Folic acid: phiv, yuav ua li cas coj

Cev xeeb tub rau txhua txhua tus poj niam - ib tug tseem ceeb heev lub sij hawm ntawm lub neej. Thiab lub luag hauj lwm ntawm cov vitamins B nyob rau hauv txoj kev loj hlob ntawm lub fetus yog tseem ceeb heev. Lawv yog cov tsim nyog rau lub qub tsim ntawm lub paj hlwb thiab lwm yam systems, cell division, tus txheej txheem ntawm hematopoiesis thiab ib tug qub embryo txoj kev loj hlob. Yog li ntawd nws yog ib qho tseem ceeb heev ua ntej cev xeeb tub yuav tau noj cov tshuaj no raws li "folic acid". Sab los, xyuas thiab tag nrho cov yam ntxwv ntawm cov hais tias daim ntawv thov txhais tau tias peb yuav them tom qab nyob rau hauv no tsab xov xwm.

cov ntaub ntawv

Folic acid - ib tug dej-soluble vitamin B9. Nws twb xub tshwm sim nyob rau hauv lub 30s ntawm lub xeem caug xyoo. Thiab cov tho kev pib Mehta thiab Wills. Qhov no discovery tau raug hu ua "qhov zoo tshaj yuav Log" raws li zoo raws li lub txais tos hu ua vitamin pab nyob rau hauv cov kev kho mob ntawm anemia nyob rau hauv cev xeeb tub cov poj niam. Ib me ntsis tom qab, zaum twb tau txais cov vitamin los ntawm spinach nplooj, ces nws tau txais lub npe "folic acid".

Tshwm sim los ntawm cov tshuaj yeeb dej caw tsis tau, tab sis, ntawm chav kawm, muab nws yuav tsum tsis txhob yuav uncontrolled. Biologically tsaug zog folic acid nkag mus rau hauv lub cev, ntawm nws cov cell yog hloov dua siab tshiab rau nws cov active daim ntawv - tetrahydrofolic acid, uas yog suav hais tias yog lub hauv paus rau cov tsim ntawm DNA thiab RNA.

Nws yog qhov tseem ceeb rau lub qub maturation thiab normoblasts megaloblasts, koom nyob rau hauv lub synthesis ntawm cov amino acids, nucleic acids, choline metabolism, purine thiab pyrimidine. Thiab thaum lub sij hawm cev xeeb tub kom tsawg ntawm cov tshuaj yeeb dej caw los tiv thaiv ib tug poj niam lub cev thiab lub fetus los ntawm raug teratogens.

Ib zaug nyob rau hauv lub plab, acid yog sai absorbed muaj. Hloov Siab Los Ntseeg rau hauv metabolites nyob rau hauv lub siab. Tso tawm nrog rau cov zis. Phiv los ntawm folic acid feem ntau tsim nyob rau hauv daim ntawv ntawm cov kev tsis haum tshuaj loj.

Piav ib yam khoom uas nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj thiab tsiav tshuaj, haum rau tau txais raws li zoo raws li ib feem ntawm ib tug plurality ntawm cov tshuaj thiab noj tshuaj pab.

Indications thiab contraindications

Folic acid ntsiav tshuaj raug rau anemia tshwm sim los ntawm tsis muaj kev hais tias tshuaj nyob rau hauv lub cev, raws li zoo raws li lub Cheebtsam ntawm lub ua ke txoj kev kho:

• mob Gastroenteritis;
• plab hnyuv kab mob ntsws;
• rau kev tiv thaiv ntawm neural raj malformations nyob rau hauv lub fetus thaum lub sij hawm thawj peb lub hlis uas cev xeeb tub;
• nrog sprue.

Folic acid yog txhob yog ib tug neeg mob muaj yog ib tug npau taws me ntsis rau nws zoo li:

• nyob rau hauv ua cancer hlav;
• gemosideroze;
• txhaum ntawm cov hlau metabolism;
• nyob rau hauv tus neeg mob ntawm cobalamin tsis muaj peev xwm;
• malabsorption ntawm vitamin B12.

ntau npaum

Folic acid npaj yog feem ntau zoo taus, thiab overdose tsis tshua cai. Cov tshuaj nyob rau hauv lub hnub nyoog ntawm tus neeg mob thiab kab mob heev. Piv txwv li, ib tug neeg laus ib hnub yog tshuaj kev txiav txim ntawm 200 ug, cev xeeb tub - 300-400 g thiab laus - 500 micrograms. Duration ntawm kev kho yog feem ntau ib lub hlis.

Cov me nyuam mos txhais tau hais tias yog muab nyob rau hauv ib tug qis koob tshuaj - los ntawm 40 mus 200 mg, nyob ntawm seb tus mob. Nyob rau hauv tej rooj plaub, cov tshuaj "Folic acid" phiv nyob rau hauv cov me nyuam yuav manifest li ua pob ua xyua thiab khaus ntawm daim tawv nqaij.

Nyob rau hauv thiaj li yuav coj tiv thaiv medicament tus nqi ntawm 20 los yog 50 micrograms ib hnub twg.

tshuaj cov kev sib tshuam

Dua li ntawm qhov virtual tsis tuaj kawm ntawv ntawm cov kev phiv yuav tsum tseem ua raws li tej yam kev cai nyob rau hauv daim ntawv thov ntawm "Folic acid" ntsiav tshuaj. Yog li ntawd, nws yog tsis pom zoo kom siv sij hawm nrog lawv cov nram qab no cov tshuaj:

• qhov ncauj contraceptives;
• "Sulfasalazine";
• "Phenytoin";
• "Phenobarbital";
• "Primidone".

Raws li twb tau hais, nyob rau hauv feem ntau cov tshuaj tiv taus, tab sis tej zaum kuj yuav tshwm sim kev tsis haum tshuaj xws li mob ua pob xua thiab liab ntawm daim tawv nqaij. Yog hais tias koj muaj kev cov tsos mob no, mus nrhiav kev pab kho mob. Nws tso tseg cov tshuaj thiab muab symptomatic kev kho mob.

Tej zaum cov kev phiv los ntawm folic acid thaum lub sij hawm cev xeeb tub yuav cuam tshuam ib tug poj niam nyob rau hauv daim ntawv ntawm thaum sawv ntxov kev mob kev nkeeg, insomnia thiab muaj zog txob taus. Ib tug mob thawj coj uas muaj zog koob tshuaj ntawm cov tshuaj yuav ua rau mob plab, ua txhaum ntawm lub rooj zaum thiab txawm qaug dab peg.

ceev faj

Thaum lub sij hawm txais tos npaj muaj folic acid, nws yuav tsum tau nco ntsoov tias twb nyob rau hauv txaus ntshai tshaj anemia noj tshuaj xwb yuav tsum vitamin B12, vim hais tias acid nkoos hematopoiesis thiab tsis tiv thaiv kom txhob loj hlob ntawm cov teeb meem ntawm poob siab system. Dhau sij hawm ntev siv acid tej zaum yuav ua ib tug txo nyob rau hauv cov ntshav cyanocobalamin.

Los ntawm txoj kev, piav acid tej zaum kuj yuav muab rau cov neeg sawv cev ntawm lub zog txiv neej pw. Yog hais tias tus txiv neej cov phev muaj tsis txaus los yog ntev npaum li cas ntawm chromosomes, nws yuav kuaj raws li "aneuploidy". Feem ntau cov feem ntau, nws ua ib tug ua ntawm cov txiv neej ntxiv lawm tshob. Txo txoj kev pheej hmoo ntawm kev tsim tus kab mob no yuav kho tau "Folic acid".

Sab los nyob rau hauv cov txiv neej, los ntawm txoj kev, tshwm sim nyob rau hauv tsawg tus neeg mob, raws li ib tug txoj cai, khaus ntawm daim tawv nqaij.

Tshuaj "Folacin"

Peb yuav tsum piav qhia txog nyias npaj muaj folic acid. Yog li, "Folacin" yog hais txog cov pab pawg neeg ntawm cov vitamins thiab yog pom nyob rau hauv daim ntawv ntawm cov daj cov ntsiav tshuaj uas muaj 5 mg vitamin B9. Qhov no yog ntau tshaj txhua hnub koob tshuaj rau cev xeeb tub cov poj niam, tab sis qhov tshaj yam khoom uas yog tas nyob rau hauv cov zis.

Siv cov tshuaj nyob rau hauv cov ntaub ntawv ntawm kev mob loj vitamin tsis muaj peev xwm hu, tab sis los mus tiv thaiv nws yog tsis pom zoo kom noj.

Hu ntsiav tshuaj nkoos erythropoiesis, synthesis ntawm cov amino acids thiab choline pauv. Thaum lub sij hawm uas cev xeeb tub, cov tshuaj tiv thaiv lub fetus los ntawm qhov teeb meem los ntawm qhov chaw, yeej txhawb ib txwm loj hlob thiab maturation ntawm lub tsho me nyuam. Nws tseem pab tau mus kho thiab thaum lub sij hawm pub niam mis. Cov tshwm sim los ntawm folic acid nyob rau hauv cov kev npaj "Folacin" nyob rau hauv feem ntau tus neeg mob, tsis muaj.

Indications thiab contraindications

"Folacin" yuav raug muab tso nyob rau hauv cov nram no mob:

• kev kho mob ntawm mob folate tsis muaj peev xwm txuam nrog malnutrition;
• kev kho mob rau anemia, uas provoked drawback ntawm hais tias tshuaj nyob rau hauv lub cev;
• kev kho mob ntawm anemia thaum lub sij hawm lub hnub los yog lactation;
• tiv thaiv kom txhob txawv txav kev loj hlob ntawm lub neural raj nyob rau hauv lub fetus nyob rau hauv lub plab;
• long-term kev kho mob nrog cov tshuaj, uas yog folic acid antagonists.

Raws li twb tau hais, yuav tsum tau teem cov neeg ua hauj, uas muaj folic acid thaum lub sij hawm cev xeeb tub. Sab los (zoo li cas thiab yuav ua li cas rau manifest lawv tus kheej) los ntawm lawv cov kev txais neeg kawm yuav tsum tau txais los ntawm koj tus kws kho mob. Contraindications, raws li ib tug txoj cai, yog:

• ntau yam malignancies;
• cobalamin tsis muaj peev xwm;
• pernicious anemia;
• Npau taws me ntsis mus rau yeeb tshuaj.

Cov tshuaj ntawm cov tshuaj "Folacin"

"Folacin" yog muab hais lus. Cov ntsiav tshuaj yuav tsum tau muab faib. Rau cov kev kho mob ntawm tag nrho cov hom ntawm anemia uas yog txuam nrog rau folic acid deficiency, ib tug yeeb tshuaj noj ib koob tshuaj 5 mg ib zaug ib hnub twg. Duration ntawm kev kho yog 4 lub hlis. Nyob rau hauv inflammatory dab nyob rau hauv cov nyuv thiab qhov tshuaj no yog dosed malnutrition mus rau 15 mg ib hnub twg.

Rau kev tiv thaiv ntawm neural raj txawv txav nyob rau hauv lub fetus ua ntej cev xeeb tub yam khoom uas yog noj ib koob tshuaj ntawm 2.5 mg ib hnub twg rau ib lub hlis. Ntsiav tshuaj thiab ncua nyob rau hauv thawj peb lub hlis ntawm hnub.

Sis nrog lwm yam tshuaj

Tsis muaj cai faib cov tshuaj noj hauv qab no txhais tau tias:

• "Chloramphenicol";
• "Neomycin";
• "Polymyxin";
• "Tetracycline";
• "Cycloserine";
• "Phenobarbital";
• "Primidone";
• "Cholestyramine".

Ua ntej kev kho mob yog tsim nyog los xav txog yuav ua li cas nws yuav teb mus rau ib tug kev tshuaj folic acid. Sab los (xeev siab, tawv nqaij sawv pob) sawv li, tej zaum yuav qhia tau tias cov tshuaj yog coj kom zoo.

Tshuaj "Mamifol"

Tom ntej no medicament muaj folic acid belongs rau cov pab pawg neeg ntawm vitamin npaj. Nws yog muaj nyob rau hauv daim ntawv ntawm cov dawb ntsiav tshuaj. Cov kev npaj muaj xws li ib tug folic acid koob tshuaj 0.4 mg.

Siv cov synthesis ntawm hais tias txhais tau hais tias yog hloov kho amino acid methionine, uas yog tsis hnov nyob rau hauv expectant niam. Yog li ntawd, lawv yuav tsum thaum lub sij hawm cev xeeb tub nyob rau hauv thaum ntxov ua sawv mus pib noj "Mamifol", nyob rau hauv uas muaj yog folic acid. Sab los ntawm kev siv ntawm - kev tsis haum tshuaj, pruritus, erythema, thiab bronchospasm. Tab sis lawv tsim ntau heev.

Indications thiab contraindications

Hais tias kev npaj yuav siv nyob rau hauv cov neeg mob:

• anemia tshwm sim los ntawm folic acid deficiency;
• rau kev tiv thaiv ntawm neural raj tsis xws luag nyob rau hauv lub fetus.

Contraindications rau kev siv yog:

• cobalamin tsis muaj peev xwm;
• mob malignancy;
• pernicious anemia;
• nyiam los tsim kev tsis haum tshuaj loj.

ntau npaum

Cov tshuaj yog muab ib ntsiav tshuaj ua ntej npaj cev xeeb tub nyob rau hauv thawj peb lub hlis thiab tom qab nws tshwm sim. Hoob no ntawm kev kho mob yog ib lub hlis.

Nws yog coj lus ua ntej noj mov, dua li nyob rau hauv thaum sawv ntxov. Cov tshuaj yuav tau nce yog hais tias tus neeg mob muaj siab folate tsis muaj peev xwm thiab anemia pib.

overdose

Kev npaj "Mamifol" zoo taus nyob rau hauv koob tshuaj mus txog rau 5 mg ib hnub twg. Ib tug ntau dua concentration tej zaum yuav ua rau cov nram qab no tshwm sim tsis zoo:

• mob ntawm lub hauv paus poob siab system ntawm kev ua hauj lwm;
• tsis ua hauj lwm ntawm lub plab thiab cov hnyuv.

Kom tsis txhob overdose, nws yuav tsum zoo noj cov tshuaj uas muaj folic acid. Sab los feem ntau ploj tom qab ib tug ob peb hnub tom qab txhaj koob tshuaj haum.

Sis nrog lwm yam tshuaj

Tsis txhob noj cov tshuaj "Mamifol" nrog rau cov nram qab no txhais tau tias:

• "Monotreksat";
• "Sulfasalazine";
• qhov ncauj contraceptives.

Tshuaj tiv thaiv, qaug dabpeg, on qhov tsis tooj, ua rau kom qhov yuav tsum tau rau folic acid.

Nyob rau hauv tsawg tus neeg mob, cov nram qab no tshwm sim tsim nyob rau hauv lub chav kawm ntawm kev kho:

• kev tsis haum tshuaj, manifested raws li ib tug pob, lossis puas liab liab ntawm daim tawv nqaij;
• flatulence;
• xeev siab;
• epigastric mob;
• pw tsaug zog teeb;
• ntxhov siab vim.

Nyob rau tshwm sim ntawm tej tsis kaj siab tsos mob yuav tsum qhia rau koj tus kws kho mob.

ceev faj

Khaws cov tshuaj raws li rau folic acid yog tsim nyog rau ib kub tsis muaj siab tshaj 30 degrees tawm ntawm ncav cuag ntawm cov me nyuam tsawg tshaj li ob lub xyoos. Cov tshuaj muaj pes tsawg leeg muaj xws li lactose, yog li ntawd lawv yuav tsis tau los siv rau cov neeg mob uas muaj raws roj ntsha mob assimilation daim ntawv ntawm cov tshuaj yeeb dej caw.

Raws li pom los ntawm cov saum toj no, cov kev phiv los ntawm folic acid yog heev tsawg, thiab lawv feem ntau tsim thaum zoo xaiv ntau npaum. Yog li ntawd ua ntej rau kev kho mob koj yuav tsum ua tib zoo nyeem cov lus qhia rau kev siv, uas qhia txog nyob rau hauv kom meej tag nrho cov indications thiab contraindications rau lub cuab tam, thiab tshwj xeeb tshaj yog nws txais tos.

Nws yog ib qho tseem ceeb yuav tau nco ntsoov yog tias tsuas yog ib tug kws kho mob yuav muab tshuaj thiab nws cov tshuaj teeb. Self-tshuaj yuav ua rau loj txim. Los ntawm txoj kev, tom qab qhov kawg ntawm lub neej ntawm cov ntsiav tshuaj yuav tsum tsis txhob coj raws li cov kev tsis saib xyuas ntawm lub tswv yim pom zoo tej zaum yuav ua rau loj lom.

Folic acid yog ib qho tseem ceeb heev luag hauj lwm nyob rau hauv lub qub hauj lwm ntawm lub cev, ces koj yuav tsum tau pib noj tshuaj, ib feem ntawm uas cov tivthaiv yog muaj txaus noj haus, qhov kev nyuaj siab. Tsis txhob hnov qab coj tshuaj thaum lub sij hawm cev xeeb tub. Qhov no yuav ua rau kom txoj kev yug me nyuam ntawm ib tug noj qab nyob zoo tus me nyuam.