"Nimid" (ntsiav tshuaj): Cov Lus Qhia rau kev siv thiab cov tswv yim

Cov neeg kev txom nyem los ntawm cov kab mob ntawm cov pob txha, pob qij txha thiab cov nqaij raws li ib tug symptomatic kev kho mob cov kws kho mob feem ntau muab "Nimid" (ntsiav tshuaj). Cov lus qhia rau kev siv cov kev qhia tias cov tshuaj tsis tau tsuas yog tshem tawm qhov mob, tab sis kuj muaj anti-inflammatory kev txiav txim. Wb sim mus xyuas qhov kev kawm ntawm cov khoom nyob rau hauv ntau yam thiab nrhiav tau tawm nyob rau hauv uas tus neeg mob nws muaj peev xwm mus pab tau.

Drug daim ntawv thiab muaj pes tsawg leeg

Nrog kev xav txog cov ntaub ntawv ntawm qhov kev siv yeeb tshuaj, ces niaj hnub no nyob rau hauv pharmacies yuav tau ib ntsiav tshuaj, ib ncua kev kawm, granules thiab gel. Lub ntsiab active muaj nyob rau hauv lawv yog nimesulide. Ntsiav tshuaj formulation ntawm cov tshuaj tso tawm nyob rau hauv 10 daim hlwv. Ib tug ntsiav tshuaj muaj 100 mg ntawm nimesulide, thiab raws li koom haum pab Cheebtsam siv pharmacists microcrystalline cellulose, sodium stearate, croscarmellose sodium thiab Aerosil 200. ntawd muaj tej ntaub ntawv hais txog cov muaj pes tsawg leeg "Nimid" npaj (ntsiav tshuaj) cov lus qhia rau kev siv.

Lub hmoov ua ib koob tshuaj sachets. Qhov no daim ntawv ntawm cov tshuaj pab tau rau cov kev kho mob ntawm cov me nyuam. Tseeb, nyob rau hauv muaj pes tsawg leeg, tsuas yog nimesulide, povidone K-30, tabletozy 80 thiab Aerosil 200 muaj cam xws li sodium saccharin, citric acid, thiab flavorings. Scarce zoo siab rau haus ib qab siav nws niam nws txiv kho "cocktail".

Nyob rau hauv 1 ml ntawm kev ncua, thiab 1 g ntawm gel muaj 100 mg ntawm nimesulide. Raws li ib tug koom haum pab tivthaiv nyob rau hauv cov ob hom siv propylene glycol, sodium gidroskid, carbomer 940, disodium edelat, aromotizator, purified dej thiab methylparaben.

Lub pharmacological kev txiav txim ntawm cov tshuaj

Nimesulide, uas yog lub active ingredient ntawm lub medicament belongs rau cov pab pawg neeg ntawm nonsteroidal anti-sulfonanilides. Ib zaug nyob rau tib neeg lub cev, nws xaiv cheeb COX-2 thiab cheeb qhov uas cov synthesis ntawm prostaglandins nyob rau hauv inflammatory locus. Analgesic, antipyretic thiab anti-inflammatory nyhuv yog tiav tom qab ib tug ib "Nimid" Ntsiav tshuaj. Cov lus qhia rau kev siv muaj cov lus qhia ntxiv hais txog cov kev tshuaj tshuaj.

Nyob rau hauv tas li ntawd mus rau saum toj, cov tshuaj yog tau inhibit qhov kev tso tawm ntawm cov pa dawb radicals thiab inhibit qhov kev tso tawm ntawm myeloperoxidase, uas tsis muaj cov nyhuv rau chemotaxis thiab phagocytosis dab.

Raws li rau lub anti-inflammatory kev txiav txim ntawm cov tshuaj, nws yog tiav los ntawm nimesulide muaj peev xwm inhibit inflammatory kev sib kho thiab txo mob necrosis yam. Los ntawm inhibiting lub synthesis ntawm interleukin-6 thiab urokinase npaj "Nimid" (phau ntawv qhia qhia no fact) tiv thaiv degradation ntawm proteoglycans thiab collagen pob txha mos. Nyob rau hauv tas li ntawd, nimesulide tuav blocks rau nociceptive mob impulses system.

Yog hais tias peb xav txog lub mechanism ntawm analgesic txiav txim, nws yog txuam nrog inhibition ntawm histamine tso tawm txheej txheem ntawm heev heev mast hlwb thiab tus ntawm active compound ib glucocorticosteroid receptors.

Yog hais tias koj tus kws kho mob muaj kws kho "Nimid" (ntsiav tshuaj), mus rau cov lus qhia rau kev siv yuav tsum tau ua tib zoo xam tau tias yog ua ntej noj cov tshuaj. Tom qab tag nrho, qhov no daim ntawv muaj tswv yim pom zoo uas yuav tsum tau coj mus rau hauv tus account thaum lub sij hawm hauv chav kawm ntawm kev kho mob.

tshuaj

Tom qab tau txais cov pom zoo koob ntawm cov tshuaj no yog muaj kev koom absorbed los ntawm cov hnyuv ib ntsuj av. Thiab tom qab uas 1.5-2.5 teev qhia nyiaj pab ntau tshaj concentration ntawm active muaj nyob rau hauv cov ntshav ntshav. Ib tug yam ntxwv feature ntawm kev npaj yog lub siab muaj peev xwm mus nrog cov nqaijrog, raws li zoo raws li lub allergic ntawm cov ntshav hlwb barrier thiab gematoplatsentarny. Thaum END ntawm nimesulide yog txiav txim ntawm ib tug locus mob, thiab nyob rau hauv synovial cov kua.

tshuaj metabolism tshwm sim nyob rau hauv lub siab, thiab lwm yam, rau qhov cov nyob rau hauv unchanged daim ntawv active metabolites, yog tshem tawm ntawm ob lub raum (nyob rau hauv cov zis), nyob - lub faeces. Lub ib nrab-lub neej ntawm lub active tshuaj yog tiav los ntawm 3.5-5 lub sij hawm. Nws muaj ntau kev pharmacokinetic cov ntaub ntawv "Nimid" npaj cov lus qhia rau kev siv.

zaj lus tim khawv

Zoo medicament kub taub hau uas nrog cov kab mob ntawm Upper pa ib ntsuj av tau thiab Upper pa ib ntsuj av. Heev feem ntau muab ib tug yeeb tshuaj rau cov neeg kev txom nyem los ntawm rheumatoid mob caj dab, myalgia, osteoarthritis, bursitis, tendonitis, thiab lwm yam nqaij mob, cov pob txha thiab sib koom tes, nrog mob syndrome. Nyob rau hauv cov kev kho hniav thiab gynecological xyaum rau postoperative mob thiab postrevmaticheskih kuj siv "Nimid" medicament. Cov lus qhia rau kev siv nyob rau hauv xws li mob nws yog advisable mus yuav ib ntsiav tshuaj, hmoov los yog granules.

Nrog kev hwm mus rau yeeb tshuaj nyob rau hauv gel daim ntawv no, hais tias nws yog npaj rau cov tshuaj pleev siv nyob rau hauv lub kub lug cov ntaub so ntswg (mos) uas yog tshwm sim los ntawm ntau yam traumas. Zoo txhais tau tias tseem nyob rau hauv inflammatory dab thiab degenerative mob ntawm lub licas, osteoarthritis, ankylosing spondylitis , thiab lwm tus neeg. Nws muaj ib txhab daim ntawv teev cov indications rau kev siv ntawm cov nyiaj "Nimid" cov lus qhia rau kev siv los ntawm cov chaw tsim tshuaj paus.

Txais tos tej yam kev mob thiab dosing system

Thaum nws los txog rau noj tshuaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj, ncua, nws yog tsim nyog los siv nws tsuas yog tom qab ib tug noj mov. Nws yog ntshaw kom muaj dhau tsawg kawg yog 20 feeb tom qab haus, txwv tsis pub pharmacokinetic nyhuv ntawm nimesulide slows. Nrog kev xav txog cov txhais tau tias ntawm dosing thiab ntev ntawm kev kho mob, hais tias cov lus nug yuav tsum teb ncaj qha mus rau lub mus kawm tus kws kho mob noj mus rau hauv tus account tus neeg yam ntxwv ntawm tus neeg mob thiab cov neeg kawm ntawv ntawm tus kab mob heev. Yog li ntawd, peb xav txog xwb general tswv yim pom zoo, uas muaj cov lus qhia txog cov tshuaj "Nimid" phau ntawv qhia.

Ntsiav tshuaj raug neeg laus feem ntau ob zaug ib hnub twg nyob rau ntawm 100 mg. Rau hauv loj heev ntaub ntawv ntawm tus kab mob txhua txhua hnub koob tshuaj yuav tsum ob npaug. Cov me nyuam hluas ntawm 12 mus rau 18 xyoo pom zoo los mus laij lub koob ntawm cov tshuaj tus nqi ntawm 1.5 mg ib 1 kg lub cev hnyav. Yog hais tias kev kho mob yuav tsum tau los ntawm ib tug me nyuam uas yog nyob rau hauv lub hnub nyoog ntawm kaum ob, thiab nws hnyav tshaj 40 kg, nws yog tus kws kho 100 mg ntawm cov tshuaj ib hnub twg los mus faib rau tus nqi ntawm ob theem. Nyob rau hauv exceptional mob, tus kws kho mob tej zaum yuav ua rau kom cov pom zoo koob.

Txhais tau hais tias nyob rau hauv daim ntawv ntawm granules siv nyob rau hauv cov me nyuam los ntawm 12 xyoo thiab cov neeg laus: 1 sachet nyob rau hauv lub yav sawv ntxov thiab yav tsaus ntuj. Tus txheem ntawm lub hnab yog diluted nyob rau hauv 100 ml ntawm dej sov thiab haus tom qab noj mov.

Nrog kev xav txog cov gel "Nimid", nws - yog tsis ntau tshaj 4 lub sij hawm ib hnub twg - ib tug nyias txheej (tsis muab tshuaj ntxuav) nyob rau hauv lub cev feem nrog rau feem ntau mob heev. Tom qab siv cov tshuaj, ntxuav koj ob txhais tes nrog xab npum nyob rau hauv khiav dej.

Qhov no tshuaj yog txhob?

Tsis txhob muab tshuaj rau cov neeg uas peptic rwj kab mob, mob ua txhaum ntawm lub siab thiab ob lub raum, raws li tau zoo raws li hepatotoxic tshua rau nimesulide keeb kwm. Txaus txhob siv yeeb tshuaj nyob txawv xav rau los ntshav, mob insufficiency thiab npau taws me ntsis mus rau ib los yog ntau tshaj Cheebtsam ntawm lub medicament "Nimid Forte". Cov lus qhia rau kev siv thiab muaj cov lus qhia rau kev txwv tsis pub txoj kev siv cov nyiaj nyob rau hauv ua ke nrog nrog uas hepatotoxic tshuaj kub taub hau, mob npaws zoo li lub xeev thiab xav tias mob phais pathology.

Raws li rau cov nyiaj nyob rau hauv daim ntawv ntawm ib tug gel, nws tsis yog tshuaj rau cov neeg mob nyob rau hauv 12 lub xyoos ntawm hnub nyoog thiab cov neeg uas yog cov nquag mus tim tsis sib haum tshuaj loj. Exacerbate kab mob thaum lub sij hawm daim ntawv thov ntawm cov medicament yuav dermatitis, daim tawv nqaij raug mob thiab kab mob, raws li tau zoo raws li bronchial hawb pob, uas yog tshwm sim los ntawm ASA. Nws yog yog li ntawd tsis muab txhais tau tias "Nimid" nyob rau hauv lub saum toj no pathologies. Cov lus qhia rau kev siv cov ntsiav tshuaj nyob rau hauv xws li mob, dhau lawm, yog tsis pom zoo.

Kuv nqa cov tshuaj thaum lub sij hawm cev xeeb tub?

Lub zaum pom tias nisumelid tau muaj ib feem nyob rau fertility. Ntxiv mus, nws cheeb qhov uas cov synthesis ntawm prostaglandins, uas yog paub tias yuav tsum ua kom muaj oligohydramnios, pulmonary tawg, oliguria thiab ntxov ntxov narrowing Batalova ciav. Tej zaum ua rau kom txoj kev pheej hmoo ntawm weakening ntawm zog, ntawm peripheral edema thiab los ntshav thaum uas siv cov tshuaj "Nimid". Cov lus qhia rau kev siv, ntsiav tshuaj thiab lwm yam ntaub ntawv ntawm cov tshuaj yog txwv tsis pub ob leeg thaum lub sij hawm cev xeeb tub thiab thaum lub sij hawm lactation. Tom qab tag nrho, lub active tshuaj nrog lub mis mis nyuj yuav tau txais mus rau hauv tus me nyuam lub cev thiab cuam tshuam rau hauj lwm ntawm nws tseem ceeb heev systems. Nyob rau hauv cov mob uas nws yog tsis yooj yim sua ua tsis tau noj tshuaj, thiab kev pab rau cov niam ntau tshaj txoj kev pheej hmoo ntawm kev tsim txom rau tus me nyuam, ntau npaum thiab cov hoob kawm ntawm kev kho mob txiav txim los ntawm tus kws kho mob.

phiv

Tsis tas li ntawd zoo loj pharmacological yam ntxwv, cov kev npaj kuj muaj ib qho impressive daim ntawv teev cov kev phiv. Yog li ntawd cia saib dab tsi zoo ntawm cov tshuaj tiv thaiv yuav tshwm sim thaum koj siv lub "Nimid". Ntsiav tshuaj (qhia nyob rau hauv Lavxias teb sab ua rau cov ntaub ntawv muaj nyob) yuav ua rau khaus, ua xua, ntau yam daim tawv nqaij sawv pob, angioedema, thiab nyob rau hauv tej rooj plaub ntawm Stevens-Johnson syndrome thiab epidermal necrolysis. GI ua tau, nyob rau hauv lem, teb mus rau yeeb tshuaj los ntawm cem quav, raws plab, tej zaum cov neeg mob tej kev mob nyob rau hauv lub plab, xeev siab. Heev tsis tshua tshuaj yuav ua rau perforation ntawm lub rwj thiab peptic rwj thiab 12 duodenal rwj.

Txij li thaum tus txheej txheem ntawm cov metabolism hauv nyob rau hauv lub siab, nws kuj suffers los ntawm nws. Yog li ntawd, ntev-lub sij hawm siv tshuaj nyob rau hauv tej rooj plaub, yuav ua rau kev hloov nyob rau hauv transaminases, cholestasis, jaundice thiab txawm mob kab mob siab. Xws li irregularities nyob rau hauv lub siab yog tsis tau tsuas yog ntsiav tshuaj thiab granules thiab hmoov, tab sis "Nimid".

Ceeb toom uas qhia txog tau tshuaj tiv thaiv ntawm lub urogenital system nyob rau hauv cov tshuaj thawj coj. Nws yuav ua tau raws li edema, dysuria, urinary tuav, thiab oliguria, mob raum tsis ua hauj lwm, interstitial nephritis. Cov pa system tej zaum yuav dyspnea thiab bronchospasm, ntev siv yuav ua rau txoj kev loj hlob ntawm mob hawb pob.

Nyob rau hauv tas li ntawd mus rau cov teebmeem, tus neeg mob tej zaum yuav tsim tachycardia, tawg, hypothermia, qaug zog thiab lwm yam kab mob. Xyaum tag nrho cov kev phiv tshuaj yog pom zoo kom rho cov tshuaj thiab nrhiav tam sim ntawd kev kho mob. Yuav kom tsis muaj nyob rau hauv qhov teeb meem no, koj yuav tsum ua tib zoo xyuas tag nrho cov tau cov lus qhia txog cov tshuaj thiab ces coj "Nimid Forte" (ntsiav tshuaj). Cov lus qhia rau kev siv, uas yog nyob rau hauv txhua pob tshuaj yuav pab tau.

Overdose ntawm siv yeeb tshuaj thiab kev xub pab algorithm

Yog hais tias koj ntawd ntau tshaj qhov pub koob tshuaj, yuav tsum tam sim ntawd mus rau lub tsev kho mob. Tom qab tag nrho, qhov tshwm sim ntawm tej kev ua yuam kev ib qho yuav ua tau nkees nkees, xeev siab, ntuav, mob nyob rau hauv espigastrii, nkees, nce ntshav siab. Qhov no yog ib daim ntawv teev cov xwb lub teeb kev tshua mus rau lub siab dua koob ntawm cov tshuaj "Nimid". Ntsiav tshuaj - phau ntawv ceeb toom txog qhov no - coj nyob rau hauv ib tug npaum li ntawm 2-3 daim ntau tshaj li qhov tso cai tus nqi, yuav ua tau nrog los ntshav thiab ua rau lub raum tsis ua hauj lwm. Nyob rau hauv kev kho mob xyaum, txawm tas tsawg tus neeg mob anaphylactoid tshua, ua pa nyuaj siab thiab coma vim overdose ntawm cov tshuaj no.

Yog hais tias peb yog permissible koob tshuaj yog ua zoo tshaj, tos rau tus soj ntsuam ces yog tsis nqi nws. Koj yuav tsum tau sai li sai tau ntxuav tawm lub plab, coj cov osmotic laxative thiab chelators. Dua li tom qab lub saum toj no kev ntsuas mus rau lub tsev kho mob, qhov chaw uas tshwj xeeb yuav muaj mus ntxiv rau symptomatic kev kho mob. Nws yuav tsum tau muab sau tseg hais tias rau hnub tim muaj tsis muaj ib yam tshuaj.

Dab tsi ua lawv xav txog cov tshuaj rau cov neeg mob?

Ntawm cov hoob kawm, nyob rau hauv cov kab mob mob mob yuav luag tag nrho cov neeg teb zoo mus rau lub xam tau tias yog tshuaj. Lawv nco ntsoov tias cov teebmeem ntawm cov tshuaj siv tshwm sim haum sai sai, uas tsis tau tab sis kev zoo siab. Heev lwm yam lus muaj peev xwm yuav hnov thaum tus neeg mob tau muab ib tug ntev chav kawm ntawm cov tshuaj kho, "Nimid". Ntsiav tshuaj (phau ntawv xav kom tshwj xeeb mloog mus no pharmacological khoom teejtug uas yog cov tshuaj) sai daws mob, tab sis tom qab ib tug ob peb hnub ntawm kev txais tos ua rau lawv tus kheej lub npe hu phiv. Tus thawj pib hnov mob rau nimesulide mob huam, lub paj hlwb tom qab ntawd (qhov no yog manifested los ntawm txob taus, mus ob peb vas ua viav vias thiab ib tug ib txwm mus apathy).

Ntawm cov hoob kawm, categorically hais tias cov tshuaj tsim kev mob ntau tshaj kev zoo, nws yog tsis yooj yim sua. Tom qab tag nrho, nws yeej yuav pab. Tab sis ntawm no yog coj tsis tau cov pov thawj thiab lo lus uas peb cov kws yog tsis pom zoo.

Yog hais tias saum toj no cov lus qhia nyob rau hauv tsis ntseeg seb puas los yog tsis mus yuav "Nimid" (ntsiav tshuaj), cov lus qhia, xyuas, thiab tswv yim tus neeg mob tus kws kho mob yuav pab tau kom txoj kev txiav txim.