Tus kab mob Streptococcus viridans: characterization ntawm lub pathogen thiab kab mob

Cov kab mob yog tag nrho cov nyob ib ncig ntawm peb thiab nyob hauv peb lub cev, raws li ib feem ntawm nws thiab lub ntiaj teb nyob rau hauv loj. Txawm li cas los, tsis yog txhua txhua ntawm lawv yog cov txaus ntshai rau peb noj qab haus huv, nyob rau hauv tsis tooj, cov neeg cov kab mob uas ua tau lub cev muaj los ntawm ntau yam tib neeg nruab nrog cev, thaum nws alien microbes thiab tiv thaiv kom txhob tshwm sim ntawm tus kab mob. Nyob rau hauv tas li ntawd, lub caij tseem ceeb ntawm kev tiv thaiv yog cov tiv thaiv kab mob, tab sis thaum nws yog weakening txawm conditionally pathogenic muaj peev xwm ua rau tus kab mob. Ib tug ntawm lawv brightest cov neeg sawv cev yog tus kab mob Streptococcus viridans, uas yuav tsum tau los sib tham.

cov ntaub ntawv

Txwv tsis pub xa mus rau raws li "mob qa zelenyaschy", qhov no yog ib qho cov neeg ntawm tus tib neeg lub qhov ncauj kab noj hniav, qhov twg nws yog ib ncig rau cov hniav thiab cov pos hniav, thiab feem ntau ua ib tug ua ntawm kev kho hniav caries. Qhov no yog vim hais tias nyob rau hauv cov qauv ntawm cov kab mob Streptococcus viridans muaj ib tug tshwj xeeb qhov chaw protein uas muaj peev xwm ntawm losis tswvyim dabtsi cov qaub ncaug thiab yog li txuas mus rau cov hniav. Ib tug sucrase nkag nrog cov zaub mov nws converts nws mus rau hauv lactic acid, corroding enamel. Nws nthuav lub npe nws tau txais vim hais tias thaum bacteriological sowing nws nyob rau hauv fertile av ntawm ib tug ntshav agar cov kab mob tsim ib ncig ntawm lawv pawg zelenyaschy cheeb tsam ntawm hemolysis. Txawm li cas los, muaj lwm yam pab pawg ntawm no hemolytic streptococci (kiag hemolyzed ib puag ncig) thiab uas tsis yog-hemolytic (haemolytic muaj enzymes). Nyob rau hauv kev sib piv nrog rau cov thawj kab mob Streptococcus pab pawg neeg viridans tsis txaus ntshai rau tib neeg lub cev thiab lawv muaj ntau virulent. Txawm li cas los, nrog cov weakening ntawm kev tiv thaiv, lawv muaj kev koom txawj thiab muaj ib tug pathogenic cov nyhuv, yuav ua opportunistic kab mob, thiab tsis yeej ib txwm ib qho yooj yim kawg.

microbiology

Tam sim no cia saib nyob rau hauv ntau yam dab tsi yog tus kab mob Streptococcus viridans. Yog hais tias peb tham txog cov kab mob los ntawm lub microbiological taw tes ntawm view, lawv yog kheej kheej los yog ovoid gram-zoo cocci, tsis txhob noob. Nws belongs rau cov pab pawg neeg ntawm facultative anaerobes thiab muaj xws li Streptococcaceae tsev neeg. Yog xav paub seb nws zoo li tus kab mob Streptococcus viridans, nws yog dab tsi, cia li saib nyob rau hauv lub teeb tshuab kuaj kab mob. Yog li ntawd koj yuav pom tias feem ntau ntawm lawv cov txheej txheem ntawm nyob rau hauv officers los yog mus rau hauv chains, tab sis nyob twj ywm nyob ruaj ruaj. Lawv yog ib tug txaus ntshai rau peb tsis muaj zog dag nyob rau hauv lub fact tias lawv muaj peev xwm kom tsim ib tug capsule uas tiv thaiv lawv los ntawm phagocytosis los ntawm tshwj xeeb ntshav, thiab tau yooj yim yuav hloov dua siab tshiab rau hauv ib qho L-zoo lawm, yog li mutating, thiab thiaj li tau ib tug ntev lub sij hawm nkaum ntawm lub Cheebtsam ntawm peb kws muaj txuj ci.

Sowing thiab virulence

Nutrient yuav tsum ntawm cov kab mob, tsis zoo li staphylococci, yog heev. Lawv loj hlob zoo xwb nyob rau hauv cov kev kawm nyob rau hauv uas qhov kev npaj ntawm tag nrho cov ntshav los yog cov ntshiab, raws li lawv tas yuav carbohydrates rau lub hwj chim tau siv. Uas yog vim li cas feem ntau ntawm bacteriological yub viridans streptococci siv ntshav agar. Nyob rau hauv lwm ib puag ncig, lawv yog cov heev ruaj khov, vim hais tias, piv txwv li, nyob rau hauv qhuav lom ntaub ntawv (cov ntshav, kua paug, hnoos qeev), lawv muaj peev xwm tswj tau lawv cov nqi rau ob peb lub hlis. Listeriosis, tua, lawv tuag, tab sis tsis sai li sai tau. Yog li, thaum rhuab mus rau ib tug kub ntawm 60 degrees Celsius lawv tuag xwb no tshwm sim nyob rau hauv ib nrab ib teev, thiab daim ntawv thov des. kev pab - nyob rau hauv 15 feeb.

Epidemiology

Lub fact tias cov ib txwm microflora ntawm tib neeg lub cev, nrog rau ntau cov kab mob, nkag mus rau thiab tus kab mob Streptococcus viridans - norm. Txawm li cas los, qhov no tsuas siv rau ib yam xov tooj ntawm nws hom, thiab Iwj nws tau los ntawm tus kab mob neeg, piv txwv li muaj ntawm streptococci los yog twb raug tus kab mob ib qho ntawm ntau yam ntaub ntawv ntawm kab mob (mob qa, kub taub hau, mob ntsws, thiab lwm yam). Cov feem ntau txaus ntshai cov neeg mob uas Upper pa ib ntsuj av tau kab mob, vim hais tias lawv emit ntau npaum li cas streptococci nyob rau hauv lub cheeb tsam. Li no, lub ntsiab txoj kev ntawm kab mob - plav, uas yog, los ntawm hais lus, txham, hnoos, hnia, thiab lwm yam.; nyob rau hauv tej rooj plaub kuj tau noj haus (kev noj haus) thiab hu rau (qias neeg ob txhais tes). Nws yog lub npe hu hais tias muaj ntau ntawm cov pab pawg neeg A streptococci yuav tsis tu ncua kom lawv cov virulence khoom nyob rau hauv kev sib cuag nrog cov khoom, uas yog rau lawv, nyob rau hauv qhov tseeb, ib tug dej siab ib puag ncig. Cov no muaj xws qe, mis nyuj, nqaij npua thiab shellfish.

teeb meem

Qhov tseem threatening kab mob tshwm sim los ntawm viridans thiab uas tsis yog-hemolytic streptococci, yog ua kab mob endocarditis. Qhov tseeb hais tias lub caij nplooj zeeg nyob rau hauv lub zos, thiab ces tus mauj kev thaum raug mob ntawm qhov ncauj mucosa (cov pos hniav, tus nplaig) txhuam hniav los yog pas dig hniav stomatitis tus kab mob Streptococcus viridans. Ncav lub plawv, lawv yuav tsum tau txuas mus rau lub qub thiab colonize lawv. Yog li npaj tus kab mob no. Nws pib, raws li ib tug txoj cai, cov tsos mob: tsis muaj zog, malaise, ua npaws. Qhov no yog vim feem ntau rau lub fact tias feem ntau nws yuav ua rau muaj mob loj tsawv los yog slabovirulentnye hom.

Clinic thiab ua tau

Yog hais tias qhov ua rau ntawm ua kab mob endocarditis no mas cov kab mob, tus kab mob no pib acutely thiab nrog febrile kub, mus txog plaub caug degrees. Nyob rau hauv cov ntaub ntawv no muaj thaum uas tig mus nqaij thiab mob tej pob txha, thiab auscultation hnov lub plawv yws yws ua. Cov kev txaus ntshai ntawm tus kab mob no yog kev puas tsuaj ntawm cov endocardium, i.e. cov tsos ntawm cov deformation valve kab mob Vegetations rau lawv. Nrog lawv detachment muaj microbial embolism hlab ntsha, ua rau lub plawv thiab cwj nrag. Nyob rau hauv tas li ntawd, lub aneurysm yuav tsim loj cov hlab ntsha, lub hlwb rwj, meningitis, encephalopathy thiab lub plawv tsis ua hauj lwm.