Prostaglandin yog ... Prostaglandins (kev npaj): npe, cov nqi

Feem ntau ntawm cov txheej txheem nyob rau hauv peb lub cev nyob ntawm seb cov prostaglandins, uas yog tsim los ntawm cov ntaub so ntswg zoo. Feem ntau lawv pom tias yog cov tshuaj hormones, tab sis, lawv tsis yog. Lawv ua feem ntawm qhov chaw ntawm cov khoom siv, tom qab uas lawv raug rhuav tshem. Cov tshuaj hormone kuj ua rau lawv lub cev tsis tshua zoo thiab qaug zog tsuas yog qog ntawm cov kua qaub sab hauv, thiab tsis yog los ntawm ntau cov ntaub so ntswg.

Synthesis ntawm prostaglandins

Cia peb xav txog cov txheej txheem ntawm cov khoom tsim nyob rau hauv lub cev. Prostaglandin yog ib yam khoom tsim nyob rau hauv cov txheej txheem ntawm cov metabolism hauv arachidonic acid, lawv muaj feem xyuam rau eicosanoids. Fatty acids yog ib feem ntawm phospholipids uas muaj nyob hauv tag nrho cov ntaub so ntswg. Nyob rau hauv kev txiav txim ntawm phospholipase A2, arachidonic acid decomposes, tom qab uas nws nce nyob rau cyclooxygenase los yog lipoxygenase txoj ntawm metabolism. Prostaglandins yog cov khoom ntawm cov qub.

Lub luag haujlwm hauv lub cev yog dab tsi?

Eicosanoids ua ntau yam haujlwm. Prostaglandin yog ib yam khoom uas yuav siv ntau yam ntawm cov txheej txheem hauv peb lub cev. Piv txwv li, prostaglandin E muaj kev nyuab siab, uas yog pab kom txo cov ntshav, cuam tshuam lub suab ntawm cov hlab ntsha. Tsis tas li ntawd, prostaglandins (tshuaj thiab tej yam ntuj tso) qhib cov kev ua haujlwm ntawm qhov kev ntsuas hauv lub plawv, vim lawv siv los txhawb txoj haujlwm. Cov tshuaj no ua rau kom muaj kev nce qib hauv cov kua nplaum, uas yog tsim los ntawm goblet hlwb ntawm lub plab. Slime ua ib qho kev tiv thaiv, tiv thaiv cov nyhuv ntawm txhoj puab heev yam nyob rau hauv mucosa. Tsis tas li ntawd, cov tshuaj suppress tsim ntawm pepsin thiab hydrochloric acid, uas yog zoo siv nyob rau hauv kev kho mob ntawm plab kab mob nrog rau nce tso tawm ntawm cov tshuaj no. Lawv kuj muaj kev cuam tshuam cov rheological thaj chaw ntawm cov ntshav, inhibiting platelet aggregation. Prostaglandin E cuam tshuam rau cov leeg mob hlwb ntawm lub cev thiab cov hlab ntses, nws txhawb nqa lawv cov kev so, thiab qhov ntawd, nthuav tawm ntawm cov hlab cua. Tseem ceeb heev ntawm cov mob prostaglandins hauv mob thiab mob qhov hnyuv. Cov tshuaj no tsis tsuas yog cuam tshuam rau cov hlab ntsha thiab cov fibers, tab sis tseem koom nrog rau cov tsos mob ntawm lwm cov cim qhia ntawm qhov mob. Hloov lub suab ntawm cov hlab ntsha raws li qhov kev txiav txim ntawm prostaglandins ua rau hyperemia, thiab nce nyob rau hauv lub permeability ntawm lawv cov phab ntsa yog qhov ua rau ntawm edema tsim. Prostaglandins, nyob rau hauv tas li ntawd mus rau lub yuav muaj feem rau ntawm lub vagus paj, yuav ua tau rau kev xeev siab thiab ntuav. Nrog rau kev phiv tshuaj, cov neeg mob feem ntau ntsib. Prostaglandins - kev npaj (npe hauv qab) tsuas yog siv rau cov lus qhia nruj.

Sib cuam tshuam ntawm prostaglandins thiab anti-inflammatory tshuaj

Prostaglandin yog ib tus neeg tuaj koom rau hauv txoj kev mob nkeeg. Qhov kev txiav txim ntawm narcotics yuav muab yog raws li nyob rau hauv lub yuav txo tau ntawm synthesis (cyclooxygenase enzyme yog sim). Ntev kom ntev li ntawm NSAIDs ua rau tsis muaj prostaglandins, raws li ib qho kev tshwm sim ntawm cov teeb meem uas ua rau plab yog tus neeg tsis taus - tus thawj txo ntawm cov kua ntswg. Qhov no yog qhov tseem ceeb ntawm cov tshuaj no.

Prostaglandins - npaj: npe

Xws li cov tshuaj yog siv rau cov kab mob ntawm lub plab thiab duodenum ntawm ib qho mob erosive thiab ulcerative. Tsis tas li ntawd, lawv yog cov kws kho mob ua kom muaj kev txo hwj chim ntawm kev ntsuas ntshav thiab txhim kho txoj kev mob rheology ntawm cov ntshav.

"Misoprostol"

Prostaglandins (siv yeeb siv tshuaj) yog dav faib nyob rau hauv kev kho mob plab thiab duodenal ulcers vim lawv ua hauj lwm antisecretory. Qhov kev txiav txim no yog txuam nrog kis tau tus kab mob prostaglandin, uas nyob ntawm lub hlwb parietal ntawm lub plab. Yog li, "Misoprostol" ua cov haujlwm ntawm ntuj prostaglandin. Kev ua kom siab ntawm mucus pab tiv thaiv cov mucous membrane thiab tiv thaiv qhov tshwm sim ntawm tus kab mob tshiab qhov txhab. Tag nrho cov no kuj ua rau cov neeg mob zoo rau kev kho mob ntawm cov kab mob thiab cov ntsws.

Alprostadil

Cov tshuaj yog ib qho kev npaj ntawm prostaglandin E. Feem ntau nws tau sau rau cov mob no thaum nws raug tseev kom txo qhov kev txo hwj chim ntawm myometrium - lub zog ntawm kev ua haujlwm. Tsis tas li ntawd, cov tshuaj siv los txhim kho cov ntshav - kev tiv thaiv ntawm platelet aggregation thiab vasodilation (nrog atherosclerosis). Muaj nyob rau hauv ampoules rau intravenous administration.

Contraindications

Ob qho tshuaj tsis muaj cov tshuaj yog tias muaj kev sib thooj ua rau cov mob prostaglandins, nrog rau cov kab mob ntawm cov tshuaj no. Ntawm qhov contraindications - lub hnub nyoog 18, cev xeeb tub thiab lub sijhawm pub mis niam. Tsis tas li ntawd, lawv raug nrog ceev faj txog mob hawb pob thiab mob ntsws, mob ntsws ntawm qhov kev ua mob hauv endocrine, enterocolitis, anemia.

Self-administration ntawm prostaglandin preparations tsis tau kev pab tswv yim ib tus kws kho mob tshwj xeeb. Tsuas yog tus kws kho mob tuaj yeem xaiv cov khoom noj kom zoo thiab kho txoj hauv kev kho mob, xam cov kev xav ntawm tus neeg mob. Nyob ntawm qhov chaw ntawm kev yuav khoom, tus nqi yuav hloov. Prostaglandin yog muaj nyob rau hauv ntau yam ntaub ntawv thiab nyob rau hauv ntau yam tshuaj uas nrov npe, nws kuj muaj feem xyuam rau tus nqi.

Tej Teebmeem

Feem ntau, thaum noj cov tshuaj, muaj kev ua txhaum ntawm lub plab zom mov - xeev siab, ntuav, raws plab thiab cov mob plab dyspeptic. Yog hais tias koj yog tsis haum, cim pruritus, tawm pob, lossis puas liab liab thiab o, thiab tau anaphylactic tshua. Kev noj tshuaj muaj peev xwm ua raws nrog kev ua txhaum ntawm kev phiv sij qis, dysmenorrhea. Txo cov kabmob ntuav hauv plab feem ntau yog tshwm sim los ntawm kev mob nkeeg hauv plab plab. Lwm cov kev mob tshwm sim muaj xws li kiv taub hau, mob taub hau, kev hloov hauv lub cev qhov hnyav.

Txoj kev pheej hmoo ntawm kev phiv yog ib tus neeg rau txhua tus neeg mob. Thaum tsom pom zoo li no tshwm sim, koj yuav tsum tau nrog koj tus kws kho mob tham thiab hloov kho qhov kev npaj kho mob.

Prostaglandin yog ib yam khoom uas tsim nyog hauv kev kho mob ntawm peptic ulcer thiab lwm yam kab mob. Feem ntau lawv tau siv nrog lwm cov tshuaj los ua kom tiav qhov kev xav tau. Kev xaiv cov tshuaj thiab nws cov khoom noj yog nyob ntawm seb cov ntaub ntawv kho mob thiab tus yam ntxwv ntawm tus neeg mob.