"Estrozhel": cov lus qhia rau kev siv, ib tug piav qhia ntawm cov kev npaj, analogs, phiv

Nws yog tsis muaj daim card uas rau lub climacteric syndrome yus muaj los ntawm autonomic-leeg tshav, puas siab puas ntsws thiab metabolic thiab endocrine ntshawv siab uas tshwm sim los ntawm lub fairer nrog txiv neej pw nrog ib tug tag nrho cov muaj hnub nyoog involution ntawm tus kab mob, raws li tau zoo raws li nyob rau hauv lub keeb kwm yav dhau ntawm lub tsheb txhob sibtsoo extinction ntawm hormonal ntawm zes qe menyuam muaj nuj nqi.

Nyob rau hauv no nyuaj lub sij hawm rau cov poj niam lawv tsis tu ncua xav tias kub flushes mus rau lub taub hau, lub cev thiab tej caj npab.

Nyob rau hauv tas li ntawd, cov tsos mob lawm, xws li ntev li txob taus, insomnia, kev nyuaj siab, tsis muaj zog thiab zoo nkaus li qhov ntshai. Feem ntau, cov fairer nrog txiv neej pw hloov qab los noj mov cuam tshuam migraine, kiv tauv hau, raws li zoo raws li muaj tawm fws, edema thiab vasospasm.

Yuav kom tsis muaj kev txhawj tus poj niam tus mob, cov tshuaj tuam txhab uas muag pib tsim protivoklimaktericheskie tshuaj. Qhov zoo tshaj ntawm no muaj xws li xws cov tshuaj raws li "Estrozhel". Xyuas (thaum lub sij hawm lawm yog qhov txhais tau tias tus kws kho ntau heev) cov neeg siv yuav tsum hais hauv qab no. Koj kuj yuav tau kawm yuav ua li cas siv lub hais tias cov tshuaj, ntau npaum li cas nws cov nqi, thiab hais txog.

Hauj lwm, muaj pes tsawg leeg, ntim thiab tso tawm daim ntawv

muag cov tshuaj "Estrozhel" Nyob rau hauv dab tsi daim ntawv no? Xyuas ntawm cov poj niam lub xeev uas ib tug yeeb tshuaj muaj peev xwm yuav nrhiav tau nyob rau hauv daim ntawv ntawm ib tug transdermal gel. Nws yog tsis muaj kob, pob tshab, thiab muaj tus ntxhiab tsw ntawm ethanol.

Lub active ingredient ntawm no neeg sawv cev ua estradiol. Raws li koom haum pab khoom xyaw medicament muaj carbomer, ethanol, trolamine thiab lim dej.

Kev npaj "Estrozhel" (gel) yog muag nyob rau hauv cov hlab ntawm txhuas. Tseem tau sau yog ib tug tshwj xeeb applicator rau dispensing.

pharmacological nta

Yuav ua li cas yog ib tug gel "Estrozhel"? Cov lus qhia nyob rau hauv daim ntawv thov hais tias nws yog ib tug hormonal neeg sawv cev, uas ua rau tus tsis muaj tshuaj nyob rau hauv ib tug poj niam lub cev.

Tsaug rau nws cov active cov khoom xyaw tshuaj no muaj estrogenic kev ua si. Nws yog npaj rau lwm los pleev daim ntawv thov.

Nyob rau hauv cov kev kho mob ntawm lub tsev no nyob rau hauv lub fairer poj niam txiv ho txo cov tsos mob ntawm menopausal syndrome, xws li kev nyuaj siab, tawm pob, kub flushes thiab paum dryness.

Nyob rau hauv nws cov kev soj ntsuam ua hauj lwm zoo nyob rau hauv cov kev kho mob ntawm postmenopausal cov tsos mob pom tias cov tshuaj tsis zam kev rau kev kho mob nrog qhov ncauj tshuaj kho. Ntxiv mus, thaum uas siv cov cuab tam nyob rau hauv menopausal cov neeg mob cim slowing ntawm dab uas txo cov kev ceev ntawm lub pob txha cov ntaub so ntswg.

Tsis tas li ntawd siv txoj kev kho yuav pab txo tag nrho cov roj uas txhaws.

Peb tsis tau hais tias cov tshuaj "Estrozhel", tus nqi ntawm uas yog qhia hauv qab no, muaj procoagulant efficiency. Nws thiaj li tus nqi ntawm cov antithrombin III thiab tsub kom hepatic synthesis ntawm K-dependent ntshav nrog.

pharmacokinetic zog

Seb tshuaj yog absorbed "Estrozhel"? Xyuas cov kws txawj hais tias tom qab daim ntawv thov ntawm cov gel tshwm sim heev sai evaporating lub ethanol, uas estradiol tam sim ntawd penetrates ntawm daim tawv nqaij. Ib tug loj ib feem ntawm cov tshuaj sai li sai tau nkag mus rau hauv mauj kev, thiab me me - yog muab khaws cia tseg nyob rau hauv lub subcutaneous rog, uas yog tseem tso maj mam.

Tom qab lub zos siv cov gel nyiaj pab ntau tshaj concentration ntawm estradiol nyob rau hauv cov ntshav cai tom qab 180-240 feeb. Lub bioavailability ntawm cov tshuaj yog 82%.

Saib medicament yog tsis raug rau cov nyhuv ntawm "thawj pass", uas yuav muab ib tug ntau dua ntshav concentration ntawm estradiol nyob rau hauv kev sib piv nrog qhov ncauj analogues.

Tshem ntawm estradiol thiab nws metabolic transformation piv rau cov neeg rau tib lub ntuj cov tshuaj no.

Indications rau daim ntawv thov ntawm ib tug sab nraud npaj

Vim li cas cov tshuaj "Estrozhel" yuav siv tau? Cov lus qhia rau kev siv qhia hais tias qhov no tshuaj yog pom zoo kom txo los yog tshem tawm cov tsos mob ntawm lub climacteric syndrome, xws li artificially ntxias lawm. Nyob rau hauv tas li ntawd, cov tshuaj nyob rau hauv lo lus nug yog feem ntau siv rau kev tiv thaiv thiab kev kho mob ntawm kab mob thaum lub sij hawm lawm.

Contraindications

Yog koj paub txog thaum twg koj yuav tsum tsis txhob siv cov gel "Estrozhel"? Cov lus qhia rau kev siv qhia tias mus rau lub tsis contraindications ntawm no lub cuab tam muaj xws li cov nram qab no tej yam kev mob:

• Rotor syndrome;
• ischemic los yog haemorrhagic stroke;
• mob thrombophlebitis los yog thromboembolism;
• thaum lub sij hawm cev xeeb tub;
• uterine los ntshav ntawm undetermined keeb kwm;
• raum tsis ua hauj lwm;
• Kev pub niam mis;

• ; Johnson - syndrome Dubin
• tshuaj-dependent malignancies los yog lub sijhawm twg los ntawm lawv xub ntiag;
• npau taws me ntsis;
• benign los yog phem hlav ntawm lub pituitary;
• Loj siab tus kab mob nyob rau hauv lub mob theem, siab hlav, thiab daj ntseg.

Ceev faj siv ntawm lub medicament

Thaum twg kuv thov lub gel "Estrozhel" nrog huab ceev faj? Guest kws txawj hais txog cov nram qab no tej yam kev mob:

• leiomyoma;
• coronary artery kab mob;
• endometriosis;
• teeb ntawm daim siab kev ua;
• pancreatitis;
• mob ntshav qab zib;
• migraine;
• qaug dab peg;
• mob hawb pob;
• tsev neeg hyperlipoproteinemia;
• hepatic porphyria;
• inflammatory kab mob ntawm lub tsev me nyuam nyob rau hauv lub fairer nrog txiv neej pw;
• cai ua ntej daj ntseg, nrog rau nws cov manifestation nyob rau hauv lub chav kawm ntawm lub xeem uas cev xeeb tub;
• trombozay, thrombophlebitis los yog thromboembolism (piv rau cov tshuaj no kho mob);
• tawg nyob rau hauv mob loj heev;
• pathology gallbladder thiab cholelithiasis (keeb kwm);
• hypercalcemia txuam nrog cov pob txha metastases ntawm cov kua ntswg nyob rau hauv hlav;
• lub plawv mob.

Gel "Estrozhel": cov lus qhia rau kev siv

Saib npaj tsuas yog siv topically. Nyob rau hauv cov ntaub ntawv no nws yog siv tsis tu ncua los yog cyclically. Duration ntawm kev kho mob thiab ntau npaum ntawm cov tshuaj yog xaiv ib lub zuj zus.

Ib koob tshuaj gel "Estrozhel" (2.5 g) muaj 1.5 mg ntawm estradiol.

Nyob rau hauv cov kev kho mob ntawm cov tsos mob lawm qhia pov tseg ua ntawv thov cov tshuaj ib hnub twg nyob rau hauv ib tug npaum li ib koob tshuaj. Cov gel twb thinly kis tshaj ntawm daim tawv nqaij nyob rau hauv lub cheeb tsam ntawm lub lumbar cheeb tsam, forearm, plab los yog xub pwg, thiab tos nws tsis xuas.

Lub tsev kawm ntawv ntawm daim tawv nqaij qhov twg cov tshuaj tau ua ntawv thov, yuav tsum tsis txhob yuav tsawg tshaj li qhov chaw ntawd ntawm ob txhais tes ntawm cov neeg mob.

Rau qhov tseeb kev ua tau zoo ntawm daim ntaub ntawv nrog qhov zoo tshaj tshwm sim yog tsiag ntawv los ntawm haum ntawm cov tshuaj nyob rau hauv 3 feeb. Nyob rau tib lub sij hawm lub preservation ntawm stickiness tom qab daim ntawv thov ntawm ib tug tib koob tshuaj ntawm cov tshuaj rau 5 feeb qhia ib tug tsis muaj chaw siv los ntawm daim tawv nqaij.

Thov cov tshuaj yuav tsum tus neeg mob (thaum sawv ntxov los yog yav tsaus ntuj). Thov lub gel yog ntshaw kom yav tas los ntxuav npog.

phiv

Yuav ua li cas yog cov pliaj los tshwm sim tom qab siv cov "Estrozhel" gel? Xyuas ntawm cov poj niam qhia phiv:

• daim tawv nqaij voos, daim tawv nqaij yaug kais dej, mob taub hau thiab yastes yastaw;
• mus ob peb vas viav vias, thiab kiv taub hau;
• rhiab heev thiab nce nyob rau hauv loj ntawm lub mammary qog, lawv mob, menorrhagia, amenorrhea, txhob los ntshav;
• hlav nyob rau hauv lub mammary qog, nce libido, smearing paum paug, nrog rau intermenstrual sij hawm;
• kem plab, tsib lub zais zis thaiv, xeev siab, ntuav, kab mob siab, epigastric mob, anorexia, pancreatitis;
• cholelithiasis, cholestatic daj ntseg, raws plab, mob plab, tu-sauv, tsam plab;
• thromboembolism, hu rau lens intolerance, qhov hnyav kev hloov, peripheral edema;
• nce ntshav siab, tsis haum tshuaj loj (xws li urticaria thiab khaus ntawm daim tawv nqaij), hu rau dermatitis.

Tag nrho cov sab los yog qhia es weakly. Lawv feem ntau yog tshwm sim nyob rau hauv thaum ntxov ua sawv ntawm txoj kev kho thiab luag yeej tsis yuav tsum tau discontinuation ntawm cov tshuaj.

tsos mob ntawm overdose

Yuav ua li cas yuav tshwm sim thaum ib tug loj npaum li cas ntawm cov tshuaj "Estrozhel" (yuav ua li cas mus thov qhov cuab tam, peb tau hais rau saum toj no)? Nyob rau hauv cov ntaub ntawv ntawm ntau dua koob tshuaj ntawm cov medicament nyob rau hauv tus neeg mob xeev siab thiab ntuav, raws li zoo raws li tsim uterine los ntshav. Nyob rau hauv lub tsim ntawm cov tsos mob no siv lub gel tam sim ntawd nres.

Sis nrog lwm yam tshuaj

Yog nws tau mus ua ke nrog lwm yam tshuaj tshuaj "Estrozhel" (gel)?

• Nyob rau hauv thaum uas tig mus daim ntawv thov ntawm antihypertensive thiab hypoglycemic sawv cev, thiab anticoagulants tej zaum yuav txo lawv cov hauj lwm zoo, uas yuav tsum tau ib tug saib xyuas ntawm lub dosing regime.
• Lub ua ke ntawm "Estrozhelya" thiab lipid tej tshuaj leads mus rau ib nce nyhuv ntawm lub yav tas.
• Nrog simultaneous siv rau cov tshuaj uas yog inducers ntawm microsomal siab enzymes (e.g., "rifamycins", "Carbamazepine", "griseofulvin" thiab barbiturates), ntshav estradiol yuav txo tau.
• Kev siv cov gel thiaj li cov hauj lwm zoo ntawm diuretics thiab txiv neej nrog txiv neej pw cov tshuaj hormones.
• Lub simultaneous siv ntawm cov tshuaj, opioid analgesics thiab tshuaj siv rau kev tshuaj loog, accelerates metabolism ntawm estradiol.
• Ua ke nrog uas muaj tej yam tshuaj tua kab mob (xws li "Rifampicin" thiab "ampicillin"), raws li zoo raws li "phenylbutazone" thiaj li ntshav ntau ntawm estradiol.
• Tib mus kho mob nrog folic acid thiab cov thyroid hormones tsub kom lub estradiol los txhais tau tias.

tej tswv yim pom zoo

Tshuaj "Estrozhel" siv yog txwv tsis pub lub sij hawm uas cev xeeb tub. Nws yuav tsum tau muab sau tseg tias ua ntej daim ntawv thov ntawm cov gel cov poj niam yuav tsum yuav tsum tau txais ib tug tag nrho gynecological xeem. Nrog ntev-lub sij hawm kev siv ntawm cov tshuaj, xws cov txheej txheem yuav tsum tau nqa tawm yam tsawg ib xyoos ib zaug.

Raws li cov tswv yim ib tug kws kho mob yog advantageously nqa tawm nyob rau hauv ua ke nrog nrog estradiol, progestin txoj kev kho. Xws li ib tug ua ke yuav tiv thaiv cov endometrium.

Nws yuav tsum tiv thaiv lub mucosa ntawm chaw mos thiab koj qhov chaw mos, raws li zoo raws li cov tawv nqaij nyob rau hauv lub mis los ntawm tau txais nyob rau lawv pom tau hais tias cov tshuaj.

Heev siv ntawm cov tshuaj, xws li siab koob, tsub kom qhov uas yuav ntawm ob lub mis thiab endometrial cancer.

Yog hais tias koj xav mus ua kev tuamyeem phais, cov tshuaj no txoj kev kho yuav tsum tau txiav rau 4-6 lub lis piam ua ntej.

"Estrozhel" yuav tsum tsis txhob muab siv thaum lub sij hawm cev xeeb tub npaj. Nws yuav tsum tau muab sau tseg tias cov active medicament tsis contraceptive zog thiab tsis tiv thaiv kom txhob conception.

Tshuaj "Estrozhel" thiab "Utrozhestan" - ib tug zoo meej ua ke. Vim qhov no yog qhov zoo tshaj ntawm tus neeg mob lub neej thaum lub sij hawm lawm ho zoo tuaj.

Nqi thiab zoo sib xws npaj

Yuav ua li cas npaum li cas yog ib tug gel "Estrozhel"? Tus nqi ntawm no neeg sawv cev yog hais txog 700 rubles. Yog hais tias yuav tsum tau, nws yuav tsum tau hloov los ntawm lwm yam tshuaj xws li "Estrokad", "Esterlan", "Estrovagin", "Ovestin", "Sinestrol", "Kolpotrofin", "ethinylestradiol", "Elvagin", "Ovipol Clio", "Pauzogest "," Klim "thiab lwm tus neeg.

Xyuas cov poj niam

Lub fairer nrog txiv neej pw siv ib tug txhais tau rau cov nyem ntawm menopausal cov tsos mob, tawm hauv nws tsuas zoo lub tswv yim. Lawv nco ntsoov nws cov high efficiency thiab ib tug me me zaus thiab qhov ntawm cov kev phiv piv nrog qhov ncauj counterparts.

Lwm yam zoo zoo ntawm cov tshuaj muaj xws li nws yooj yim dosing mechanism, cov tsis muaj tackiness tom qab tus txheej txheem thiab lub ceev ceev haum mus rau hauv daim tawv nqaij.