Cov tshuaj "Avastin": tus neeg mob testimonials, cov lus qhia rau kev siv, phiv

Cov tshuaj "Avastin" yog suav tias yog ib tug antitumor neeg sawv cev, uas yog hais txog monoclonal tshuaj. Thaum lub sij hawm daim ntawv thov ntawm cov tshuaj yog ib tug txo kev vam meej ntawm metastatic kab mob thiab microvascular permeability nyob rau hauv phem hlav ntawm ntau hom, tshwj xeeb yog cov muaj feem xyuam rau cov poj niam lub mis, nyuv, thiab pancreas thiab prostate.

cov tshuaj

Qhov tshuaj "Avastin" nyob rau hauv daim ntawv ntawm ib tug concentrate uas yog npaj los npaj cov tshuaj rau Txoj kev lis ntshav yuav tsum tsis muaj kob los yog me ntsis brownish perceptible.

Cov yooj yim tshuaj tshuaj yog bevacizumab. Lub cuab tam yog muaj nyob rau hauv pob khoom ntawm 100 mg, nrog 4 ml ntawm active tshuaj thiab 400 mg / 16 ml.

pharmacological los

"Avastin" - tiv thaiv mob tshuaj uas cheeb qhov uas cov tsim ntawm tshiab cov hlab ntsha uas muab cov pa thiab as-ham rau cov nqaij neoplasms thiab yog li tso cai hloov lwm lub tsev ntawm ib tug txhoj puab heev cancer nyob rau hauv lub mob nyob ntev. "Avastin" (cov lus teb ntawm cov neeg mob thiab cov kws kho mob - ntawv pov thawj) ua overwhelmingly nyob rau hauv lub metastasis ntawm ntau yam phem hlav.

Rau qhov cuab tam yog yus muaj los ntawm ib tug tsawg heev npaum li cas ntawm kis rau hauv lub cev, nyob rau hauv tas li ntawd, nws yog ntev txaus tshem tawm los ntawm lub cev, uas tso cai rau kom muaj qhov yuav tsum tau npaum li cas ntawm lub ntsiab tivthaiv ntawm cov tshuaj los ntawm txhaj nws nruj me ntsis raws li cov lus qhia - ib zaug nyob rau hauv 14-20 hnub. Muab lam cov khoom no yog tsis nyob rau hauv lub siab los yog raum, thiab nyob rau hauv tag nrho cov hlwb ntawm lub cev rau 18 hnub rau cov txiv neej thiab rau cov poj niam - 20.

Tab sis yog zoo "Avastin"? Testimonials hais tias qhov no yog ib tug zoo heev tshuaj, yog koj muab nws nrog cov kws khomob nyob rau hauv ntau hom mob qog nqaij hlav. Qhov no txhais tau tias muaj nuj nqis tsub kom cov ciaj sia taus lub sij hawm ntawm cov neeg mob nyob rau hauv tag nrho cov pawg, nrog rau cov kev vam meej ntawm tus kab mob no tshwm sim.

"Avastin": indications rau kev siv

Qhov no tshuaj yog dav siv nyob rau hauv kev kho mob cancer. Cov kws kho mob muab tshuaj rau nws:

1. Nyob rau hauv metastatic colorectal cancer. Cov tshuaj no yog pom zoo rau siv nyob rau hauv ua ke nrog cov kws khomob raws li 'fluoropyrimidine'.
2. Nyob rau hauv metastatic mob cancer mis. Nws yog siv raws li ib tug thawj kab ntawm kev kho mob nyob rau hauv nrog cov "paclitaxel".
3. Thaum inoperable, nrog los ntawm ib tug loj tus naj npawb ntawm metastases los yog neplosko-, uas tsis yog-me me ntawm tes ntsws mob qog nqaij hlav - raws li ib tug thawj kab txoj kev kho nyob rau hauv ua ke nrog nrog cov kws khomob platinum raws li medicinal npaj.
4. Nyob rau hauv heev los yog metastatic cancer, uas cuam tshuam raum hlwb - raws li ib tug neeg sawv cev rau thawj txoj kev kho nyob rau hauv nrog "interferon Alpha-2a".
5. Thaum glioblastoma nyob rau hauv nrog tawg txoj kev kho thiab 'temozolomide' nyob rau hauv cov neeg mob uas muaj tshiab khiv paub hais tias, nyob rau hauv monotherapy los yog nyob rau hauv nrog "irinotecan" nyob rau hauv cov neeg mob uas recurrent glioblastoma los yog cancer mob.
6. Cov neeg mob uas muaj mob "kab mob qog hlav ntawm cov poj niam qhov chaw mos mutilation", thiab nyob rau hauv thawj peritoneal cancer. Nyob rau hauv cov ntaub ntawv no nws yog pom zoo kom muab cov tshuaj "Avastin" raws li cov thawj kev kho mob kho nyob rau hauv ua ke nrog "carboplatin" thiab "paclitaxel".

Tsis tas li ntawd, ib tug yeeb tshuaj muab nrog "carboplatin" thiab "Gemcitabine" muab rau cov kab mob los yog rhiab rau platinum-raws li cov neeg ua hauj rau cov neeg mob nrog rau mob cancer ntawm tus poj niam qhov chaw mos kabmob los yog lub peritoneum, uas tsis tau raug kho los ntawm lub cuab tam, los yog lwm yam ntawm ib tug inhibitor ntawm VEGF.

Yuav ua li cas mus nkag rau "Avastin"?

"Avastin" (cov lus teb ntawm cov neeg mob thiab cov kws kho mob paub meej tias nws) - ib tug zoo tshuaj, tab sis nws yuav tsum tau kom muab, thiab tsuas yog nyob rau hauv lub saib xyuas ntawm cov kws kho mob. Nws yog nruj me ntsis txwv tsis pub mus rau hauv lub dav hlau - tsuas yog intravenously, thiab ces li maj mam li sai tau. Lub xam yog 5 mg ib 1 kg ntawm lub cev hnyav 1 lub sij hawm nyob rau hauv ob lub lis piam.

Qhov yuav tsum tau npaum li cas ntawm concentrate yog diluted nyob rau hauv 100 ml 0.9% sodium chloride. Thawj koob tshuaj yog pom zoo kom nkag mus rau ib tug thiab ib tug ib nrab xuaj moos tom qab cov kws khomob, ntxiv txhaj tshuaj ntawm "Avastin" yog ua li cas ua ntej los yog tom qab ntawm txoj kev. Yog hais tias tus thawj saib xyuas ntawm cov tshuaj tus neeg mob twb tsis muaj teeb meem, qhov ntau nws yuav muab tsis pub dhau ib teev, thiab tag nrho cov tom ntej tshuaj - rau ib nrab ib teev, tab sis yog hais tias qhov thib ob tau tau kis mob prick zoo.

Txawm koob tshuaj yog tsis pom zoo kom txo cov xub ntiag ntawm undesirable los, yog tias tsim nyog, muab ncua tseg los yog txhob muab cov kev kho mob.

Yog hais tias tus neeg mob tau raug kuaj metastatic colorectal cancer, cov pom zoo thawj zaug koob tshuaj 5 mg ib kg lub cev hnyav ib zaug txhua txhua 14 hnub los yog 7.5 mg / kg, tab sis tom qab txhua txhua 21 hnub. Yog hais tias ib tug thib ob kab txoj kev kho, cov tshuaj yog nce los ntawm 2 lub sij hawm.

Yog hais tias ib tug poj niam mob qog nqaij hlav ntawm lub mis, nyob rau hauv cov ntaub ntawv no, tus thawj txhaj yog pom zoo hais tias lub formulation ntawm 10 mg / kg thiab mus nqa tawm ib qho kev txhaj tshuaj txhua txhua ob lub lis piam. Los yog peb, tab sis nyob rau hauv cov ntaub ntawv no nws yog muab tshem mus rau 15 mg rau ib kg lub cev hnyav.

Yog hais tias muaj cov cim qhia ntawm kev vam meej ntawm tus kab mob, kev kho mob yuav tsum tau tso tseg.

Nrog ntau inoperable, recurrent, los yog metastatic neplosko- los yog uas tsis yog-me me ntawm tes ntsws mob qog nqaij hlav nyob rau hauv cov kev kho mob yog nqa tawm nyob rau hauv nrog cov kws khomob tshuaj Pt (tsis muaj ntau tshaj li 6 mus), thiab tom qab uas cov tshuaj siv raws li monotherapy.

koj yuav tau nres rau nkag mus rau "Avastin" Thaum koj pom tej cim ntawm kev mob cancer mob. Cov lus qhia rau kev siv lub xeev yog tias tsis muaj kev vam meej, lub xam yog 7.5 mg / kg txhua txhua 14 hnub los yog ntau npaum no nce los ntawm ib nrab thiab yog xeem ib zaug txhua txhua peb lub lis piam nyob rau hauv tas li ntawd mus rau lub "cisplatin" thiab "carboplatin".

Nyob rau hauv lub raum cell qog nqaij hlav KOOB yuav tsum tsis txhob ntau tshaj 10 mg / kg rau 15 hnub ib zaug. Yog hais tias muaj cov cim qhia ntawm kev vam meej ntawm tus kab mob, cov kev kho mob yuav tsum tau tso tseg.

Cov neeg laus tsis tas yuav tau kho cov koob tshuaj.

"Avastin": overdose

Drug overdose tshwm sim feem ntau heev nyob rau hauv cov kev tshwm sim hais tias ib tug neeg mob muaj tau xws siab koob tshuaj - 20 mg rau ib kg neeg mob lub cev hnyav txhua txhua 14 hnub.

Nyob rau hauv cov ntaub ntawv no, tej zaum yuav tshwm sim migraine tawm tsam nyob rau hauv ib tug ncaj complex daim ntawv no, nyob rau hauv tas li ntawd, muaj tau ua phiv los piav rau hauv qab no. Tshwj xeeb antidote tsis muaj nyob, tsuas symptomatic txoj kev kho yog siv.

"Avastin": phiv

"Avastin" - ib tug heev zoo tshuaj, nyob rau hauv Feem ntau nws yuav pab ua rau kom cov mob ntawm mob loj, tab sis feem ntau cov neeg mob muaj cai undesirable los. Nyob rau hauv tsawg zaus, lawv yuav ua tau heev loj:

1. Perforation ntawm lub plab thiab cov hnyuv.
2. Internal los ntshav.
3. Arterial thromboembolism.
4. Nce cov ntshav siab thiab proteinuria tsim. Feem ntau cov yuav, qhov no yog ib lub txim ntawm tus neeg mob koob cov lus teb.

Nyob rau hauv tas li ntawd, cov neeg mob uas tau teem tseg tshuaj "Avastin", tshwm sim thiab lwm cov tsos mob tshwm sim:

• sib sib zog nqus cov hlab ntsha thrombosis, ib tug complex daim ntawv ntawm lub plawv tsis ua hauj lwm, supraventricular tachycardia, los ntshav;
• leukopenia, neutropenia, tsis tshua muaj hemoglobin thrombocytopenia;
• tsis xis nyob rau hauv lub peritoneum, mob plab mob, ntshav nyob rau hauv cov quav, ib tug kab mob ua pob xua nyob rau hauv lub qhov ncauj, pos hniav los ntshav, plob tsis so tswj rhuav txhua;
• los ntshav los ntawm lub qhov ntswg, tsis muaj oxygen, pulmonary thromboembolism;
• qhuav tawv nqaij, dermatitis, cov laus tawv nqaij;
• tsis saj, sai poob phaus, syncope, migraine, mob stroke, nkees nkees;
• qhov muag plooj tsis pom kev;
• mob nyob rau hauv qhov chaw uas tus medicament yog xeem;
• los ntshav los ntawm lub tsev me nyuam, mob txeeb zig, ua ib siab qaug zog, lub cev qhuav dej.

Contraindications

Seb tag nrho cov tsim nyog "Avastin"? Testimonials hais tias qhov no yog ib qho zoo heev cov tshuaj, tab sis nws kuj muaj contraindications rau kev siv, thiab ua ntej koj pib kho mob, tus kws kho mob yuav tsum qhia koj txog lawv. Cov tshuaj yuav tsum tsis txhob muab nyob rau hauv cov nram no mob:

• yog hais tias muaj yog ib tug tshwj xeeb intolerance ntsiab active ingredient;
• Muaj kab mob ntawm lub qhov muag thiab periocular cheeb tsam;
• tshwm sim Intraocular o;
• muaj hnub nyoog ntawm 18 xyoo;
• Cev xeeb tub thiab lactation.

Nyob rau hauv tas li ntawd, yog hais tias tus neeg mob muaj ib lub caij nyoog ntawm stroke, ces prick "Avastin" muab tso rau xwb tom qab tus neeg mob ua tib zoo ntsuam xyuas thiab tuaj mus rau lub xaus hais tias cov tshuaj pab.

ceev faj

Treat tshuaj yuav tsum tsuas kws kho mob uas muaj kev ua tau zoo intraocular tshuaj.

Tom qab lub cuab tam yog tswvcuab, thaum nws yog tsis pom zoo kom tau qab lub log ntawm ib lub tsheb thiab ua hauj lwm nrog cov mechanisms thiab tag nrho vim hais tias ntawm yog dab tsi tej zaum yuav tsim nraum nrig txog kev pom teeb.

"Avastin" (cov chaw tsim tshuaj paus yog qhia nyob rau hauv cov lus qhia) yuav tsum tsuas yog muab cia rau hauv lub tub yees, thaum nyob rau hauv txhua rooj plaub nws yuav tsum tsis txhob yuav khov. Nws dispensed los ntawm cov tshuaj xwb.

Yuav ua li cas rau INTERACTIONS "Avastin" nrog rau lwm cov tshuaj?

Tshuaj "Avastin" yog incompatible nrog dextrose daws teeb meem. Tsis tas li ntawd, cov tshuaj yuav ua rau kom txoj kev pheej hmoo ntawm kev phiv tshuaj thaum noj nyob rau hauv nrog xws txhais tau tias:

• "Sunitinib malate" - tej zaum yuav tshwm sim tsim microangiopathic hemolytic anemia;
• platinum thiab taxanes - tau teeb meem ntawm kab pathologies, mob neutropenia, kev raug mob ntawm txoj kev tuag;
• "Panitumumab" thiab "Cetuximab" - tsub kom cov tshuaj lom los ntawm cov tshuaj thiab ua rau txoj kev tuag.

"Avastin" nyob rau hauv Ophthalmology

Feem ntau cov tsis ntev los no, cov ntaub ntawv nyob rau hauv lub xovxwm hais tias cov tshuaj "Avastin" siv los ntawm ophthalmologists los kho cov kab mob ntawm lub qhov muag thiab muab zoo heev tau. Tab sis yog nws? Yuav ua li cas no hais txog lub chaw tsim tshuaj paus? Yog qhov cuab tam tso cai rau koj mus tsis tau tsuas yog tso tseg txoj kev loj hlob ntawm cov qog, tab sis kuj yuav kho tau cov kab mob ntawm lub zeem muag?

Yog, nyob rau hauv qhov tseeb muaj yog cov ntaub ntawv uas yog ib co neeg mob tau hnov txog cov kev pab cuam ntawm cov tshuaj mus rau lub qhov muag, thiab twv yuav ua rau ib tug txhaj koob tshuaj tivthaiv "Avastin" nyob rau hauv lub vitreous, tiam sis lub ntsiab yog disastrous. Cov tshuaj lawv tsis tau coj tej kev kho neeg mob, on qhov tsis tooj, coj mus rau qhov tseeb hais tias cov neeg uas cia li dig muag. "Roche" lub tuam txhab tau pheej nyuab siab tias "Avastin" yuav siv tsis tau nyob rau hauv Ophthalmology, nws cov hom phiaj sib txawv.

Cov tshuaj no yog npaj los txo cov kev siv ntawm cov kev loj hlob ntawm cov hlab ntsha uas muab khoom noj rau mob cancer, yog li ib tug yuav txo tau nyob rau hauv lub qog txoj kev loj hlob khov. Uas yog vim li cas ua ntej yuav pib txoj kev kho thiab mloog unsubstantiated tswv yim zoo uas yuav tau sab laj ib tug kws kho mob.

"Avastin": counterparts

Raws li rau seb puas muaj ib tug hloov, uas yuav muaj nyob rau hauv nws cov nyob tus yeees yog tib yooj yim tshuaj, nws tsis ua rau lawv "Avastin". Analogs ntawm lub mechanism ntawm qhov kev txiav txim, thiab lawv kuj muab zoo tshwm sim nyob rau hauv tseg cia txoj kev loj hlob ntawm cov hlab ntsha thiab cov kev loj hlob ntawm ua cancer hlav. Cov muaj xws li:

• "Arzerru".
• "Campath".
• "Rituximab".
• "MabThera" thiab al.

Tab sis nws yuav tsum tau nco ntsoov tias tus kws kho mob muaj xaiv analogue.

"Avastin": cov lus teb ntawm cov neeg mob thiab cov kws kho mob

"Avastin" (phau ntawv qhia yog paub tseeb hais tias) yog ib lub xwb tshuaj uas muaj nyob rau hauv nws cov muaj pes tsawg leeg bevacizumab, nws yuav pab ua rau kom txoj kev loj hlob ntawm cov hlab ntsha pub tus mob, li no tseg cia tus kab mob no kom vam meej. Feem ntau ntawm cov kws kho mob uas saib puab ntawm tus kab mob nyob rau hauv ib tug neeg mob, lawv hais tias nyob rau hauv ib tug ob peb tshuaj noticeably tseg lub pob loj hlob, lub tseem ceeb tshaj plaws - txoj cai coj tshuaj thiab tsis muab nws nrog cov tshuaj uas nyob rau hauv ua ke nrog yuav ua rau muaj mob loj rau tus neeg mob.

Ntsiab lus, peb yuav hais rau kom paub meej tias "Avastin" (tsim - F. Hoffmann-La Roche) - ib tug zoo nkauj, uas yuav pab cas sim haum lub neej ntawm cov neeg mob nrog ua cancer hlav. Tab sis hais tias tsuas yog tsim nyog los thov nws nyob rau hauv cov nruj kev saib xyuas ntawm ib tug kws kho mob, txwv tsis pub lub txim yuav yog irreversible thiab xaus sadly.