"Klofranil": phau ntawv qhia, xyuas, cov duab, analogues, phiv

kev nyuaj siab kev kho mob yog ua tsis tiav yam tsis muaj kev siv ntawm antidepressants, uas muaj xws li tshuaj "Klofranil". Phau ntawv kom nws siv rau qhov kev tshem tawm ntawm ntau yam phobias, mob syndromes.

hauj lwm cov tshuaj

Lub active tshuaj tivthaiv yog clomipramine hydrochloride. Ua los ntawm cov Indian lub tuam txhab "Sun Kws Industries" nyob rau hauv daim ntawv ntawm cov kob xiav round ntsiav tshuaj nrog ib tug sheath txheej.

Ntau npaum cov nqi ntawm cov clomipramine hydrochloride 0,025 g.

mechanism ntawm Action

Tshuaj "Klofranil" cov lus qhia rau kev siv hais txog tricyclic antidepressants nrog cov qauv. Nrog nws koom tes timoanalepticheskaya tau nrog psychoactive kev ua si, anxiolytic, alpha adrenotormozyaschim thiab calming nyhuv. Cov yav tas cuab yeej yog tau vim kinship nrog H ₁ histamine receptors.

Txawv analgesic, thiab gistaminoblokiruyuschim antiserotoninovym cawv. Eliminates txawj to ntawm cov zis thaum hmo ntuj suppresses lub siab xav mus noj.

Teev anticholinergic nyhuv ntawm peripheral thiab central cim tshwm sim los muaj zog Symptoms rau holinzavisimym receptor formations.

Tshuaj "Klofranil" yog hais txog antiarrhythmic tshuaj xws li quinidine, thaiv cov hlab sodium raws. Therapeutic koob tshuaj clomipramine inhibit lub conduction ntawm lub plawv ventricles.

Antidepressant kev ua si yog vim ib qho kev nce nyob rau hauv noradrenaline theem nyob rau hauv neurons ntawm cov kev sib cuag cov ntsiab lus thiab cov ntsiab lus ntawm serotonin nyob rau hauv lub paj hlwb. Cov neurotransmitters yog sau vim lub fact tias cov daim nyias nyias ntawm presynaptic neurons weaker nqa reuptake.

Heev siv ua rau ib tug txo nyob rau hauv lub haumxeeb ua si ntawm lub serotonin receptor formations ntawm lub hom thiab beta-adrenozavisimyh nyob rau hauv lub hlwb, nws yuav pab tau normalize lub adrenergic thiab serotonergic transference, tuav qhov nqi koj tshuav ntawm rov qab systems, uas yog chim depressive cov tsos mob. Ntsiav tshuaj "Klofranil" pab kom tiv nrog psychomotor ruamqauj hom, kev nyuaj siab mus ob peb vas, txhawj xeeb lawm.

Analgesic ua si manifested thaum hloov nyob rau hauv monoamine theem ntawm lub hauv paus poob siab system.

Anxiolytic nyhuv muaj tshwm sim nrog txo excitation ntawm nuclei nyob rau hauv lub hlwb qia, uas yog tswj los ntawm receptor muaj nuj nqi beta- thiab alpha 2-adrenergic hom thiab noradrenaline Circuit Court.

Lub antidepressant ua si tau raug cai rau 7 hnub tom qab pib ntawm kev kho mob.
Nyob rau hauv clomipramine piv nrog imipramine inducing cov nyhuv yog txo, thiab thaum muab piv nrog amitriptyline, lub sedative ua si nws yog tsawg tshwm tag.

Yog vim li cas noj

Medicament "Klofranil" cov lus qhia rau kev siv yog pom zoo rau cov zoo-tau kev nyuaj siab ntau txoj kev loj hlob yus los ntawm tej yam tsos mob.

Cov tshuaj yog tshuaj rau depressive syndrome cim uas accompanies schizophrenic cov tsos mob, ntev-lub sij hawm kev mob, lub cev muaj mob thiab koj tus kheej sib txawv. Lawv kho presenile thiab ua tem toob hom dab thiab lawv ces nyob rau hauv thaum yau.

Tshuaj "Klofranil" cov lus qhia rau kev siv, uas yog muab hauv qab no tus yees duab qhia kev siv nyob rau hauv obsessive-compulsive kab mob txuam nrog phobias, ntshai ntshai ntawm periodic mob ncus nyob rau hauv Oncology, migraine, rheumatic kab mob.

Nws yuav pab nrog post-herpetic txhab ntawm lub qab haus huv nyob rau hauv lub periphery, thiab post-traumatic lub peripheral neuropathy, narcolepsy, catalepsy. Lub tshuaj no yog muab rau cov kev tiv thaiv ntawm kev mob nyob rau hauv lub taub hau thiab migraine.

Yuav ua li cas siv

Nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj neeg sawv cev "Klofranil" phau ntawv qhia kom siv thaum siv cov khoom noj los yog tom qab ib tug noj mov los txo voos rau txheej nyias nyias ntawm lub plab phab ntsa.

Rau cov kev kho siv me me tshuaj, cov kev cai no siv tau rau cov neeg nyob rau hauv cov laus thiab cov hluas.

Kev nyuaj siab, obsessive compulsive-teeb meem thiab phobias kho ntau yam ntau npaum nyob rau hauv 0,025 g ntawm 3 koob tshuaj ib hnub twg. Nyob rau hauv thawj lub lim tiam, lub hnub koob tshuaj yog nce, ib hnub twg yuav npaum li cas los ntawm 0,100 mus 0,150 g Yog hais tias tsim nyog, thov ntau siab koob tshuaj. Thaum lub xeev ntawm kev txhim kho zoo nkaus li rau txhawb kev kho mob, uas yog los ntawm 0,050 mus 0,100 g ntawm cov tshuaj.

Narcolepsy nrog bouts catalepsy tshem tawm cov ntsiav tshuaj nrog ib tug txhua txhua hnub koob tshuaj los ntawm 0,025 mus 0,075 g clomipramine. Mob mob yog kho txhua txhua hnub ntau npaum ntawm los ntawm 0,100 mus 0,150 g uas yog ua ke nrog concomitant analgesics, kawg tooj yuav tsum maj txo.

Yuav kom tshem tawm lub ceeb tawm tsam thawj siv txhua txhua hnub los ntawm 0,010 grams ntawm cov tshuaj, uas yuav tsum tau ua ke nrog benzodiazepines. Yog hais tias cov tshuaj yog zoo taus, tus nqi yog nce mus rau lub tsos ntawm zoo hloov. Ces siv lub tsheb txhob sibtsoo abolition ntawm benzodiazepine agents. Kev kho mob nrog "Klofranil" phau ntawv tswv yim mus rho xwb ib nrab ib xyoo tom qab thiab tsis tau ua ntej. Thaum lub sij hawm no lub sij hawm ntawm lub sij hawm tsim nyog los nqa tawm ib tug gradual yuav txo tau nyob rau hauv cov nyiaj them yug dosing.

Nyob rau hauv cov laus hnub nyoog txoj kev kho kho txhua txhua hnub koob tshuaj 0,010 mus ces rau 10 hnub kom tus nqi ntawm cov medicament mus rau lub zoo theem, uas yog hom twg los ntawm 0,030 mus 0,050 g no koob tshuaj siv thoob plaws txoj kev kho.

pliaj sequela

Raws li nrog rau tag nrho cov antidepressants yuav ua rau cov tshuaj "Klofranil" mob tshwm sim. Anticholinergic nyhuv manifests fuzzy nrig txog kev pom ua hauj lwm accommodative paresis, mydriasis, raising lub siab nyob rau hauv lub qhov muag, ua lub plawv dhia, qhuav qhov ncauj kab noj hniav, matted yog vim li cas, fem, cem quav, ua ib ce tuag plab nonconduction cim hindered emission ntawm cov zis, hws me me compartment.

Cov kev hloov nyob rau hauv lub paj hlwb yus muaj los ntawm koj nkees nkees, asthenic txheej txheem yuav ua tsis meej pem, ntxhov siab vim, ntxhov siab, nyob tsis tswm, manic los yog hypomanic hloov. Tsis tas li ntawd, sab los yog yus muaj los ntawm aggression, nco xyaum, depersonalization, cov neeg pluag xim, insomnia, npau suav phem, asthenia.

Phiv tshua plawv thiab cov hlab ntsha yog manifested los ntawm raising los yog qhov ntswg mob atherosclerosis hloov, cev qhuav dej ces orthostatic hom conduction tsis ua hauj lwm nyob rau hauv ventricular siab variability.

Txhais tau hais tias "Klofranil" qhia rau kev siv piav qhia txog cov kev hloov nyob rau hauv lub digestive system, uas yog qhia nyob rau hauv ib tug sickening mob kab mob siab daj ntseg, kub siab, mob nyob rau hauv lub plab cheeb tsam, nce los yog poob siab noj, stomatitis, kho hniav teeb meem, ib tug kev hloov nyob rau hauv lub saj nyiam, cov blackening ntawm tus nplaig.

Hormonal mob yus muaj los ntawm edema testicular txoj kev loj hlob ntawm thoracic qog nyob rau hauv cov txivneej thiab cov pojniam ib qho kev nce, ntev ntau npaum ntawm prolactin, galactorrhea, siab los qis kev sib deev siab, deterioration potency, hyper- los yog hypoglycemia, hyponatremia, tsis tsim nyog tso tawm ntawm antidiuretic lawm.

Hloov cov chaw ua hauj lwm txoj kev ua kabmob uas txuam nrog rau yuav txo tau ntawm leukocyte thiab platelet ntshav, purpura, nce tus xov tooj ntawm eosinophils.

Cov kev tsis haum cov tshuaj tiv thaiv yuav tshwm sim nyob rau hauv daim ntawv ntawm daim tawv nqaij ua pob ua xyua nrog khaus, ntshai ultraviolet, angioneurotic edema.

Sab los txuam nrog cov thawj ntawm cov plaub hau ntawm lub taub hau, petechiae, puas kub los yog txias lub xeev, ncua los yog nquag tso zis, nrog ib tug yuav txo tau nyob rau hauv cov ntshav concentration ntawm cov proteins nrog febrile syndrome thiab kub.

Raws li ib tug tshwm sim ntawm cov cia li tshem tawm ntawm cov tshuaj yuav ua rau xeev siab, ntuav, plab mob, mob, mob taub hau, tsis xis nyob, insomnia, kev npau suav. Ib tug gradual yuav txo tau nyob rau hauv koob tshuaj cov tshuaj yuav ua rau ib tug neeg chim siab thiab ua ib lub xeev ntawm lub cev muaj zog nyob tsis tswm.

cov me nyuam

Obsessive-compulsive syndrome cim yog kho nyob rau hauv thawj zaug dosing ntawm 0,0125 rau 14 hnub siv ib gradual nce nyob rau hauv concentration, xav tias lub tsiv ntawm lub medicament. Cov koob tshuaj txhua txhua hnub tshaj 2 lub lis piam 0,100 g sib npaug los yog xam los ntawm tus luj ntawm tus me nyuam, qhov chaw uas rau txhua tus 1 kg ntawm qhov ceeb thawj tso nyiaj rau 0,003 g ntawm active tshuaj. Tom qab 14 hnub raws li los ntawm ib tug gradual nce nyob rau hauv cov tshuaj concentration rau 0,200 g los yog ua recalculation by luj.

Lub sij hawm teem tseg txhais tau tias "Klofranil" cov me nyuam yuav tsum tau txais zoo tswv yim xwm ntawm cov kev kho mob ntawm nocturnal enuresis. Initial kev kho mob yog muab ib tug txhua txhua hnub koob tshuaj nyob rau hauv ib tug npaum li ntawm 0,020-0,030 g rau lub hnub nyoog ntawm 5 txog 8 xyoo, rau cov hluas los ntawm 9 mus rau 12 xyoo yog siv 0,025-0,050 g; tom qab 12 xyoo: 0.025-0.075 g

Ua ntau npaum nqa neeg mob uas tsis pab kho tom qab 7 hnub ntawm txoj kev kho. Tag nrho txhua txhua hnub koob tshuaj tshuaj rau haus ib zaug xwb daim ntawv thov nyob rau hauv rau yav tsaus ntuj tom qab noj mov. Thaum tsis tso zis thaum hmo ntuj thaum lub sij hawm pw tsaug zog, ib nrab ntawm cov tshuaj tua tau haus dej haus mus txog 17 teev. Thaum tiav lub Desired nyhuv ntawm cov tshuaj tsis muab rau lwm 90 hnub, thaum lub sij hawm uas nqa tawm ib gradual yuav txo tau nyob rau hauv cov tshuaj ntau.

Tshuaj "Klofranil" counterparts

Muaj ntau cov tshuaj nyob rau hauv lub hauv paus ntawm clomipramine hydrochloride, pom tau hais tias interchangeable.

Ib tug xws li lub cuab tam yog lub Italian tshuaj "Anafranil", uas yog ua los ntawm "Novartis Pharma". Nws kuj muaj xws li antidepressants tricyclic series. Raws li psychotropic tshuaj kho depressive dab thiab puas siab puas ntsws. Npaj "Klofranil" thiab "Anafranil" nyob rau hauv cov qauv muaj clomipramine muaj yeeb yam li cov hydrochloride ntsev.

Ua medicament nyob rau hauv daim ntawv ntawm cov pa ntsiav tshuaj thiab pab tso tawm. Tej yam yooj yim nws ntau npaum yog 0,025 g, thiab 0,075 g retard muaj lub active ingredient. Pa ntsiav tshuaj yog lub teeb daj qab zib coated. Heev tshuaj rau daim ntawv foos liab txheej.

Muaj yog ib tug kua hom tshuaj, uas yog sawv cev los ntawm ib tug tov tso dej raws leeg thawj coj vnurtimyshechnogo thiab 2 ml. Ntau npaum "Anafranil" txhaj npaj 0,025 g ntawm clomipramine hydrochloride, uas yog yaj nyob rau hauv muaj menyuam tsis taus dej thiab glycerin.

Lwm xws yog ib tug yeeb tshuaj "Clomipramine", uas yog muaj nyob rau hauv cov ntsiav tshuaj daim ntawv rau qhov ncauj thawj coj. Rau kev tiv thaiv, lawv coated lub digestive system mucosa. Cov tshuaj yog 0,025 g clomipramine hydrochloride. embossed "25" rau xa mus rau nws nyob rau hauv txhua ntsiav tshuaj. Nyhuv ntawm cov tshuaj yog aimed ntawm combating kev nyuaj siab. Nyob rau hauv cov tshuaj prevails psychostimulants, timolepticheskoe thiab sedative kev ua si. Cov yav tas muaj nuj nqi yog txuam nrog rau cov rov qab thaiv cov hlab neuronal uptake ntawm serotonin molecules uas txhim kho neeg mob mus ob peb vas.

Nws yog siv rau cov kev kho mob ntawm depressive dab, uas yog tshwm sim los ntawm ntau yam yog vim li cas. Cov tshuaj zoo kho psihopatiiyu, schizophrenia, phobias, ceeb tsis meej, obsessive compulsive-cim, cataplexy, narcolepsy. Cov me nyuam 5 xyoo tom qab nws tau raug tsa los mus tshem tawm hmo ntuj incontinence.

Nyob rau hauv lub tshuaj "Klofranil" analogues tej zaum yuav muaj cov active ingredient lwm tshaj clomipramine hydrochloride. Piv txwv li, cov tshuaj "SONEX" nyob rau hauv nws cov nyob tus yeees yog lub active ingredient zopiclone, uas yog muaj nyob rau hauv ib koob tshuaj medicament yog 0,0075 pib pw tsaug zog, uas qhia ib tug calming, anticonvulsant thiab nqaij relaxant los. Lub zuag qhia tag nrho ntawm cov khoom "Klofranil" thiab "SONEX" yog lawv sedative zog.

Qhov Belarusian kws lub tuam txhab "Rubicon" nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj ntawm round, lenticular, nrog ib tug dawb sheath npog thiab yuav raug rau faib nyob rau hauv ib nrab. Nws yog siv los kho yam mob loj heev pw tsaug zog mob nyob rau hauv ib tug situational thiab ib ntus insomnia.

"Truksal" tshuaj

Nws yog ntseeg hais cov zoo li raws li nyob rau hauv lub analog chlorprothixene hydrochloride uas yog tioksantenoviy derivative. Nws yog ua los ntawm cov Danish lub tuam txhab JSC "Lundbeck". Kev npaj koom neuroleptic agents, uas muaj antipsychotic, sedative thiab me me antidepressant kev ua si.

Muaj plaub txawv noj tshuaj npaum cas ntawm cov tshuaj: 0,005, 0,015, 0,025 thiab 0,050 grams. Thawj peb koob tshuaj muaj nyob rau hauv daim ntawv ntawm cov xim av tableted chav nyob thiab biconvex hloov puab nrog ib tug sheath txheej. Qhov siab tshaj plaws koob sawv cev ib lub voj qe ntsiav tshuaj nrog biconvex chaw.

Antipsychotic kev ua si yog nqa tawm los ntawm inhibiting dopamine receptor formations. Thaum lub blockade ntawm cov chaw no yog antiemetic thiab analgesic nyhuv ntawm cov tshuaj. Drug cheeb qhov uas cov 5-HT2 receptor lub koom haum, α1-adrenergic thiab H1-receptors gistaminozavisimye uas ua rau adrenoblokiruyuschee, antihistaminic kev ua si.

Lub medicament yog ranked raws li neuroleptic tshuaj calming cawv, uas yog npaj los kho psychotic, schizophrenic thiab vwm tawm tsam.

Nws yog siv los mus tshem tawm thaum yau hloov tus cwj pwm, lub aim kom kov yeej lub hangover ntsoos ntsoos syndrome thaum haus cawv thiab kev siv yeeb, rau tshwj kom txhob hyperactivity, chim siab cov txheej txheem, tsis meej pem rau cov laus uas muaj hnub nyoog.

Cov tshuaj no yuav siv tau nyob rau hauv depressive hloov Besson nevroznom lub xeev.

Ua ke nrog analgesic tshuaj tshuaj "Truksal" eliminates tus kab mob dab.

Piv cuab yeej "Klofranil" nrog counterparts

Rau qhov nyob rau hauv muaj pes tsawg leeg thiab kev txiav txim ntawm lub medicament yog "Anafranil" nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj nrog zoo tib yam tso tawm. Ntau npaum ntaub ntawv retard ib tug ntau npaum ntawm 0,075 grams thiab ib tug tov rau intramuscular thiab tso dej siv yuav piv tsis tau nrog cov Indian antidepressant, vim nws yog tsis muaj nyob rau hauv daim ntawv no.

Muaj ntau cov neeg mob quaj los kuamuag vim cov nqe lus nug: Yuav ua li cas puas "Klofranil" los ntawm "Anafranil"? Ua ntej ntawm tag nrho cov, muaj ib tug txawv nyob rau hauv nyob tus yeees ntawm tsaug zog cov khoom xyaw. Cov muaj nyob rau hauv lub Indian npaj ci ntsa iab xiav, sodium carboxymethyl starch, hypromellose 2910, macrogol 6000, yog tsis nyob rau hauv lub Italian tshuaj, hais txog qhov sib txawv ntawm ob tus phooj ywg. Cov khoom xyaw rau hauv cov ntsiav tshuaj "Anafranil" hloov los ntawm stearic acid, glycerol 85%, hydroxypropylmethyl cellulose, copolymer ntawm vinylpyrrolidone thiab yas acetate, crystalline sucrose, polyvinylpyrrolidone K30, daj hlau oxide 5%, titanium dioxide, macrogol 8000.

Lub xub ntiag ntawm ob tshuaj mis nyuj qab zib tej lub bioavailability ntawm lub active tshuaj. Txawm li cas los, lub xub ntiag ntawm lactose ua rau lawv unsuitable rau cov neeg uas intolerance rau qhov no kev tivthaiv.

Lwm yam kev pab cov khoom xyaw ntawm ob analogues hloov allergic kev quab yuam, xuas, tej yam thiab clomipramine hydrochloride feem ntawm lub cev. Lawv yog cov tseem lub luag hauj lwm rau txoj kev loj hlob ntawm tag nrho cov tau tshwm sim.
Tsis zoo li "Anafranil" los ntawm "Klofranila" vim tus nqi. Italian tshuaj nqi ib me ntsis ntau tshaj ib tug Indian txoj kev counterpart.

Yog hais tias peb los sib piv li cas yog muaj zog: "Truksal" los yog "Klofranil", nws yog ntseeg hais tias cov thawj cov tshuaj muaj ib tug muaj zog sedative, calming thiab inhibitory nyhuv, uas tso cai rau los mus kov yeej ntau yam psychotic mob.

Nyob rau lub mechanism ntawm cov nyhuv ntawm neuroleptics yog sib txawv heev los ntawm antidepressant tshuaj. Action tshuaj "Truksan" aimed ntawm suppressing pathological kev puas hlwb kev ua si, los txo cov kev ua hauj lwm ntawm neurotransmitter tshuaj. Nrog kev pab los ntawm cov tshuaj "Klofranil" ntxiv dag zog rau thiab tsa los ntawm lawv cov nuj nqi.

Dopamine tso tawm yog suppressed los ntawm neuroleptics thiab antidepressants kom txoj kev loj hlob tej yam uas cov tshuaj yeeb dej caw.

Views ntawm cov neeg mob

Hais txog "Klofranil 'tshuaj xyuas yuav hnov txawv. Muaj ntau cov neeg mob uas muaj nyob rau hauv ib lub xeev ntawm kev nyuaj siab, qhov no twj tau pab tau tshem ntawm tsis zoo thiab obsessive xav, muaj kev kaj siab nyob rau hauv lub neej.

Lwm tus tshuaj nyob rau hauv alcoholism loj puas hawv dependence. Tom qab ib tug thaum kawg ntawm cov tshuaj, tus neeg mob tuaj rau ib tug txaus, calm, kuas lub xeev, tawm aggression.

Nyob rau hauv kev npaj "Klofranil" qhia rau lub tswv yim muaj ob zoo thiab tsis zoo ua cim. Qhov no yog vim lub fact tias nyob rau hauv lub "Phiv tshua" Seem no muaj ib tug lossis loj daim ntawv teev cov undesirable cov teebmeem uas tej zaum yuav tshwm sim thaum lub sij hawm kev kho mob. Nyob rau hauv kev xyaum, muaj ntau cov kws kho mob tau qhia zoo tolerability ntawm no txhais tau hais tias, tseem ceeb tshaj, xaiv qhov yog koob tshuaj thiab lub sij hawm mus kho nws yog tias tsim nyog.

Zoo txhais tau hais tias "Klofranil" xyuas muaj feem xyuam rau cov manifestation ntawm nws cov hauj lwm zoo nyob rau hauv ib tug raws sijhawm, uas tau thov cov tshuaj chaw tsim tshuaj paus. Tsis tas li ntawd xav kom nws txaus nyob rau hauv cov nyiaj txiag txoj kev npaj. Tshuaj yuav siv sij hawm nyhuv tsis pub dhau ib lub lim tiam los ntawm qhov pib ntawm kev siv, uas yog tseem ceeb heev rau cov nyem ntawm mob tawm tsam ntawm tus kab mob.

Lub disadvantage yog tias cov tshuaj kho mob tsis tau tam sim ntawd tso tseg thiab yuav tsum tau ib tug gradual yuav txo tau nyob rau hauv ntau npaum.

Cov neeg mob uas ntshai teeb meem nyob rau hauv thaum ntxov ua sawv ntawm txoj kev kho xav tias muaj zog ntxhov siab vim. Qhov no paradox yog tshwj xeeb yog tshwm nyob rau hauv thawj hnub thiab ces qub tom qab ob lub lis piam.