inflammatory dab los yog mob nyob rau hauv lub hlwb pob txha, xws li metastases.

Li cas rau cov yuav txo tau ntawm reticulocytes?

Number of reticulocytes decreases li cov inhibition ntawm erythropoiesis. Qhov no yuav tshwm sim nyob rau hauv xws pathologies li:

• Aplastic anemia (ib lub neej-hem mob ntawm tus neeg mob).
• B12-deficiency anemia.
• Hlau deficiency anemia.
• Folic acid deficiency anemia.
• Sediroblastnaya anemia.
• Thalassemia.
• Neoplastic dab lub hlwb pob txha.
• Thyroid mob lag luam (yuav txo tau cov nuj nqi), xws li myxedema.
• Loj raum tus kab mob, uas tej zaum yuav tsim nyog tau ntawm ib tug thawj ntawm erythropoiesis.
• Loj alcoholism, uas ua rau yus mob loj heev ntawm daim siab thiab ob lub raum.
• Mob mob.
• Thaum uremia - lub xeev ntawm lub raum tsis ua hauj lwm, uas yuav ua kom muaj ntshav ntawm nitrogenous tshuaj.
• Thaum txais tos ntawm tej yam tshuaj, xws li "Carbamazepine" los yog "chloramphenicol" thiab Propafenone sulfonamides.

Peb pom tawm li cas yuav muab ib tug xws li ntshav raws li ib tug reticulocyte. Cov tub liab hlwb, los ntawm uas ntxiv muaj ib tiav ntshav liab ntawm tes, uas cov khoom siv tag nrho cov ntaub so ntswg thiab kabmob ntawm lub cev nrog rau oxygen.