Kev kho mob ntawm ib qho tseem ceeb tawg

Ua ntej lub sij hawm teem kev kho mob nyob rau hauv cov neeg mob uas tawg ua txhua txhua hnub saib xyuas ntawm cov ntshav siab. Qhov no yog tsim nyog nyob rau hauv thiaj li yuav tsim kom muaj ib tug profile ntawm tawg. Nyob rau hauv kev txiav txim diurnal hloov nyob rau hauv cov ntshav siab yog xaiv txaus kho mob kho.

Kev kho mob ntawm kub siab muaj xws li medicamentous neeg thiab pharmaceuticals. Tsis-pharmacological kev kho mob ntawm tus kab mob no yog feem ntau nyob rau hauv kom ib tug noj qab nyob zoo txoj kev ua neej. Ntawm kuj zoo kawg tseem ceeb yog lub normalization ntawm nocturnal pw tsaug zog, restricting qhov kev siv ntawm ntsev, ib tug tag nrho cessation ntawm kev haus luam yeeb thiab haus dej haus cawv noj, poob phaus thiab tsis tu ncua lub cev ua si.

Tshuaj kho mob ntawm kub siab muaj txoj kev saib xyuas tus kws npaj ntawm cov nram qab no pawg:

- diuretics

- beta-blockers

- angiotensin converting-enzyme inhibitors

- calcium channel blockers

Diuretics - Ib txhia ntawm cov feem ntau nrov tshuaj rau txos cov ntshav siab. Siab txo tshwm sim vim yuav txo tau nyob rau hauv lub ntim ntawm cov kua. Undesirable nyhuv ntawm lawv cov kev siv yog ib tug txo nyob rau hauv kev sib deev yam kev ua si, photosensitivity, los ntawm pancreatitis, nce tag nrho cov roj uas txhaws, nqaij tsis muaj zog, kiv taub hau, tsis qab los noj mov, hypokalaemia. Rau sparing diuretics tooj tsiag ntawv los ntawm txoj kev loj hlob ntawm hyperkalemia uas tej zaum yuav ua rau txoj kev loj hlob ntawm endocrine ntshawv siab, intrahepatic cholestasis, kev cuam tshuam ntawm cov ntshav rheology.

Beta-blockers txo cov ntshav siab los ntawm kev txo qhov mob cov zis thiab lub inhibition ntawm renin synthesis. Lawv muab zoo nrog diuretics thiab calcium antagonists. Nyob rau hauv cov kev kho mob ntawm beta-blockers yog tsim nyog los yog ua raws li cov tshuaj txhaj koob tshuaj ntawm cov tshuaj. Overdose manifests txoj kev loj hlob mob bradycardia, hypotension, mob conduction. Nyob rau hauv cov neeg mob uas concomitant bronchial rhuav txhua tej zaum yuav tsim hnyav bronchospasm. Cov kev npaj yuav tsum tsis txhob siv rau cov neeg mob uas muaj bronchial hawb pob, insulin-dependent mob ntshav qab zib mellitus, peripheral vascular kab mob. Kev kho mob ntawm ib qho tseem ceeb tawg beta-blockers pib nrog me me koob tshuaj, tswj lub plawv dhia thiab ntshav siab, nyob rau hauv lub qhaj ntawv ntawm cov teeb meem ua rau kom cov tshuaj ntawm cov tshuaj.

ACE inhibitors - hwj chim vasodilators, los ntawm cov uas ib tug ntev lub sij hawm tswj los thaiv lub pressor nyhuv ntawm lub ntsiab zoo tshaj - angiotensin. Cov tshuaj tiv thaiv rau lub neej puas bradykinin, pab tau kom cov ntshav theem ntawm vasodilatory prostaglandins, pab nrog lub plawv tsis ua hauj lwm. Phiv los ntawm cov tshuaj yog hnoos, angioedema, hyperkalemia, tawm pob, kiv taub hau, tsis qab los noj mov thiab saj ntxaug. Lub hom phiaj tseem ceeb contraindication ACE inhibitors yog ob sab sib dho raum leeg constriction, txij thaum nyob rau cov ntaub ntawv no rau cov ntshav siab nce vim kom renin ntshav uas cov tshuaj muaj tsis ntxim.

Calcium channel blockers txo lub plawv dhia, txo cov ntshav siab, tab sis muaj ib co tsis zoo zoo, xws li mob taub hau, lub ntsej muag yaug kais dej. Tam sim no, cov tshuaj no yog dua li siv rau lub kev kho mob ntawm hypertensive crises.

Kev kho mob ntawm kub siab nyob rau hauv lub degree ntawm tus kab mob. Thaum 1 degree dua siv uas tsis yog-pharmacological kev kho mob. Hypertensive plawv tus kab mob 2 degrees yuav tsum tau lub sij hawm ntawm ib lub chav kawm ntawm kev kho mob kev kho mob tshuaj. Thaum tus kab mob no yog 3 degrees tshuaj yuav tsum tsis tu ncua.

Tiv thaiv kom txhob loj hlob ntawm tej yam kab mob yog tsis yog li ntawd nyuaj, yuav ua li cas los kho nws. Kev tiv thaiv ntawm hypertensive tus kab mob yog qhov kev tshem tawm ntawm lub etiological yam ntawm tus kab mob, raws li ib tug noj qab nyob zoo txoj kev ua neej.