Gentamicin tshuaj pleev: kev siv ntawm lub mechanism ntawm qhov kev txiav txim thiab

Cov tshwm sim ntawm cov kev ua ntawm kab mob (Micromospora purpurea) tsim tshuaj tua kab mob - gentamicin. Nws yog siv nyob rau hauv daim ntawv ntawm cov gentamicin sulfate (Gentamicyni sulfas). Qhov no hmoov nkag soluble nyob rau hauv H2O. Aqueous lub ntsiab es resistant, mas kub. Khoom Form - 4% aqueous lub ntsiab, hmoov thiab 0.1% tshuaj pleev. Nyob rau hauv qhov kev npaj ntawm ointments siv ntxiv tshuaj (petrolatum thiab dawb ciab). Gentamicin tshuaj pleev siv rau lwm daim ntawv thov. Cov tshuaj muaj ib tug tshuaj tua kab mob (Gentamicyni sulfas), teej tug mus rau lub aminoglycoside series. Nws qhia tau hais tias ib tug ntau spectrum ntawm kev txiav txim.

Gentamicin tshuaj pleev: lub mechanism ntawm qhov kev txiav txim

Nyob rau spectrum ntawm antibacterial kev txiav txim yog txawv los ntawm lwm yam tshuaj tua kab mob ntawm no pab pawg neeg. Teev bactericidal kev ua si rau feem ntau gram-tsis zoo microorganisms thiab grampozitichnyh, xws li ntawm Proteus, Pseudomonas aeruginosa, klepsiely, Campylobacter, E. coli, Staphylococcus aureus thiab lwm tus neeg. Tsawg zoo tiv thaiv steptokokkov, Enterococci, Clostridium. Thaum ua ke lub sij hawm nrog gentamicin penicillins (oxacillin, carbenicillin, ampicillin) tsu zoo bactericidal kev ua si tiv thaiv entero- thiab streptococci. Gentamicin sulfate muaj tsis ntxim rau cov co kab mob, kab mob, protozoa thiab fungi. microbial kuj mus tshuaj tua kab mob yog ua maj. Nws yuav tsum tau hais tias tus kab mob los hais tias yog resistant rau tshuaj tua kab mob xws li kanamycin thiab neomycin, thiab muaj kuj mus gentamycin (ntoo khaub lig-kuj) nyhuv.

Txij li thaum lub tshuaj pleev muaj gentamicin tshuaj tua kab mob aminoglycoside series, nws tsis zoo penetrates ntawm daim tawv nqaij thiab qog ua kua week. Nyob rau hauv no hais txog, qhov no tshuaj pleev tsis yog qhia tau hais tias resorptive kev txiav txim. Duration ntawm kev txiav txim tom qab ib daim ntawv thov yuav tsum khaws cia rau 8-12 teev. Yog li ntawd, cov puas nto gentamicin tshuaj pleev yog thov ib zaug los yog ob zaug ib hnub twg, noj mus rau hauv tus account lub heev thiab cov hoob kawm puas lwm pathology. Lub active ingredient (tshuaj tua kab mob) tas los ntawm ob lub raum, zoo unaltered lub xeev, nyob rau hauv high txaus ntau.

Gentamicin tshuaj pleev: cov lus qhia rau kev siv

Qhov no tshuaj yog dav siv nyob rau hauv phais xyaum rau kev kho mob ntawm cov qhov txhab nyob rau hauv II theem ntawm lub qhov txhab tom qab txheej txheem nyob rau hauv thiaj li yuav tiv thaiv tau cov kev loj hlob ntawm purulent kab mob. Gentamicin tshuaj pleev yog siv rau Burns thiab frostbite. Dermatologists tshuaj pleev siv rau cov kev kho mob ntawm cov kab etiology ntawm daim tawv nqaij kab mob (ces dag folliculitis, pyoderma, dermatitis, eczema, abrasions, ulcers, pob txuv, etc.) tshwm sim los ntawm cov kab mob rhiab rau gentamicin. Gentamicin tshuaj pleev kuj yuav siv tau nyob rau hauv cov kev kho mob ntawm tsev neeg kev raug mob (me wounds, khawb).

Dosing ntawm cov tshuaj

Tom qab uas tsim nyog (adhering rau cov kev cai ntawm asepsis thiab antisepsis) kev kho mob ntawm cov qhov txhab thiab Burns gentamicin tshuaj pleev yog thov ncaj qha rau ntawm lub qhov txhab nto, ces thov ib tug gauze ntaub qhwv. Tshuaj tua kab mob tshuaj pleev kuj yog raug rau tus thawj ntaub qhwv, thiab ces mus rau qhov chaw ntawm lub qhov txhab. Feem ntau, rau kev kho mob ntawm cov qhov txhab siv tshuaj pleev ib hnub ob zaug, thiab cov kev kho mob ntawm kub - ob zaug ib lub lim tiam. Nyob ntawm seb lub hom thiab qhov ntawm tus kab mob kev kho mob yuav kav mus txog rau ob lub lim piam. Nyob rau hauv lub xub ntiag ntawm ulcers thiab erosions ntawm lub qhov txhab yog thawj kho nrog disinfectants (ntawm Hydrogen Peroxide 3%, 2% cawv tov ntawm boric acid), tom qab uas lub tshuaj pleev yog thov gentamicin. Siv cov tshuaj tej zaum yuav ntxias phiv uas yog manifested nyob rau hauv daim ntawv ntawm cov kev tsis haum tshuaj thiab yaug kais dej. Daim ntawv thov gentamicin tshuaj pleev yog ua rau lub xub ntiag ntawm kev tsis haum tshuaj mus rau lub tshuaj tua kab mob thiab qhov kuv theem ntawm lub qhov txhab kho neeg mob.