"Kaltsigard Retard": cov lus qhia rau kev siv, analogs thiab xyuas

"Kaltsigard Retard" (INN "Nifedipine") yog ib tug poov hlau channel blocker thiab yog yus antianginal thiab antihypertensive pharmacological kev ua si.

Cov tshuaj qhia tau hais tias high school cov hauj lwm zoo nyob rau hauv kev tswj tawg, vasospastic thiab ruaj khov angina, Raynaud lub syndrome thiab lwm yam mob cov kab mob. Nws txhais tau tias cov muaj peev xwm los txhim kho coronary ntshav txaus, tsis siab rau li myocardial conduction.

"Kaltsigard Retard": hauj lwm thiab muaj pes tsawg leeg

Cov tshuaj no muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj, coated membrane plhaub.

Lub ntsiab active ingredient nws muaj nyob rau hauv nws cov muaj pes tsawg leeg nifedipine. Nyob rau hauv tas li ntawd, lub (yees duab tau muab los saum packing) nyob rau hauv kev npaj "Kaltsigard Retard" xws li muaj koom haum pab Cheebtsam xws li:

• Tween 80;
• cov hmoov txhuv nplej;
• magnesium stearate;
• polyethylene glycol;
• MCC;
• stearic acid;
• lactose;
• sodium lauryl sulphate.

Cov ntsiav tshuaj no yog sawv hlwv ntawm 10 daim. Yog li nyob rau hauv ib lub pob tej zaum yuav muaj los ntawm 3 mus rau 10 hlwv.

Txee lub neej yog peb lub xyoos txhais tau tias. Cia nws yuav tsum tau muaj kev tiv thaiv los ntawm lub hnub thiab qhuav tej yam kev mob ntawm kub txog li 30 degrees.

indications

Ntsiav tshuaj "Kaltsigard Retard" yuav raug muab tso rau hauv daim ntawv thov:

• stenokardicheskie kev pab ntawm sib cem;
• yog hypertensive crises hom;
• nrog Raynaud lub syndrome;
• thaum cov ntshav hom tawg;
• nrog coronary artery kab mob;
• stenokardicheskie rau kev tiv thaiv ntawm tawm tsam;
• thaum lub sij hawm hypertrophic cardiomyopathy;
• nrog pulmonary tawg ;
• thaum lub sij hawm bronchial rhuav txhua ;
• yog hais tias muaj mob nyob rau hauv lub plawv.

Dosing thiab Administration

Yuav ua li cas tau "Kaltsigard Retard"? Cov lus qhia rau kev siv ceeb toom hais tias cov yuav tsum tau ntau npaum ntawm cov tshuaj yuav tsum tau xaiv tus kws kho mob ib lub zuj zus nyob rau hauv txhua rooj plaub. Nws yuav yog nyob ntawm seb lub hom thiab qhov xwm ntawm tus kab mob no tshwm sim thiab tau cov yam ntxwv ntawm tus neeg mob.

Feem ntau, kev kho mob yuav pib nrog ib tug tau txais yam tsawg kawg nkaus koob tshuaj: 10 mg 3 los yog 4 lub sij hawm ib hnub twg. Thaum nws yuav tsim nyog rau yav tom ntej nws yuav muab ntau zog los ntawm 2 lub sij hawm. Tab sis xws li ib tug kev txiav txim siab yog los ntawm tus kws kho mob nkaus xwb.

Thaum lub sij hawm tshwm sim los ntawm tej yam kab mob, xws li mob hnyav ntaub ntawv ntawm cov tawg los yog angina, variant, ib koob tshuaj rau ntawm ib lub sij hawm tej zaum yuav tau nce mus rau 30 mg, thiab cov txais tos zaus yuav nyob twj ywm unchanged.

"Kaltsigard Retard" yuav tsum tau siv rau hauv cov dej haus thaum ib tug me me npaum li cas ntawm cov dej. Tab sis muaj tej yam teeb meem uas yuav muab suav hais tias ib qho kev zam rau txoj cai no. Piv txwv li, rau nyem ntawm hypertensive ntsoog hom muab sublingual thawj coj ntawm lub npaj (qhov chaw kawm ntsiav tshuaj nyob rau hauv tus nplaig). Rau kev tshem tawm ntawm angina nres scenario yog tau los ntawm kev txhais tau tias ntawm tso dej thawj coj ntawm 5 mg txhua txhua 4-8 teev.

Nws yog ib qho tseem ceeb ua raws li thiab teem lub siab tshaj plaws txhua txhua hnub koob tshuaj medicament los mus tiv thaiv ces tsi xam pom tshua. Haus nws yog li 120 mg, thiab thaum twg muab intravenously - txog li 30 mg.

Contraindications

Muaj tej yam teeb meem thaum ib tug "Retard Kaltsigard" (20 mg) yog kiag li contraindicated rau cov kev siv. occurrences ntawm tus neeg mob yuav ntaus nqi rau nws:

• Npau taws me ntsis rau lub active ingredient thiab lwm yam ntawm cov formulation;
• mob myocardial infarction lub sij hawm (lub thawj 8 hnub);
• mob loj heev hypotension;
• cardiogenic poob siab;
• tachycardia;
• lub plawv tsis ua hauj lwm decompensation;
• mob aortic stenosis;
• cev qhuav dej.

Nyob rau hauv tas li ntawd, lub cuab tam yuav siv tsis tau rau cov kev kho mob ntawm cev xeeb tub cov poj niam. Yog hais tias nws yuav tsim nyog los kho cov tshuaj thaum lub sij hawm lactation, mis-feeding yuav tsum tau tshem tawm.

Txoj kev nyab xeeb thiab ua tau ntawm cov tshuaj tau tsis tau qhia nyob rau hauv cov me nyuam. Yog li ntawd nws yog tsim nyog los caiv los ntawm nws cov lo lus uas peb nyob rau hauv cov neeg mob nyob rau hauv 18 lub xyoos ntawm hnub nyoog.

ceev faj

"Kaltsigard Retard" nrog huab ceev faj yuav tsum tau siv nyob rau hauv cov neeg mob uas raum tsis ua haujlwm los yog yog hais tias lawv muaj mob ntshav qab zib. Rau cov neeg laus muab txo nyob rau hauv lub hnub koob tshuaj.

Thaum lub sij hawm tag nrho lub sij hawm ntawm kev kho mob yuav tsum ua kom tiav tsis pub haus dej haus cawv.

Cov tshuaj yuav ho qeeb lub psychomotor tshua, yog li nws siv yuav tsum tau mus nrog huab ceev faj rau cov neeg uas, piv txwv li, tsav tsheb ib lub tsheb.

Kawm tiav ntawm kev kho mob yuav tsum tau ua maj mam mus tsis txhob "ntsoos ntsoos".

phiv

Kev siv cov ntsiav tshuaj "Kaltsigard Retard" tej zaum yuav ua kom muaj ntau yam tshwm sim. Ib txhia ntawm lawv yog cov heev, hos lwm yam tshwm sim yuav siv sij hawm qhov chaw nyob rau hauv ib tug cov ntaub ntawv nyob rau hauv ib txhiab, los yog txawm tsawg.

1. Los ntawm cov piav thoob hlo nruab nrog cev thiab lub paj hlwb: mob taub hau, kiv taub hau. Feem ntau yeej tsis siv cov cuab yeej muaj peev xwm ntxias stunned lub xeev, cov kev hloov nyob rau hauv nrig txog kev pom kev xaav, rhiab heev mob nqua, paresthesia, lub rov tshwm sim ntawm teeb meem nrog pw tsaug zog.
2. Nyob rau hauv ib feem ntawm lub licas: tsis tshua muaj heev co los yog myalgia.
3. Cardio-leeg tshav system: tachycardia, palpitations, kais ntawm lub ntsej muag thiab daim tawv nqaij, nrog los ntawm ib tug nov ntawm nqaij tawv ntawm tshav kub, peripheral edema. Feem ntau yeej tsis muaj peev xwm tshwm sim tsos ntawm leukopenia, anemia, asystole, thrombocytopenic purpura, thrombocytopenia, hypotension, mob, zoo ib yam li stenokardicheskie.
4. Los ntawm cov hnyuv: cem quav feem ntau tshwm sim. Feem ntau yeej tsis - ntuav, xeev siab, raws plab, kub siab. Heev tsis tshua tshwm sim ntawm kev noj cov tshuaj yuav ua tau intrahepatic cholestasis los yog gingival hyperplasia.
5. Cov kev tsis haum: exanthema, urticaria, pruritus. Heev tsis tshua muaj peev xwm tshwm sim exfoliative dermatitis.
6. Los ntawm cov pa system: nyob rau hauv tsis tshua muaj heev neeg mob bronchospasm.
7. Los ntawm cov urinary system: cov theem ntawm txhua txhua hnub zis tso zis tej zaum yuav ua rau kom. Nrog ntev-lub sij hawm kev siv ntawm cov tshuaj nyob rau hauv high koob tshuaj yuav ua rau cuam tshuam ntawm lub raum muaj nuj nqi.
8. Lwm yam: thaum pib ntawm cov kev kho mob ntau heev lossis puas liab liab thiab o ntawm tus taw thiab ob txhais tes. Heev tsis tshua txhais tau tias tej zaum yuav ntxias hyperglycemia, gynecomastia, photodermatitis, hlawv ntawm qhov chaw ntawm kev txhaj tshuaj (tso dej formulation), muaj zog lub plawv dhia.

overdose

Tau siab tshaj lub siab tshaj plaws tso cai txhaj koob tshuaj yuav ua rau bradyarrhythmias bradycardia, hypotension. Loj heev zaum koom nrog conduction slowing, cev qhuav dej.

Nyob rau hauv tas li ntawd, tej yam tshwm sim ntawm intoxication zaum yuav tshwm sim tom qab tsawg kawg yog 3-4 teev nyob rau hauv daim ntawv ntawm tsis nco qab (nyob rau hauv tej rooj plaub mus txog coma), hypoxia, cardiogenic poob siab, qaug dab peg, metabolic acidosis, hyperglycemia.

Yog xav tau tshem ntawm cov saum toj no cov tsos mob yog nqa pais plab lavage, txais tos tshuab txais hluav ncaig thiab tso dej norepinephrine, calcium gluconate los yog poov hlau tshuaj dawb nyob rau hauv ib tug tov ntawm atropine.

Lub sis ntawm cov tshuaj nrog rau lwm cov tshuaj

Ua ntej siv cov tshuaj yuav tsum pre-nyeem tsis tau tsuas yog los ntawm nws cov muaj pes tsawg leeg, indications thiab contraindications rau siv. Ib qho tseem ceeb point yog nws sis raug zoo nrog tshuaj uas tej zaum yuav tau ib feem ntawm lwm yam tshuaj los yog khoom noj. Tom qab tag nrho, ib tug yuav ua rau kom cov teebmeem ntawm cov tshuaj nyob rau hauv lub cev, thaum lwm tus neeg txo nws rau tsis muaj dab tsi. Tib yam siv rau cov kev npaj "Kaltsigard Retard". Nws yuav yog txhim khu los yog thaiv qhov kev txiav txim ntawm tej yam tshuaj. Xav txog lo lus nug no nyob rau hauv daim ntawv ntawm cov nyuag abstracts:

• ranitidine thiab cimetidine kom cov ntshav ntau;
• diltiazem tau qeeb metabolism, thiab nws thiaj li ib koob tshuaj nifedipine tsim nyog los txo;
• txiv kab ntxwv qaub kua txiv (nyob rau hauv loj qhov ntau) zog bioavailability;
• diuretics, beta-blockers, nitrates, fentanyl, haus dej cawv, tricyclic antidepressants - kom lub hypotensive cov nyhuv;
• tsub kom bioavailability cephalosporins (cefixime);
• Nws tej cov nyhuv ntawm tshwm sim los ntawm vincristine (txo feem);
• txo lub raum clearance ntawm digoxin, theophylline tsub kom cov kev ua;
• incompatible nrog rifampicin (accelerates biotransformation thiab tsis pub kom tsim zoo concentration).

analogues ntawm cov nyiaj

Puas muaj tej yam uas yuav hloov "Kaltsigard Retard"? Analogs, ntawm chav kawm, tsis muaj. Tej zaum lawv yuav zoo ib yam li qhov yooj yim kev npaj ntawm cov muaj pes tsawg leeg (nyob rau hauv kev lub active tshuaj) los yog lub hom ntawm kev txiav txim rau tus kab mob. Txawm li cas los, txhais tshuaj "Kaltsigard Retard" muaj lawv tus kheej peculiarities thiab sib txawv. Piv txwv li, tej zaum nws yuav tso tawm daim ntawv no, txoj kev thiab tus xov tooj ntawm daim ntaub ntawv, lub siab tshaj plaws txhua txhua hnub koob tshuaj thiab li ntawd. Yog li ntawd ua ntej koj hloov ib cov tshuaj rau lwm tus, koj yuav tsum tau nrog ib tug kws kho mob.

Yog li ntawd, qhov zoo tshaj plaws lub npe hu tshuaj analogues "Kaltsigard Retard" yog cov nram qab no cov tshuaj:

• "Kordafleks".
• "Nifedeks".
• "Nifedipine".
• "Fenamon".
• "Cordipin".
• "Kordafen"
• "Nifelat".
• "Fenigidin".
• "Adalat".
• "Nifecard".
• "Corinfar".
• "Depin".

Xyuas ntawm kev npaj

Yuav ua li cas cov neeg mob hais txog cov tshuaj "Kaltsigard Retard"? Xyuas Muaj ob zoo thiab tsis zoo. Koj yuav tsum pib ib yam nrog rau pros.

Firstly, cov neeg mob qhia siab miv nyuas siv zug thiab ib tug ncaj dav spectrum ntawm kev txiav txim.

Ob, yuav tsis tab sis zoo siab txhais tau tias heev uas tsis muaj nqi (los ntawm 50 mus rau 300 rubles nyob rau hauv lub pob loj).

Qhov tshaj plaws xwb uas yuav raug xam tias yog ib tug tseem ceeb disadvantage - yog lub rov tshwm sim ntawm sab los nyob rau hauv daim ntawv ntawm cov mob taub hau, xeev siab thiab thiaj li nyob. Txawm tias, raws li qhia, tom qab kom txhob muaj cov koob ntawm cov tshuaj tag nrho cov saum toj no cov tsos mob sai sai zoo. Nws yog yog li ntawd tseem tau hais tias qhov ua rau ntawm lub sab los yog raws nraim qhov tsis ncaj ncees txheej txheem.