Cov tshuaj 'tamoxifen'. Instruction nyeem ntawv

Cov tshuaj "Vero tamoxifen" yog siv rau ib tug ntev lub sij hawm. Cov tshuaj no yog dej num raws li xim estrogen receptor modulators. Tshuaj tau txais mus rau hauv cov hlab ntsha, faib thoob plaws hauv lub cev.

Vim lub fact tias cov txhais tau tias "tamoxifen" muaj negligible estrogenic kev ua si, nws muaj ib tug heev muaj zog stimulatory ntxim rau lub hlwb. Muaj peev xwm los thaiv cov dawb receptors rau ntawm qhov chaw ntawm lub qog hlwb, cov tshuaj cheeb qhov uas cov stimulation ntawm cov tshuaj hormones neoplasm. Yog li, cov tshuaj zoo nkaus li antiestrogenic nyhuv.

Cov tshuaj "tamoxifen" phau ntawv qhia txog raws li ib tug txhais tau tias ntawm kev xaiv rau hlav nyob rau hauv lub mammary caj pas nyob rau hauv premenopausal cov poj niam. Cov tshuaj yog tsa thiab nyob rau hauv postmenopausal cov poj niam. Txawm li cas los, thaum lub sij hawm lub sij hawm no lub medicament tsis tshua zoo dua lub inhibitors (inhibitory txiav txim) aromatase (tej enzyme).

Cov tshuaj "tamoxifen" phau ntawv xav rau prostate cancer thiab txiv neej ob lub mis, daim tawv nqaij cancer, lub mis, zes qe menyuam nyob rau hauv cov poj niam. Cov tshuaj yog tshuaj thiab poj niam ntxiv lawm tshob. Kev npaj "tamoxifen - hexane" yog ntxiv tso tawm kom pom raws li ib tug adjunct tom qab lub phais kho mob ntawm lub mis carcinoma.

Lub medicament kuj yuav siv tau raws li ib tug prophylactic. Yog li, cov tshuaj "tamoxifen" muaj peev xwm ntawm thaiv cov hlab cov tshuaj no receptor thiab ob lub mis mob cancer nyob rau hauv kev noj qab nyob hlwb. Qhov no tso cai rau koj mus muab cov tshuaj rau cov neeg mob nrog ib tug high school cov predisposition mus rau mob cancer, tab sis tsis raug kev txom nyem los ntawm lawv ua ntej.

Raws li ib tug txoj cai, lub caij ntawm yeeb tshuaj koom haum saib xyuas "tamoxifen" - tsib lub xyoos. Nws yog tsim nyog yuav tau nco ntsoov ntawm no nyob rau hauv cov ntaub ntawv ntawm lub sij hawm ntawm cov tshuaj nyob rau hauv metastatic txoj kev loj hlob ntawm cancer, nws yog coj raws li ntau li ntau nws cov nyhuv kav.

Cov tshuaj txhais tau tias "tamoxifen" phau ntawv xav teem ib lub zuj zus. Feem ntau kws kho rau nees nkaum rau plaub caug milligrams ib hnub twg.

Cov tshuaj "tamoxifen" qhia tsis pub kom tau txais thaum lub sij hawm cev xeeb tub.

Cov kev siv ntawm cov tshuaj yuav ua rau ib tug xov tooj ntawm undesirable txim. Nyob rau hauv kev, cov txhais tau tias ntawm yuav ua kev nyuaj siab, kiv taub hau, pom tau qhov sib cuam tshuam, kev o ntawm lub veins. Nyob rau hauv tej rooj plaub, tej zaum yuav muaj ib tug mob taub hau, haemorrhage (paum), qhov chaw mos khaus khaus, ua pob liab vog. Feem ntau sab los muaj xws li xeev siab, kub taub hau, mob nyob rau hauv lub txhab thiab pob txha.

Nws yuav tsum tau muab sau tseg hais tias lub sij hawm lub hauj lwm zoo ntawm cov tshuaj "tamoxifen" tsis muaj zog txog. Raws li ib tug tshwm sim, cov tshuaj yog tsis muaj peev xwm pheev cawv rau cov qub hlwb. Nyob rau hauv tej rooj plaub, nws cov nyhuv yog ntxeev. Nyob rau hauv lwm yam lus, cov tshuaj pib ua zoo li cov tshuaj no thiab tsim kho lub kev loj hlob ntawm lub hlwb, es tsis txhob ntawm suppressing lawv. Yuav kom ib tug loj raws li no cov nyhuv yog txuam nrog rau cov muaj peev xwm ntawm cov tshuaj no receptor hloov nws loj, ceev, zoo los yog muaj nuj nqi. Tsis tas li ntawd, nyob rau hauv lub mis mob cancer yuav tsum tau nrog los ntawm cov xub ntiag ntawm ob qho tib si tsis zoo lawm thiab hormone-zoo hlwb. Nyob rau hauv cov ntaub ntawv no, cov tshuaj "tamoxifen" nyob rau hauv kev sib raug zoo mus rau ib tug tib cell yog zoo, thiab nyob rau hauv kev sib raug zoo rau lwm tus neeg - tsis muaj. Yog li, ib txhia receptors teb, thaum lwm tus neeg yog resistant mus rau yeeb tshuaj.

Yog hais tias post-menopausal neeg mob noj tshuaj, thiab tom qab ob los yog peb lub xyoos, nws yuav tawg paj txi txiv, tus kws kho mob feem ntau yuav siv sij hawm ib tug poj niam nyob rau aromatase inhibitors.

Nws yuav tsum tau muab sau tseg hais tias ib tug daim ntawv ntawm txoj kev kho (xws li, cov tshuaj hormones) yuav tsis hloov lwm yam kev kho mob. Nws yog tsim nyog los ua tim nyob rau hauv lub siab hais tias feem ntau cov nqi ntawm txhua hom ntawm kev txiav txim yog ua heev enhanced thaum kev daim ntawv thov.

Thoob plaws hauv kev kho mob nrog rau kev siv cov tshuaj "Tkamoksifen" yuav tsum systematically saib xyuas cov ntshav duab.