"Mesipol": cov lus qhia rau kev siv, tiag tiag counterparts

Yuav ua li cas yog cov tshuaj "Mesipol"? nyob rau hauv daim ntawv thov ntawm lub cuab tam phau ntawv no, nws contra-indications thiab yuav tsum tau tham nyob rau hauv no tsab xov xwm. Tsis tas li ntawd, koj yuav kawm tau seb puas los yog tsis cov tshuaj no phiv uas yuav nyob rau hauv cov kev tshwm sim ntawm ib tug overdose, rau hauv daim ntawv nyob rau hauv uas nws yog marketed li cas thiab lub tshuaj muaj.

Daim ntawv ntawm cov tshuaj thiab nws muaj pes tsawg leeg

Kev npaj "Mesipol" yog marketed nyob rau hauv ob tug sib txawv cov ntaub ntawv: ntsiav tshuaj thiab cov tshuaj rau cov intramuscular txhaj tshuaj. Lawv khiav hauj lwm hauv paus ntsiab lus yog tib yam. Yog hais tias nws yog tsis yooj yim sua qhov ncauj cov thawj coj, txhaj tshuaj no yog siv.

Cov tshuaj "Mesipol" muaj ib tug active caij xws li meloxicam. Nws kuj muaj xws li cov nram qab no koom haum pab khoom xyaw: glycofurol, meglumine, sodium tshuaj dawb, Poloxamer 188, sodium hydroxide, glycine, thiab dej rau txhaj tshuaj.

Cov tshuaj muaj ib tug daj los yog greenish-daj. Nws yog pob tshab. Tsis tas li ntawd nws muaj ib tug yam ntxwv tsw. Lub thawv yog 3 ampoules (1.5 ml).

Incidentally, nyob rau hauv tas li ntawd mus ntsiav tshuaj los sis kev daws teeb meem rau intramuscular tshuaj, kws tuam txhab uas muag pib tsim taws tswm ciab "Mesipol" thiab ncua npaj rau qhov ncauj thawj coj.

Lub pharmacological cov yam ntxwv ntawm cov tshuaj

"Mesipol" tshuaj yog ib tug nonsteroidal anti-inflammatory tus neeg saib xyuas. Cov tshuaj yog tau pheev analgesic thiab antipyretic nyhuv. Lub antiinflammatory nyhuv ntawm cov txhais tau tias txuam nrog ib tug slowing ntawm lub enzymatic kev ua ntawm cyclooxygenase-2, uas yog muab kev koom tes nyob rau hauv lub biosynthesis ntawm prostaglandins nyob rau hauv lub kub lug cheeb tsam.

Lub kawg active meloxicam caij ua rau cyclooxygenase-1, uas yog ncaj qha mus muab kev koom tes nyob rau hauv prostaglandin synthesis, uas tiv thaiv lub txheej membrane ntawm cov hnyuv thiab ua rau cov kev cai ntawm cov ntshav khiav tsis zoo hauv lub raum.

Tshuaj ntawm cov tshuaj

Tshuaj "Mesipol" (tshuaj thiab cov ntsiav tshuaj) yog absorbed kiag li. Lub bioavailability ntawm cov tshuaj yog 100%. Tom qab intramuscular txhaj tshuaj (li ntawm 15 mg meloxicam), lub siab tshaj plaws haum yog mus txog tom qab 65 feeb.

peb xav tias yuav cov tshuaj uake rau ntshav cov nqaijrog, xws li albumin (99%). Nws yooj yim kis los ntawm cov ntshav-cov ntaub so ntswg tej, tab sis kuj penetrates mus rau hauv lub synovial cov kua. Lub concentration therein yog 50% ntawm cov tshuaj nyob rau hauv concentration ntshav.

Lub active tshuaj ntawm medicament yog yuav luag tag metabolized nyob rau hauv lub siab. Qhov no ntaub ntawv plaub pharmacological tsaug zog metabolite.

Tom qab daim ntawv thov ntawm cov medicament Attendance tso tawm kom pom hnyuv thiab lub raum (a metabolite). Qhov nruab nrab ib nrab-lub neej ntawm lub active tshuaj yog 20 teev.

Indications rau ntawm kev noj tshuaj

Nyob rau hauv tej rooj plaub, muab "Mesipol"? Cov lus qhia rau Siv lub xeev uas feem ntau pom zoo kom siv cov narcotics yuav muab nyob rau hauv lub symptomatic kev kho mob ntawm cov kab mob xws li:

• osteoarthritis;
• mob caj dab rheumatoid;
• Ankylosing spondylitis (los yog ankylosing spondylitis).

Nyob rau hauv tas li ntawd, cov tshuaj "Mesipol" (tshuaj thiab cov ntsiav tshuaj) yog feem ntau kws kho rau lwm degenerative thiab inflammatory kab mob ntawm cov pob qij txha, uas yog nrog mob heev.

Contraindications rau kev siv uas tsis yog-tshuaj cov neeg ua hauj

Nyob rau hauv tej rooj plaub, tshuaj yuav siv tsis tau "Mesipol"? Cov lus qhia rau kev siv muaj ib tug lossis loj daim ntawv teev cov contraindications. Cov no muaj xws li nram qab no:

• Npau taws me ntsis rau lub active keeb ntawm cov tshuaj los yog cov koom haum pab Cheebtsam;
• feem los sis tag thaum lawv tseem mob hawb pob, intolerance ntawm acetylsalicylic acid, polyposis (recurrent) paranasal qhov ntswg thiab qhov ntswg kab noj hniav, thiab lwm yam narcotics yuav muab, nrog rau cov anamnesis;
• cov me nyuam uas muaj hnub nyoog (16-18 xyoo);

• ulcerative los yog erosive txhab ntawm lub qog ua kua membrane 12 tiperstnoj hnyuv los yog lub plab;
• kev pub niam mis;
• cerebrovascular los ntshav los yog lwm yam los ntshav keeb kwm;
• active los ntshav nyob rau hauv lub gut los yog plab;
• thaum lub sij hawm hnub (cev xeeb tub);
• inflammatory plob tsis so tswj kab mob (e.g. Crohn tus kab mob los yog ulcerative mob plab);
• hnyav raum tus kab mob, nrog rau hyperkalemia (paub tseeb hais tias);
• lub sij hawm tom qab coronary artery bypass phais;
• raum tsis ua hauj lwm (expressed) nyob rau hauv cov neeg uas tsis tau raug lim ntshav (CC tsawg tshaj li 30 ml / min);
• decompensated lub plawv tsis ua hauj lwm;
• active kev vam meej ntawm daim siab tus kab mob los yog siab tsis ua hauj lwm (mob loj heev).

Siv nrog huab ceev faj!

Tam sim no uas koj paub nyob rau hauv uas tus neeg mob koj muaj peev xwm siv cov tshuaj "Mesipol" (ntsiav tshuaj, tshuaj), thiab nyob rau hauv uas nws yog txhob. Txawm li cas los, muaj tej yam teeb meem uas peb tau kawm tshuaj yuav tsum tau muab nrog huab ceev faj. Xav txog daim ntawv teev cov xws li mob:

• advanced muaj hnub nyoog (60 xyoo);
• coronary mob plawv;
• mob hauv lub plawv tsis ua hauj lwm;
• cerebrovascular kab mob;
• mob ntshav qab zib;
• dyslipidemia los yog hyperlipidemia;
• peripheral leeg kab mob;
• creatinine clearance tsawg tshaj li 60 mL / min;
• haus luam yeeb;
• ulcerative txhab ntawm lub digestive system nyob rau hauv keeb kwm;
• long-term siv uas tsis yog-tshuaj tshuaj, raws li zoo raws li lawv uncontrolled siv nyob rau hauv loj koob tshuaj;
• ib tug kab mob, lub npe hu ua Helicobacter pylori;
• noj nqos tau cov dej haus cawv (txawm nrog ib tug tsawg cov ntsiab lus ntawm cov cawv);
• ib-lub sij hawm siv ntawm qhov ncauj corticosteroids, xws li "Prednisolone" tshuaj;
• mob loj heev Somatic txawv txav;
• concomitant siv anticoagulants (e.g., tshuaj "warfarin"), antiplatelet agents (e.g., acetylsalicylic acid thiab ib tug medicament 'Clopidogrel') raws li tau zoo raws li inhibitors (xim) serotonin reuptake (xws li cov tshuaj "Tsitmedialopram", "Fluoxetine", "paroxetine" thiab "sertraline").

Nonsteroidal anti-inflammatory siv yeeb tshuaj "Mesipol": cov lus qhia rau kev siv

Intramuscular thawj coj ntawm lub medicament ua ntej peb pom tsuas yog rau cov thawj 3 hnub ntawm kev kho mob. Nyob rau hauv lub neej yav tom ntej, txuas ntxiv mus kho nrog qhov ncauj ntaub ntawv ntawm cov tshuaj, piv txwv li ntsiav tshuaj.

Cov pom zoo ntau npaum ntawm tus neeg saib xyuas yog 7.5 mg los yog 15 mg ib zaug ib hnub twg. Ib tug muab ntau npaum li cas ntawm cov tshuaj nyob rau hauv lub khov ntawm qhov mob, raws li tau zoo raws li lub heev ntawm lub inflammatory txheej txheem. Lub medicament yog muab los ntawm sib sib zog nqus intramuscular txhaj tshuaj.

Yog nws tau mus ua ke nrog lwm yam tshuaj tshuaj "Mesipol" (tshuaj)? Instruction ntawm cov tshuaj hais tias tus txheem ntawm lub vials nyob rau hauv txhua rooj plaub yuav tsis tau tov nyob rau hauv tib lub koob txhaj nrog rau lwm cov kev daws teeb meem. Qhov no yog vim lub fact tias muaj yog ib tug siab ntau yam ntawm incompatibility ntawm lub active tshuaj meloxicam nrog rau lwm cov kev kho mob yam.

Nws yuav tsum tau muab sau tseg tias nyob rau hauv cov neeg mob uas muaj kev raug mob ntawm cov nyom tshua, raws li zoo raws li lub raum tsis ua hauj lwm (expressed) nyob rau hemodialysis, ib tug nonsteroidal tshuaj ntau npaum yuav tsum tsis txhob muaj ntau tshaj li 7.5 mg ib hnub twg.

Nws tseem yog tsim nyog yuav tau nco ntsoov hais tias cov tshuaj "Mesipol", analogues ntawm uas peb yuav tsum xav txog ntxiv lawm, nyob rau hauv txhua rooj plaub yuav tsum tsis txhob muab intravenously.

Qhov siab tshaj plaws txhua txhua hnub koob tshuaj meloxicam active caij yuav tsum tau 15 mg. Cov nqi qub medicament yuav tsum tau ua raws li thiab lub neej coj siv cov ntsiav tshuaj, ncua, rau qhov ncauj cov thawj coj, suppositories, thiab intramuscular txhaj tshuaj.

tus neeg mob ntawm overdose

Puas muaj tus neeg mob ntawm overdose los ntawm kev siv ntawm "Mesipol" tshuaj? Tshuaj (xyuas txog lawv yuav tsum tau nthuav tawm nyob rau thaum xaus ntawm qhov tsab xov xwm), tshuaj, suppositories thiab ncua tej zaum yuav ua rau koj cov tib neeg hais tias yog siv uncontrollably thiab nyob rau hauv loj tagnrho.

Cov tsos mob ntawm overdose yuav muaj xws li cov nram qab no tej yam kev mob: xeev siab, impaired nco qab, epigastric mob, mob raum tsis ua hauj lwm, ntuav, los ntshav nyob rau hauv lub plab los yog cov hnyuv, lub siab tsis ua hauj lwm, asystole, thiab ua pa raug ntes.

Yuav ua li cas nyob rau hauv cov ntaub ntawv ntawm ib tug overdose? Kws txawj pom zoo kom pais plab lavage, raws li zoo raws li ib tug symptomatic txoj kev kho.

Los ntawm txoj kev, nyob rau hauv lub chav kawm ntawm kev tshawb fawb pom tau hais tias cholestyramine pab leeb txoj kev tshem tawm ntawm meloxicam. Hemodialysis overdose yog ices, txij li thaum muaj ib tug siab kev twb kev txuas rau cov ntshav proteins.

phiv

Nws yuav ua rau kev phiv tshuaj "Mesipol" (tshuaj)? nyob rau kev siv uas tsis yog-tshuaj cov neeg ua hauj Guide hais tias nws muaj peev xwm ua rau ib tug loj tus naj npawb ntawm zoo txim. Cia peb xav txog lawv nyob rau hauv ntau yam:

• Hnyuv: dyspepsia, raws plab, xeev siab, perforation ntawm cov hnyuv, mob plab, ntuav, flatulence, cem quav, nraum nce nyob rau hauv transaminases (daim siab), burp, hyperbilirubinemia, ulcerative los yog erosive txhab ntawm lub digestive system, esophagitis, stomatitis, qhia tau meej heev los yog muab zais los ntshav los ntawm cov hnyuv, mob plab, gastritis thiab kab mob siab.
• Ntawm daim tawv nqaij: pob, pruritus, bullous pob, daim tawv nqaij ua pob liab vog, photosensitivity, Stevens-Johnson syndrome, erythema multiforme, epidermal necrolysis lom.
• hemopoietic system: anemia, thrombocytopenia, kev hloov nyob rau hauv cov ntshav suav thiab leukopenia.
• Kev tsis haum tshuaj: angioedema , thiab anaphylaxis.
• Tshee System: Kiv tauv hau, kiv taub hau, tsis meej pem, mob taub hau, kev xav lability, tinnitus, tsis meej pem thiab nkees nkees.
• Ua pa system: bronchospasm.
• Plawv system: ib tug maj ntawm cov ntshav mus rau lub daim tawv nqaij, peripheral edema, palpitations thiab ntshav siab.
• Kabmob uas tsis pom kev: qhov muag plooj los yog tsis hnov tsis pom kev, conjunctivitis.
• Mob txeeb system: mob raum tsis ua hauj lwm, hypercreatininemia los yog nce nyob rau hauv cov ntshav urea, interstitial nephritis, hematuria thiab albuminuria.
• Local tshua: mob thiab kub ntawm qhov chaw ntawm intramuscular txhaj tshuaj.

Sis nrog lwm yam tshuaj

• Thaum ib tug-lub sij hawm siv ntawm lwm nonsteroidal tshuaj thiab acetylsalicylic acid tsub kom kev pheej hmoo ntawm lub rwj thiab erosive txhab ntawm lub digestive ib ntsuj av tau, raws li tau zoo raws li los ntshav nyob rau hauv lawv.
• Nrog rau cov simultaneous siv ntawm cov tshuaj nrog antihypertensives yog yuav txo tau cov hauj lwm zoo ntawm lub yav tas.
• Tib mus kho mob tshuaj "Mesipol" nrog lithium txoj kev kho yeej txhawb txuam nrog ntawm lub yav tas thiab ua rau kom nws cov tshuaj lom los.
• Thaum ib tug-lub sij hawm daim ntawv thov ntawm "Methotrexate" txhais tau tias kom nws phiv rau lub hematopoietic system.
• Tib mus siv ntawm cov tshuaj "Mesipol" nrog diuretics yog kev pheej hmoo ntawm lub raum tsis ua hauj lwm.
• Ib-lub sij hawm siv nrog cyclosporine tsub kom lub nephrotoxic los ntawm lub active tshuaj meloxicam.
• Nrog rau cov simultaneous siv rau cov intrauterine contraceptives txo cov hauj lwm zoo ntawm lub yav tas.
• Thaum ib tug-lub sij hawm siv ib tug anticoagulant thiab thrombolytic cov neeg ua hauj tsub kom qhov uas yuav los ntshav.
• Tib mus siv ntawm ib tug uas tsis yog-tshuaj tshuaj "Mesipol" nrog kolestiraminom tej nws feem ntawm cov hnyuv kabmob. Qhov no tshwm sim raws li ib tug tshwm sim ntawm thwj toob ntawm meloxicam.
• Pov tseg rau hauv lub tshuaj nrog inhibitors ntawm (xim) serotonin reuptake ho tsub kom kev pheej hmoo ntawm los ntshav los ntawm cov hnyuv ib ntsuj av.
• Myelotoxic tshuaj ua rau kom cov kev qhia gematotoksichnosti active tshuaj meloxicam.

Cov kev taw qhia nyob rau kev siv ntawm cov tshuaj

• Tshuaj "Mesipol" yuav tsum nrog huab ceev faj nyob rau hauv cov neeg mob uas peptic rwj ntawm lub plab thiab cov hnyuv, raws li zoo raws li cov neeg uas muaj nyob rau hauv anticoagulant txoj kev kho.
• Thaum lub sij hawm kev kho mob nrog cov tshuaj no tsim nyog los tswj cov tsis ntawm lub raum muaj nuj nqi, tshwj xeeb tshaj yog nyob rau hauv cov neeg laus thiab cov neeg mob uas mob hauv lub plawv tsis ua hauj lwm.
• Cov neeg mob ib txhij tau txais diuretics thiab txhais tau tias "Mesipol", yuav tsum tau haus dej kom ntau.
• Yog hais tias nyob rau hauv lub chav kawm ntawm kev kho, tus neeg mob nyob ua xua, cov tshuaj ntawm tshuaj yuav tsum tau txiav.

Analogues thiab cov tshuaj nqi

Yuav ua li cas npaum li cas yog peb pom tau hais tias ib tug yeeb tshuaj? Lub tsev muag tshuaj txhaj daim ntawv ntawm cov tshuaj yuav tau muas 400 Lavxias teb sab rubles. Raws li rau cov ntsiav tshuaj, ncua thiab suppositories, lawv cov nqi yog ib tug me ntsis tsawg dua.

Yuav ua li cas yog hais tias koj tsis yuav cov tshuaj "Mesipol"? Analogs ntawm cov nyiaj yog muag nyob rau hauv yuav luag tag nrho cov drugstores. Ntawm lawv yog cov nram qab no tshuaj: "Amelotex", "Eksen-Sanovel", "Artrozan", "Matar", "M-Cam," "dawb", "Medsikam", "Melbek", "Melox", "txawj hais ob Xico "," Meloxicam "," Melox "," Meloflam "," Miksol-Aude "," Mirloks "," Movalis "," Movasin "," Moviks "," Lem "," Oksikamoks "thiab thiaj on.

"Mesipol": xyuas ntawm medicament

Tam sim no koj paub tias yog ib tug yeeb tshuaj peb xav. Nws yog lub sij hawm mus nrhiav seb yog dab tsi cov neeg mob hais txog "Mesipol" kev npaj. Xyuas ntawm no nonsteroidal anti-inflammatory ambiguous txhais tau tias. Nyob rau hauv ib tes, cov neeg mob tau thov hais tias nws yog zoo relieves mob syndromes uas yog xam qhovkev nyob rau hauv osteoarthritis, mob caj dab rheumatoid, ankylosing spondylitis thiab lwm yam degenerative thiab inflammatory kab mob ntawm cov pob qij txha. Nyob rau lwm cov tes, cov neeg mob feem ntau txaus siab hais tias cov tshuaj yuav ua rau ib tug ncaj loj tus naj npawb ntawm cov kev phiv, raws li ib tug tshwm sim ntawm uas lawv raug yuam kom tsis txhob noj nws.

Nyob rau hauv dav dav, lub yeeb tshuaj ua ntej peb "Mesipol" kiag li copes nrog nws ua hauj lwm.