"Nolpaza": cov lus qhia rau kev siv cov ntsiav tshuaj rau pais plab thiab duodenal ulcers

"Nolpaza" - yog hypoacid cuab tam teej tug mus rau lub anti-rwj yeeb tshuaj, mus rau ib tug pab pawg neeg, lub proton twj tso kua mis inhibitor. Lub tshuaj no yog siv rau kev tiv thaiv thiab kev kho mob ntawm pathologies ntawm lub digestive ib ntsuj av. Nyob rau hauv tshuaj "Nolpaza" analogues nyob, xws li "Panum", "Zipantola", "Kontrolok", "Peptazol", "Sanpraz", "Pantazi". Tag nrho cov ntawm lawv yog tsim los ntawm cov active tshuaj "pantoprazole", uas yog KOOB-dependent thiab kav ntev ntxim rau cov inhibition ntawm pais plab acid secretion.

Muaj pes tsawg leeg thiab rau hauv daim ntawv ntawm "Nolpaza" tshuaj

Phau Ntawv Qhia hais tias 1 gastroresistant ntsiav tshuaj tshuaj "Nolpaza 20" muaj 20 mg pantaprazola. Nyob rau hauv cov ntsiav tshuaj "Nolpaza 40" - 40 mg ntawm active tshuaj. Kuj muaj nyob rau hauv lub formulation adjuvants, xws li, thiab sorbitol.

Pharmacological kev txiav txim ntawm lub medicament "Nolpaza"

Phau Ntawv Qhia txog antiulcer tshuaj tshuaj - proton twj tso kua mis inhibitors (H + K + ATPase). Cov tshuaj muaj peev xwm mus ntev-lub sij hawm hluav ntawm pais plab acid secretion. Cov tshuaj yog active tiv thaiv Helicobacter pylori thiab Helicobacter tau lug txhim khu cov nyhuv ntawm lwm yam tshuaj.

Tom qab noj cov ntsiav tshuaj "Nolpaza" kho nyhuv yog tus luv luv thiab tseem thoob plaws hauv lub hnub. Thaum tso dej txhaj tshuaj ntawm 80 mg tshuaj antisecretory nyhuv nce mus txog ib tug ncov thaum lub sij hawm hmo ntuj teev thiab txais kev cawmdim, uas muaj txhawb rau ib tug sai txo cov tsos mob thiab kev kho neeg mob ntawm ulcers nyob rau hauv lub duodenum. Yog hais tias haus tiav haum uas yuav mus ceev ceev. Cov tshuaj muaj ib tug me me raws li tau kom penetrate lub BBB, ua ke nrog rau daim card yog nyob rau hauv niam cov kua mis. Drug metabolism tshwm sim nyob rau hauv lub siab. Lub tso tawm kom pom daim ntawv metabolites, mas nyob rau hauv cov zis, cov quav yuav yuav ntes tau nyob rau hauv me me nyiaj. Nws tsis muaj lub peev xwm mus cumulating.

Indications rau tshuaj "Nolpaza"

Instruction muaj xws li kev siv ntawm cov tshuaj nyob rau hauv:

- Gastroesophageal reflux kab mob me me;

- kev tiv thaiv thiab kev kho mob ntawm cov neeg mob uas reflux esophagitis txhua ntu;

- txoj kev kho rau cov neeg uas muaj pais plab los yog plab hnyuv peptic rwj, nrog Zollinger-Ellison syndrome thiab lwm yam mob uas muaj feem xyuam nrog hypersecretion;

- kom tiv thaiv ulcers nyob rau hauv cov neeg mob uas tau txais ntev-lub sij hawm uas tsis yog-tshuaj anti-inflammatory siv tshuaj.

"Nolpaza" Cov tshuaj tej zaum yuav muab nyob rau hauv kompleknoy kev kho mob nrog antimicrobial tshuaj tua Helicobacter pylori.

Contraindications mus rau yeeb tshuaj "Nolpaza"

Los ntawm txhais tes tsis pom zoo kom siv nyob rau hauv cov neeg mob uas npau taws me ntsis, kab mob siab thiab mob npuas paug ntawm lub siab nrog hepatic tsis ua hauj lwm loj heev.

Cov kev txwv txog kev siv "Nolpaza" tshuaj

- mob ntawm daim siab zog,

- nyob rau hauv thaum yau,

- Cev xeeb tub, lactation.

phiv

Nyob rau hauv cov hnyuv tshwm sim:

- raws plab;

- qhov ncauj qhuav,

- nce qab los noj mov,

- xeev siab,

- belching,

- ntuav,

- flatulence,

- mob plab,

- cem quav,

- nce nyob rau hauv transaminases,

- hnyuv carcinoma.

Nyob rau hauv lub paj hlwb thiab piav thoob hlo kabmob:

- mob taub hau;

- qaug zog, kiv taub hau, somnolence, insomnia;

- kev ntxhov siab vim, kev nyuaj siab, co, paresthesia;

- photophobia, qhov muag plooj tsis pom kev, tinnitus.

Nyob rau hauv lub urogenital system:

- hematuria,

- edema,

- impotence.

Nyob rau hauv daim tawv nqaij:

- alopecia

- Pob txuv,

- exfoliative dermatitis,

- Kev tsis haum tshuaj xws li pob, urticaria, pruritus, angioedema.

Lwm tus nyob rau hauv daim ntawv ntawm:

- hyperglycemia, myalgia;

- kub taub hau, eosinophilia, hyperlipoproteinemia, hypercholesterolemia.

Sis nrog lwm yam tshuaj

Nrog rau cov simultaneous daim ntawv thov ntawm cov kev npaj "Nolpaza" nrog rau lwm cov tshuaj txo cov digestibility ntawm ketoconazole thiab lwm yam tshuaj nrog pH-dependent haum.

Txoj kev ntawm qhov kev siv

Ntsiav tshuaj "Nolpaza" noj 40 mg - 1 nkag ib hnub twg, nyob rau hauv thaum sawv ntxov. Qhov siab tshaj plaws koob ntawm cov tshuaj - ob zaug.

Nyob rau hauv cov kev kho mob ntawm ulcerative txhab tshwm sim los ntawm Helicobacter pylori, ua ke siv kiag nrog clarithromycin thiab metronidazole.

overdose

Tsis piav qhia ntawm cov tsos mob. Nyob rau hauv overdose pom zoo kom nqa tawm ib tug txhawb thiab symptomatic txoj kev kho. Lim Ntshav Hauv Lub nyob rau hauv cov ntaub ntawv no yog pom tias yuav pab tsis tau.

ceev faj

Ua ntej kev kho mob yog tsim nyog los tshem tawm cov nyob ntawm phem kab mob ntawm cov hlab pas thiab lub plab. Tsis pom zoo kom siv tau nyob rau hauv cov neeg mob uas tsis yog-rwj dyspepsia etiology. Laus cov neeg mob thiab lub raum puas yog tsis pom zoo kom muab ib koob tshuaj ntau dua li 40 mg / hnub. Yog hais tias muaj loj heev hepatic puas, ntau npaum yuav tsum tau tom los tswj cov theem ntawm daim siab enzymes.