Metamizole

"Metamizole" niamntiav nws anti-inflammatory, antipyretic thiab analgesic nyhuv vim lub fact uas thaiv lub synthesis ntawm prostaglandins los ntawm arachidonic acid, cuam tshuam kev mob impulses tsub kom lub tshav kub hloov lwm lub tsev thiab tsub kom lub chaw pib ntawm kev mob rhiab heev.

Hais tias cov tshuaj yog zoo heev absorbed los ntawm tus mob huam, nyob qhov twg lub hydrolyzed thiab active metabolite tsim yuav luag ib nrab uake rau cov ntshav proteins. Tso zis rau hauv lub tshuaj nyob rau hauv cov zis, raws li nws penetrates mus rau hauv niam cov kua mis.

"Metamizole" - cov lus qhia rau kev siv

Cov tshuaj no yog qhia rau cov yuav txo tau qhov mob ntawm tej keeb kwm, seb neuralgia, mob taub hau, sciatica thiab myositis. Nws kuj txais lub khaub thuas, haus rheumatism thiab lwm yam kab mob.

Nws yog pom zoo kom coj "Metamizole" los ntawm 250 mus rau 500 mg hais lus, qhov no yuav tsum tau ua 2-3 lub sij hawm ib hnub twg. Lub hnub koob tshuaj yuav tsum tsis txhob ntau tshaj 3g, ib koob tshuaj yuav tsum tsis txhob yuav ntau dua 1 gram.

Cov me nyuam hnub nyoog 2-3 xyoo yuav txhawb kom coj mus rau 50-100 mg ntawm cov tshuaj, cov muaj hnub nyoog ntawm tsib -100-200mg, mus rau xya xyoo -200 mg thiab mus txog rau 14 xyoo -250-300mg hais tias txhais tau tias, nws yog txais nyob rau hauv raws li cov tswv yim pom zoo.

Tsis tas li ntawd, "Metamizole sodium" yuav tsum noj intravenously, intramuscularly, thiab, nyob rau tib lub sij hawm nws yog xeem txog rau peb lub sij hawm thaum lub sij hawm hnub, tab sis tsis muaj ntau tshaj 2 gram ib hnub twg, thiab rau cov me nyuam nws yog pom zoo kom noj 0.1-0.2 ml ib 10 kilogram lub cev.

Contraindications

Nws tsis pom zoo kom noj cov tshuaj no noj tshuaj nyob rau hauv lub xub ntiag ntawm bronchospasm, siab rhiab heev rau Metamizole, hematopoiesis mob, raws roj ntsha hemolytic anemia, lub raum los yog hepatic insufficiency thaum lub sij hawm cev xeeb tub thiab lactation.

Tej kev phiv

Tau txais medicament "Metamizole" tej zaum yuav ua rau tej phenomena li interstitial nephritis, oliguria, zis yuav liab, proteinuria, anuria. Tsis tas li ntawd, kev tsis haum tshuaj tej zaum yuav tshwm sim raws li conjunctivitis, urticaria, angioedema, thiab tej zaum kuj anaphylactic poob siab yuav tshwm sim, bronchospastic syndrome, Lyell syndrome. Leukopenia, txo cov ntshav siab, agranulocytosis, thrombocytopenia, infiltrates ntawm cov thawj coj qhov chaw kuj yuav muaj raws li ib sab nyhuv ntawm cov tshuaj.

Ceev faj rau coj "Metamizole sodium" yog tsim nyog nyob rau ntau raug mob, muaj cov arterial hypotension, heart attack myocardial infarction, mob alcoholism thiab pib poob siab.

Yog hais tias koj xav tau sij hawm ntev siv cov tshuaj no, nws yog tsim nyog los ua tib zoo tswj pes tsawg leeg thiab mob ntawm lub peripheral cov ntshav.

Thaum simultaneous txais tos nrog chlorpromazine yuav tsim hyperthermia. "Metamizole 'yog tsis ua ke nrog benzylpenicillin colloidal ntshav hloov thiab radiopaque tshuaj.

Lub hom phiaj ntawm cov tshuaj no nrog hormonal contraceptives, uas tsis yog-narcotic analgesics, allopurinol thiab tricyclic antidepressants tej zaum yuav ua kom kho kom zoo tshuaj lom los.

Kuj muaj "Metamizol-Sodium-Pitofenone Fenpiveriniya bromide" uas yog ib tug ua ke txhais tau tias muab spasmolytic thiab analgesic nyhuv.

Yog hais tias overdose tshwm sim xeev siab, oliguria, tu-sauv, gastralgia, ntshav siab yuav txo tau, hypothermia, dyspnea, tachycardia, tinnitus, lightheadedness, nkees nkees, mob agranulocytosis, tuag tes tuag taw ntawm lub pa nqaij, impaired nco qab, hemorrhagic syndrome.

Nyob rau hauv xws li mob, pais plab lavage yog tau siv cov kev sojntsuam tau txais saline tshuaj ntaus cev thiab yeej ib txwm txais carbon. kuj yuav nqa tawm hemodialysis, yuam diuresis, thiab nyob rau hauv lub xub ntiag ntawm tu-sauv - nyob rau hauv / diazepam xeem thiab sai heev kuj barbiturates.