Ua pa syncytial virus: ua, cov tsos mob, kev kho mob, txim

Ua pa syncytial virus yog ib feem ntawm ib pab pawg neeg ntawm acutely tshwm sim kab mob rau ib tug ncaj loj tus naj npawb ntawm cov pejxeem feem ntau cov tub ntxhais uas muaj hnub nyoog. Xyoo-xyoos muab qhov yooj yim qhov chaw ntawm cov kab mob. Yog hais tias cov laus tus kab mob no yog dag, tus me nyuam mos muaj peev xwm tsim teeb meem loj teeb meem.

txhais

Qhov no yog ib tug kab mob uas ua rau ua pa zig. Intrigue yog hais tias nws yog ib qhov nyuaj rau kev tshawb nrhiav vim hais tias nws yog ib qho yooj yim yuav tsum tau meej pem nrog tus mob khaub thuas. Tam sim no tsis muaj tshuaj txhaj tiv thaiv tau tsis tau tau tsim, thiaj li muaj tus kab mob no tej zaum kuj tuag taus. Nyob rau hauv pw tsev kho mob txhais los ntawm cov tsos ntawm cov bronchitis, mob hawb pob thiab whistles.

etiology

Ua pa syncytial virus yog feeb meej nyob rau hauv lub cytoplasm, tom qab ripening pib budding rau hauv daim nyias nyias. Nws belongs rau tsev neeg Paramyxoviridae thiab yog tib tus neeg sawv cev ntawm no pab pawg neeg, uas yuav ua rau muaj mob loj. Txawm tias ntau yam hnub muaj ib co antigenic heterogeneity, variations txog feem ntau yog ib tug ntawm ob peb glycoproteins, tab sis epidemiological thiab soj ntsuam tseem ceeb ntawm cov kev txawv no yog tsis meej. Kab mob loj hlob nyob rau hauv ib tug xov tooj ntawm tes haiv neeg, ua rau cov tsim ntawm raug syncytia.

yog vim li cas

Ua pa syncytial virus yog ib tug neeg ailments, uas yog kis los ntawm plav mob. Lawv yog cov tau mus kis ob neeg mob thiab xov xwm. Yam ntxwv yog collective thiab tsev neeg kab mob thiab tus neeg mob ntawm nosocomial kab mob raug kaw, feem ntau nyob rau hauv xyuas cov tsev kho mob. Cov kis yog ib qho thiab feem ntau nyob ib ncig ntawm lub moos nyob rau hauv lub caij ntuj no thiab caij nplooj ntoos hlav. Qhov loj tshaj nyhav cai nyob rau hauv cov me nyuam los ntawm 4-5 lub hlis mus rau 3 xyoos. Nyob hauv ib lub hnub nyoog feem ntau ntawm cov me nyuam yog tus kab mob no, raws li tau cai nraum kev tiv thaiv, feem ntau pom dua tus neeg mob ntawm tus kab mob, tsuas yog nyob rau hauv ib tug ntau obliterated. Txawm li cas los, tom qab tag nrho disappearance ntawm tus kab mob ntawm cov tshuaj (IgA), ua pa syncytial virus yuav rov tshwm sim.

Nws kis tau los ntawm ze tus kab mob no cov neeg. . Nws tau raug analyzed thiab pom hais tias yog ib tug neeg mob txham, cov kab mob yuav kis tau yooj yim rau 1.8 m no pab pawg neeg ntawm pathogens yuav ciaj sia nyob rau ob txhais tes thiab 30 feeb, thiab nyob rau hauv cov kev kawm - rau ob peb teev.

Pathogenesis ntawm kab mob yog heev uas zoo sib xws rau kab mob khaub thuas thiab parainfluenza txoj kev loj hlob mechanism, raws li nrog rau lub zog ntawm tus kab mob mus rau lub epithelium ntawm lub pa ib ntsuj av. Nws ua hauj lwm pab kom penetrate lub pa ib ntsuj av tau, thiab cov thawj pib tu tub tu kiv hauv lub cytoplasm ntawm lub nasopharynx thiab ces ncua mus rau bronchi. Thaum no tus taw tes, muaj yog hyperplasia ntawm lub cuam tshuam hlwb thiab symplasts. Cov phenomena yog nrog constriction ntawm lub hlab ntsws thiab hypersecretion uas tom qab ua rau lawv txhaws ntawm tuab hnoos qeev. Ces txoj kev loj hlob ntawm kab mob yog txiav txim los ntawm cov neeg kawm ntawv ntawm mas muaj thiab ua pa tsis ua hauj lwm.

cov tsos mob

Ua pa syncytial kab mob no, uas microbiology yog complex thiab yooj yim rau kev tshawb nrhiav, tus kab mob no yog thaum ntxov caij nplooj ntoos hlav thiab lub caij ntuj no.

Rau hnub tim tsis qhia vim li cas muaj feem xyuam rau lub sab ua pa ib ntsuj av tau nyob rau hauv cov me nyuam thiab cov laus nyob rau sab saum toj.

Nyob rau hauv cov me nyuam, tus kab mob yuav pib nrog kub taub hau, mob loj heev mob caj pas thiab los ntswg qhov ntswg. Tsis ntev txuas nrog thiab lwm yam kev mob uas resemble mob hawb pob. Cov kab mob yog tsiag ntawv los ntawm cov nram qab no nta:

- ua tsis taus pa (ntau tshaj 40 pa ib feeb);
- xiavlus daim tawv nqaij xim (cyanosis);
- ntse thiab nquag hnoos;
- kub;
- ragged thiab sis tsis ncaj ua tsis taus pa;
- croupous foob;
- shrill pa thiab hawb pob;
- hindered exhalations.

Lower pa zig tshwm sim thaum lub hlab ntsws o. Yog hais tias nyob rau ntawm no point tus neeg mob muaj teeb meem nrog cov mov ntawm oxygen, nco ntsoov sab laj ib tug kws kho mob rau tam sim ntawd kev pab kho mob. Cov ailments tshwm sim feem ntau nyob rau hauv cov me nyuam nyob rau hauv ib lub xyoo, thiab lawv yog sai ntsuas.

kev faib

Muaj ib tug xov tooj ntawm lwm yam, uas yuav tsiag ntawv los ntawm kev ua pa syncytial kab mob no, uas yog:

- raug - tsim rhinitis, laryngitis, mob ntsws, nasopharyngitis, bronhilit, bronchitis, segmental pulmonary edema thiab otitis xov xwm;
- atypical - qhov muag plooj los yog asymptomatic kab mob.

Muaj 3 loj ntaub ntawv ntawm tus kab mob.

1. Ib qho yooj yim, tshwm sim feem ntau nyob rau hauv cov neeg laus thiab lub tsev kawm ntawv uas muaj hnub nyoog cov me nyuam. Manifests raws li me ntsis nasopharyngitis, ua pa tsis ua hauj lwm yog tsis cai. Feem ntau cov feem ntau, lub cev kub tseem zoo li qub lossis nce me ntsis, tab sis ib tug ob peb degrees. Tej yam tshwm sim ntawm intoxication yog tsis tuaj kiag li.

2. Ntsis mus rau mob hnyav, nws yog tau mus soj ntsuam cov tsos mob ntawm mob ntsws los yog bronchiolitis nrog obstructive syndrome thiab ua pa tsis ua hauj lwm. Tus neeg mob yog tam sim no, qhov ncauj cyanosis thiab ua tsis taus pa. Yog hais tias cov neeg muaj mob tus me nyuam, tej zaum nws yuav tau ib yam nkaus nyob tsis tswm, tsaug zog kus, agitated los yog lethargic. Feem ntau pom muaj ib tug me ntsis nce nyob rau hauv lub siab los yog po. Qhov kub yog feem ntau tsa, tab sis nws tshwm sim thiab yog dab tsi. Muaj yog ib tug mob loj tsawv intoxication.

3. Heavy, nyob rau ntawm no caij tsim bronchiolitis thiab obstructive ntsws. Muaj yog ib tug muaj zog tsis muaj cua nyob rau hauv uas tsuas pab ib tug oxygen daim npog qhov ncauj ua pa. Nrov traceable whistles thiab tam sim no ib tug qhia toxicity thiab ib tug muaj zog nce nyob rau hauv daim siab thiab tus po.

Los ntawm cov kev ntawm lub ntiajteb txawj nqus feem ntau muaj xws li cov nram qab no cov yam ntxwv:

- nyob rau ntawm lub zos cov kev hloov;
- teeb meem ntawm kev ua pa tsis ua hauj lwm.

Los ntawm qhov xwm ntawm tus khiav:

- tus - tsis muaj kab mob mob;
- tsis du - lub tsos ntawm mob ntsws, sinusitis thiab otitis purulent.

zaj dabneeg

Ua pa syncytial kab mob no, uas nws cov tsos mob yuav tsis meej pem nrog lwm yam kab mob tau teev rau hauv 1956 los ntawm Dr. Morris. Nws twb saib cov chimpanzees, uas tau pom rhinitis, tau pom ib tug tshiab kab mob thiab hu ua nws ib tug PAS - Chimpanzeecoriraagent (lub causative tus neeg saib xyuas ntawm tus mob khaub thuas chimpanzees). Thaum lub sij hawm ntawm kev soj ntsuam ntawm tus neeg mob cov neeg ua haujlwm uas muab kev kho mob ntawm ib tug liab, nws muaj cai nce nyob rau hauv cov tshuaj yog heev uas zoo sib xws rau tus kab mob no.

Nyob rau hauv 1957, R. Chenok faib tib yam yav nyob rau hauv kab mob cov me nyuam thiab txiav txim hais tias nws yog nws leej twg yog lub luag hauj lwm rau lub excitation ntawm ntsws thiab mob ntsws muaj dej. Tom qab ntawd thiab kom txog thaum uas tam sim no zaum unsuccessfully sim los tsim ib tug tshuaj tiv thaiv.

diagnostics

Cov kev soj ntsuam cov lus txhais ntawm tus kab mob no qhov teeb meem, vim hais tias ntawm kev zoo sib thooj nrog lwm yam kab mob. Nyob rau hauv cov laus, feem ntau yeej los ntawm cov tsos mob ntawm ntsws thiab mob ntsws muaj dej. Nyob rau hauv laboratory kev tshawb fawb uas siv cov serological txoj kev uas ntes antibody titer. Yog hais tias tsim nyog, tus kws kho mob assigns ib lub X-rays thiab kuaj ntsuam xyuas, piv txwv li, virological xeem nasopharyngeal swabs.

txoj kev kho

Cov neeg mob uas tau raug tshuaj lawm nrog ua pa syncytial kab mob no, kev kho mob yog muab nyob rau hauv ib tug complex, nyob rau hauv thiaj li yuav ntxiv dag zog rau lub cev. Txaj so yog pom zoo rau tag nrho lub sij hawm ntawm exacerbation. Pw tsev kho mob yog qhia rau cov me nyuam uas muaj teebmeem kab mob, cov me nyuam kawm muaj hnub nyoog thiab nrog ib tug nruab nrab ceeb thawj ntawm cov neeg uas twb mob. Yuav tsum muaj hnub nyoog tsim nyog noj cov zaub mov. Nws yuav tsum muaj xws li ib tug mechanically thiab sib maj zaub mov, ua kom tiav ib tug ntau yam ntawm ib txoj lw ntsiab thiab vitamins.

Tsis tas li ntawd ua causal kev kho mob, uas yog tsiag ntawv los ntawm kev siv ntawm cov tshuaj xws li leukocyte tib neeg interferon, "Anaferon", "Grippferon" thiab "Viferon". Rau hauv loj heev cov ntaub ntawv, nws yog pom zoo kom coj "immunoglobulin" thiab "Ribavirin", nws cov nqi nws txawv ntawm 240-640 rubles, nyob ntawm seb ntau npaum. Zoo kawg nkaus yuav pab tiv thaiv cov tsos ntawm cov teebmeem ntawm ntsws tshuaj "Sinagis". Yog hais tias kev kuaj kab mob mob, nws qhia tau hais tias antimicrobial txoj kev kho.

Bronchial rhuav txhua yog zoo muab tshem tawm symptomatic thiab pathogenetic kev kho mob. Nyob rau hauv cov ntaub ntawv no, siv ib tug oxygen daim npog qhov ncauj rau cov ua tsis taus pa, nws yuav ua rau nws yooj yim dua mus rau mob hnyav tsos mob thiab simplifies tus cua txaus.

Dispensary soj yuav tsum tau teeb meem. Tom qab mob ntsws pom zoo kev ntsuam xyuas tom qab 1, 3, 6 thiab 12 hlis mus ua kom tiav rov qab. Tiv Thaiv diagnostics yog tsim nyog tom qab recurrent ntsws thiab tsa tom qab hloov. Yog hais tias tsim nyog, nws yog xyuas los ntawm kev noj kev haus allergist los yog pulmonologist, thiab ua laboratory kev ntsuam xyuas.

kev kho mob ntawm cov me nyuam

Cov me nyuam yeej ib txwm muaj mob yooj yim dua, thiab lub txim yog ntau npaum li cas loj tshaj rau cov neeg laus, yog li kev kho mob yuav tsum tau txhij txhua thiab kev muab siab kho.

antivirals:

- "Ribavirin", tus nqi ntawm cov tshuaj, raws li yav tas los piav - yog muaj, thiaj li tsis ntaus lub hnab ris ntawm cov niam txiv;
- feem ntau kuj muab "Arbidol", "Inosine", "Tiloran" thiab "pranobex".

Syndromical txoj kev kho yuav tsum tau ua raws li tsim nyog twg rau cov kev kho mob ntawm mob ua pa tsis ua hauj lwm, ntsws thiab croup syndrome.

Basic antihomotoxic txoj kev kho:

- "mob khaub thuas-Luj", "Engystol" (siv los ntawm lub pib Circuit Court);
- "Euforbiumkompozitum C" (qhov ntswg tsuag);
- "Limfomiozot".

Nyob rau hauv tas li ntawd:

- "Viburkol" (qhov quav suppositories);
- "Echinacea kompozitum C" (ampoules);
- "Angin-Luj S";
- "Traumel C" (ntsiav tshuaj).

Tag nrho cov cuab yeej pab kom kov yeej lub zoo-pa syncytial virus nyob rau hauv cov me nyuam.

thawj kauj ruam

Nyob rau hauv thiaj li yuav sai sai defeat tus mob, koj yuav tsum kom zoo zoo teb mus rau lub tsos mob tshwm sim, yog li ntawd nws muaj peev xwm tau txais cov kev pab nyob rau hauv cov ntaub ntawv ntawm kev xav tau.

1. Nrhiav kev kho mob yog yuav tsum tau thaum ib tug me nyuam SARS cov tsos mob, namely mob qa, los ntswg qhov ntswg thiab mob hawb pob.
2. Yuav tsum tau hu ua tsheb thauj neeg mob, yog hais tias muaj yog ib tug siab kub, mob siab heev nrov nrov, ua hauj lwm ua tsis taus pa thiab muaj mob loj mob.

Yuav tsum tau nyob rau tej kws kho mob, raws li ib tug kws kho mob, thiab kis kab mob.

teeb meem

Tej yam tsis zoo nyob rau hauv cov pa ib ntsuj av tau muaj ib tug ua pa syncytial virus. Qhov yuav tshwm ntawm ib tug ntau ntawm tus kab mob, vim nws muaj peev xwm koom theem nrab kab mob muaj thiab ua cov kab mob xws li:

- sinusitis;
- otitis xov xwm;
- ntsws;
- mob ntsws;
- bronchiolitis.

kev tiv thaiv

Tag nrho cov kab mob yog yooj yim los kho vim hais tias lawv cov tsos mob no feem ntau muab zais. Ib tug ntawm cov kev ntsuas yog lub thaum ntxov ntawm cov kab mob thiab kev rho tawm ntawm cov neeg mob kom tiav lawv rov qab. Thaum lub sij hawm ib tug phaum xws kab mob nyob rau hauv particular mus rau hauv tus account tu ntsuas. Nyob rau hauv cov me nyuam pab pawg thiab cov tsev kho mob raug caw hnav khaub thuas qhov ncauj qhov ntswg rau cov neeg ua hauj. Cov me nyuam mos tas thiab systematically tsau tsis tau tshuaj ob txhais tes siv alkali daws teeb meem.

Rau thaum muaj xwm ceev kev tiv thaiv kev ntsuas nyob rau hauv lub foci ntawm kab mob muaj xws li cov kev siv ntawm cov tshuaj xws li "Anaferon", "Viferon", "Imunal" thiab ib tug ntau yam ntawm inducers ntawm endogenous interferon.

Immunoprophylaxis muaj xws li xws li "Motavizubam", "RESPIGHI" thiab "Palivizubam".

tshuaj tiv thaiv

Rau hnub tim, muaj tau tsim ib tug tivthaiv uas yuav tiv thaiv tau tus kab mob no. Creation yog heev active, thwmsim tau ua txij li thaum 1960, tom qab uas lub substance twj ywm nrog formalin thiab besieged alum. Xws li ib tug tshuaj tiv thaiv tshwm sim los ib tug qhia tau tsim ntawm ntshiab tshuaj, txawm hais tias cov kev tshwm sim hauv daim ntawv thov, tau soj ntsuam kuaj tsim ntau muaj mob loj. Nyob attenuated Cheebtsam ua cov tsos mob tsis heev qab ntxiag yog tig mus rau hauv tib tus kab mob no, tsuas yog tus tsiaj qus hom. Rau hnub tim, xav tias yuav cov kev purification ntawm cov tshuaj tiv thaiv ib tug subunit ntawm ib qho ntawm qhov chaw cov nqaijrog los yog attenuated hlwb, thiab ces sim mus hloov lawv mus rau lub txias.