"Dekapeptil": cov lus qhia rau kev siv, muaj pes tsawg leeg, indications thiab contraindications

Yuav ua li cas mus thov cov tshuaj "Dekapeptil"? Cov lus qhia rau kev siv ntawm cov tshuaj no yuav tsum tau muab nthuav hauv qab no. Koj kuj yuav kawm txog cov indications rau kev siv ntawm cov tshuaj, nws analogs, thiab lwm yam kev phiv cov txheej xwm.

"Dekapeptil": kev piav qhia txog cov tshuaj, nws muaj pes tsawg leeg thiab daim ntawv

Saib medicament yog muag raws li ib tug ntshiab thiab tsis muaj kob txhaj tsis muaj tsis muaj tsw thiab impurities.

Lub ntsiab tivthaiv ntawm cov tshuaj no yog triptorelin acetate. Nyob rau hauv tas li ntawd, nws muaj xws li cov khoom xyaw xws li glacial acetic acid, sodium tshuaj dawb thiab dej rau txhaj tshuaj.

Yuav cov tshuaj "Dekapeptil" Diam duab uas yog nyob rau hauv no tsab xov xwm yuav ua tau nyob rau hauv koob txhaj tshuaj, vials, ua kom tiav nrog ib rab koob, uas yog nyob rau hauv fej contour hlwb thiab thawv ntawv, ntsig txog.

Qhov kev txiav txim ntawm cov tshuaj (pharmacological)

Yuav ua li cas yog cov tshuaj "Dekapeptil"? Cov lus qhia rau kev siv qhia tias ib tug hluavtaws analogue ntawm GnRH, los yog thiaj li hu ua gonadotropin-tso lawm.

Tom qab thawj coj ntawm cov tshuaj active tshuaj nws ua ib qho kev nce nyob rau hauv cov theem ntawm LH thiab FSH nyob rau hauv cov ntshav, uas nws thiaj li ua rau yus mus rau ib tug nraum nce nyob rau hauv lub concentration ntawm kev pw ua ke cov tshuaj hormones. Nruam stimulation ntawm lub pituitary (e.g., nyob tsis tu ncua daim ntawv thov kev siv yeeb tshuaj) muaj txhawb blockade gonadotropic lag luam. Cov tshwm sim ntawm zoo li no los yog ib tug txo nyob rau hauv lub xov tooj ntawm cov tshuaj hormones (sib deev) los menopausal los yog postcastration. Cov teebmeem yog reversible.

Kev tshawb fawb nyob rau hauv laboratory tsiaj kuj tsis muaj mutagenic los yog teratogenic los xam tau tias yog tshuaj.

Cov tshuaj ntawm cov tshuaj txhaj

Yuav ua li cas pharmacokinetic zog yam ntxwv ntawm "Dekapeptil" tshuaj? Cov lus qhia rau Siv hais tias nyob rau hauv thawj 50-90 feeb tom qab thawj coj ntawm cov tshuaj nyob rau hauv cov ntshav nce mus txog nws cov ncov triptorelin. Ntxiv concentration ntawm no yam khoom uas yog markedly txo (thaum lub sij hawm ib hnub).

Lub ib nrab-lub neej sij hawm ntawm lub ntsiab tivthaiv yog 18,7 feeb. Hais txog 4% ntawm triptorelin tshwm nyob rau hauv cov zis nyob rau hauv unchanged daim ntawv.

Nws yuav tsum tau muab sau tseg tias tshuaj ntawm cov tshuaj ntsuam xyuas tau ua nyob rau hauv cov neeg uas muaj ib tug paub tseeb hais tias mob ntawm uterine fibroids los yog endometriosis, raws li zoo raws li nyob rau hauv kev noj qab nyob txiv neej tuaj pab dawb thiab cov neeg mob qog ntawm lub prostate.

Indications rau kev tswj hwm ntawm ib tug injectable tshuaj

Vim li cas prescribers "Dekapeptil"? Indications rau kev siv ntawm cov tshuaj rau cov poj niam yog:

• uterine fibroids;
• ntxiv lawm tshob kho siv deev yees (e.g., embryo hloov lwm lub tsev, IVF);
• endometriosis.

Raws li rau cov txiv neej, nws yog ib lub cuab tam pom zoo rau cov symptomatic kev kho mob ntawm tshuaj-dependent advanced carcinoma ntawm lub prostate.

Bans cov kev taw qhia ntawm cov tshuaj rau cov txiv neej thiab cov poj niam

Nyob rau hauv tej rooj plaub, koj muaj peev xwm tsis nkag mus rau hauv lub tshuaj "Dekapeptil"? Cov lus qhia rau kev siv qhia tau tias cov tshuaj no yog contraindicated rau cov poj niam:

• thaum pub niam mis;
• cev xeeb tub;
• soj ntsuam kev tshwm sim thiab kev pheej hmoo ntawm txha.

Nws yuav tsum tau muab sau tseg tias cov kev ceev faj cov tshuaj siv nyob rau hauv lub tua ntawm cov kev pab cuam nyob rau hauv IVF cov neeg mob uas polycystic zes qe menyuam (i.e., yog hais tias tus naj npawb ntawm cov hauv paus, uas yog txiav txim los ntawm ultrasound, yog ntau tshaj 10).

Yuav kom muaj zog nrog txiv neej pw xam tau tias yog tshuaj yog ua rau:

• nrog phais castration (ua ntej);
• prostate carcinoma (hormone ywj siab).

General kev txwv tsis pub mus rau lub lo lus uas peb ntawm lub cuab tam yog npau taws me ntsis rau triptorelin neeg mob los yog mus rau lwm cov Cheebtsam ntawm cov tshuaj.

Cov tshuaj "Dekapeptil": cov lus qhia rau kev siv

Cov tshuaj no yog npaj rau cov subcutaneous thawj coj. Nyob rau hauv endometriosis, prostate cancer thiab uterine cancer tshuaj no yog muab nyob rau hauv ib tug npaum li ntawm 0.5 mg / ml ib zaug ib hnub twg rau ib lub lim tiam. Nyob rau lub 8 hnub dhau mus rau ib tug txij nkawm koob tshuaj ntawm 0.1 mg / ml ib zaug ib hnub twg.

Nyob rau hauv cov kev kho mob ntawm no neeg sawv cev yuav tsum tau ua ultrasound thiab saib ntau thiab tsawg fibroids thiab endometriosis foci.

Thaum lub IVF cov kev pab cuam medicament yog muab raws li kev cai (yuav ua tau luv luv los yog ultrashort). Nyob rau hauv thiaj li yuav tiv thaiv kom txhob txhaj qhov chaw tshua post-txhaj txhua lub sij hawm hloov.

Thaum siv cov tshuaj "Dekapeptil Depot"? Cov lus qhia rau Siv hais tias qhov cuab tam yog qhia thaum lub sij hawm heev kawg ntawm txoj kev kho. Nws kuj muab subcutaneously nyob rau hauv lub plab cheeb tsam, los yog intramuscularly 1 lub sij hawm nyob rau hauv 30 hnub.

Qhov npaj tov twb siv tam sim ntawd. Endometriosis thiab uterine myoma txoj kev kho pib nyob rau hauv thawj hnub ntawm lub voj voog. Qhov no kev kho mob yuav tsum kav txog 3-6 lub hlis. Thaum lub prostate kho mob cancer yog tseem nqa tawm rau ib ntev lub sij hawm.

Thaum IVF tshuaj "Dekapeptil Depot" muab ib zaug rau tej hnub ntawm lub voj voog.

Tshwm sim los ntawm-cim

Uas ua rau kev phiv tshuaj "Dekapeptil" tshuaj? Cov lus qhia, xyuas tau qhia hais tias cov kev phiv, uas nyob rau hauv lub keeb kwm yav dhau ntawm daim ntawv thov ntawm no yeeb tshuaj vim ib tug txo nyob rau hauv lub xov tooj ntawm tus txiv neej pw cov tshuaj hormones rau hauv cov ntshav, uas muaj peev xwm nws thiaj li ua rau txoj kev loj hlob ntawm cov tsos mob xws li kev nyuaj siab, mus ob peb vas lability, nquag mob taub hau, weakening ntawm libido, pw tsaug zog teeb , kub flashes, koj qhov hnyav nce, thiab muaj zog tawm hws. Nyob rau hauv tas li ntawd, cov nram qab no hloov tau cai nyob rau hauv ib co neeg mob:

• rhuav txhua ntawm cov mob txeeb zig, paresthesia, mob thaum lub sij hawm kev sib deev com;
• qhov muag plooj tsis pom kev, rov qab mob, nqaij tsis muaj zog;
• poj niam - uterine los ntshav thiab paum dryness;
• cov txiv neej - gynecomastia, txo potency thiab txo qhov loj ntawm lub noob qes;
• xeev siab, kais, tsis qab los noj mov, khaus;
• kub taub hau, hypercholesterolemia, mob pob txha tshwm sim los ntawm metastases;
• myalgia, txha caj qaum compression, anaphylaxis;
• arthralgia, mob ntawm lub qhov koob tshuaj, cov pob txha demineralization (nrog heev siv);
• Lymph node o, thrombophlebitis, o ntawm ko taw;
• tsis ntawm cov plaub hau rau ob txhais ceg, hauv siab thiab caj npab, txo hwj txwv txoj kev loj hlob.

Nws yuav tsum tau muab sau tseg tias tag nrho cov ntawm cov kev phiv ploj tam sim ntawd tom qab qhov kawg ntawm txoj kev kho.

Tshuaj kev sib tshuam, overdoses

Overdoses xam tau tias yog tshuaj muaj cai. Nrog rau txoj kev loj hlob ntawm tej tsis zoo tshwm sim nyob rau hauv lub keeb kwm yav dhau ntawm lub dhau heev lawm koob tshuaj yuav tsum tau nqa tawm symptomatic kev kho mob.

Tshuaj kev sib tshuam "Dekapeptil" tsis tau tsim muaj nrog lwm yam tshuaj mas siv.

Cov ntaub ntawv rau cov neeg mob

kev kho mob tshuaj "Dekapeptil" yuav tsum muaj nyob rau hauv nruj tswj ntawm lub theem ntawm kev sib deev cov tshuaj hormones rau hauv cov ntshav.

Cov poj niam yuav tsum nqa tawm ib txoj kev tshawb nyob rau hauv kev txiav txim kom tsis txhob muaj ib tug ua tau cev xeeb tub. Thaum lub sij hawm txoj kev siv cov tshuaj yog tsis tsim nyog rau siv hormonal contraceptives, raws li zoo raws li npaj muaj estrogens nyob rau hauv nws tus kheej.

Tus neeg mob yuav tsum tau qhia hais tias thaum lub sij hawm hauv chav kawm ntawm kev kho mob xam tau tias yog poj niam cov tshuaj yuav tsis tuaj kawm ntawv.

Kev siv cov no lub cuab tam nyob rau hauv cov txiv neej tej zaum yuav ua rau ib tug ib ntus deterioration nyob rau hauv lawv tus mob. yuav tsum tam sim ntawd pom ib tug kws kho mob thaum tshwm sim tsis zoo mob.

zoo xws li cov tshuaj

Yuav ua li cas yuav hloov tau lam tshuaj "Dekapeptil"? Analogues rau cov tshuaj no yog heev yooj yim mus nrhiav tau, li ntawd, ib tug zoo li txoj kev yuav tsum hais tsuas yog ib tug kws kho mob.

Raws li cov nqe lus ntawm ib co kws txawj, cov tshuaj yuav tsum tau muab suav hloov los ntawm cov hauv qab no txhais tau tias: 'Zoladex', 'Buserelin Depot "," Diferelin "," triptorelin. "

Xyuas ntawm txhaj tshuaj

Tam sim no, rau txoj kev kho ntawm endometriosis, deev system thiab lwm yam kab mob ntau npaum thiab zoo yog agonists ntawm gonadotropin-tso lawm. Cov no muaj xws tshuaj xws li "Dekapeptil", "Diferelin ',' Zoladex 'thiab lwm tus neeg. Txawm li cas los, nws yuav tsum tau muab sau tseg hais tias tus nqi ntawm xws nyiaj tsis pub rau lawv lug siv nyob rau hauv kev kho mob xyaum. Nyob rau hauv no hais txog, cov lus nyob rau lawv daim ntawv thov, muaj yog tsis heev npaum li cas.

Raws li cov ntaub ntawv ntawm cov kws txawj, cov tshuaj "Dekapeptil" feem ntau kws kho rau cov kev kho mob ntawm uterine fibroids (ntev 5-6 lub hlis). Tej kev siv cov medicament ua nyob rau hauv ib tug txo nyob rau hauv uterine ntim thiab qhov ntau thiab tsawg ntawm ntshav. Tom ntej no ua kev phais. Yog li, kev kho mob "Dekapeptilom" twb muab raws li ib tug preoperative npaj.

Muaj ntau cov neeg mob hais tias tom qab cov kev taw qhia ntawm cov tshuaj lawv feem ntau pom nyob rau hauv cov kev txhaj tshuaj rau ntawm qhov chaw mob, khaus thiab liab. Tsis tas li ntawd mob taub hau, kub flashes, insomnia thiab qaug zog.

Zoo ceeb toom txog qhov cuab tam feem ntau tawm cov poj niam siv "Dekapeptil" IVF raws tu qauv. Tsaug rau cov tshuaj no nyob rau hauv feem ntau qhov kev siv txoj kev ntawm lub embryo mus rau hauv lub tsev me nyuam xaus ntse. Ntawm sab los hais rau hauv lub fairer poj niam txiv kub flushes thiab tawm hws.