Anti-tshuaj tshuaj: hauj lwm, daim ntawv thov

Estrogen-blockers yog tshuaj tebchaw uas thaiv qhov kev txiav txim ntawm cov tshuaj no. Antiestrogen cov tshuaj siv nyob rau hauv cov kev kho mob ntawm ntau yam kab mob. Lawv yog lug siv rau cov kev kho mob ntawm cancer ntawm lub mis dab inhibit lub pob loj hlob los yog relapse kev tiv thaiv. Raws li yog cov ntaub ntawv nrog rau lwm cov tshuaj uas nrog cov tshuaj hormones rau hauv lub cev, cov tshuaj yuav tsum tau siv nyob rau hauv kev kho mob saib xyuas.

Cov kev pab cuam thiab harms ntawm cov tshuaj no

Estrogen, los yog ib tug steroid lawm tsim los ntawm lub zes qe menyuam. Nws muaj feem xyuam rau ib tug xov tooj ntawm kev ntawm lub cev. Cov poj niam uas nyuam uas muaj hnub nyoog muaj lub siab tshaj plaws theem ntawm cov tej yam tshuaj. Ib tug ntau npaum li cas, txawm li cas los, tej zaum yuav ua rau ib tug syndrome lub npe hu ua hyperestrogenia. Tus kab mob no yuav ua tau kom mob cancer txheej txheem nyob rau hauv lub mis thiab endometrial cancer. Anti-tshuaj tshuaj thiab cov tshuaj no blockers thiab aromatase inhibitors yuav nws kho txhua yam. Cov tshuaj, txawm li cas los, muaj zoo thiab tsis zoo ua li cas rau cov poj niam thiab cov txiv neej.

Hom tshuaj no-blockers thiab lawv cov kev siv

Muaj ib tug xov tooj ntawm ntau hom ntawm cov tshuaj no-blockers. aromatase inhibitors tau thaiv zus tau tej cov tshuaj no. Xaiv cov tshuaj no receptor modulators, xws li "tamoxifen" "Clomiphene", tsim los thaiv cov tshuaj no receptors, thiab coj txawv rau ntau yam ntawm cov ntaub. Antiestrogens kuj thaiv cov tshuaj no receptors.

Antiestrogens tiv thaiv kom txhob hloov dua siab tshiab ntawm testosterone rau estradiol thiab cov tshuaj no cov tshuaj hormones tsum ua hauj lwm los yog atherosclerosis.

Nyob rau hauv kev kho mob cancer, cov tshuaj yog siv los qeeb txoj kev loj hlob ntawm cov qog. Nyob rau hauv cov ntaub ntawv no, xim cov tshuaj no receptor modulators yuav tsom kom meej cov tshuaj no receptors. Blockers, xws li "Clomiphene" tej thaum kuj siv nyob rau hauv cov kev kho mob ntxiv lawm tshob, tej zaum lawv yuav pab tau ib txhia poj niam uas muaj kev nyuaj ua cev xeeb tub. Cov tshuaj no kuj siv los ntawm ib co clinicians nyob rau hauv cov kev kho mob ntawm cov me nyuam nrog ncua tiav nkauj tiav nraug kom txog rau thaum lawv yog cov qub txaus.

Cov bodybuilders nws tau siv ntawm cov tshuaj no-blockers vim hais tias ntawm lub estrogenic nyhuv ntawm theem ntawm testosterone nyob rau hauv lub cev. Testosterone yog ib tug precursor ntawm ib tug cov tshuaj no, aromatase inhibitors yuav siv tau kom tsis txhob tsim ntawm nqaij loj tshaj ntawm cov tshuaj no, kev tswj ib tug tsawg theem nyob rau hauv lub cev. Qhov no tau attracted ntau, tshwj xeeb tshaj yog thaum anti-tshuaj tshuaj yog siv feem ntau rau niaj hom phiaj. Nyob rau hauv cov ntaub ntawv no, cov neeg siv cov ntsiav tshuaj thiab kev pab noj haus tsis muaj kev kho mob saib xyuas.

phiv

Muaj tshwm sim los ntawm anti-tshuaj tshuaj. Lawv muaj peev xwm ua rau kiv taub hau, mob taub hau, tawm hws, kub flashes thiab tsis meej pem. Tsuas yog endocrinologist yuav txiav txim rau qhov tsim nyog ntau npaum rau ib tug neeg mob nyob rau qhov teeb meem no, thiab ib tug siv tau pib ntawm kev phiv. Lub endocrinologist kuj muab kev kuaj ntshav rau lawm ntau ntau thaum nrug muaj feem luj lub zuag qhia tag nrho noj qab haus huv ntawm tus neeg mob kom paub tseeb tias kev siv ntawm anti-estrogens muaj kev ruaj ntseg thiab kev haumxeeb rau tus neeg mob.

cov txiv neej kev kho mob

Nrog lub hnub nyoog, txiv neej testosterone ntau ntau poob. Txawm li cas los, Yog hais tias testosterone yog sai sai los yog zoo heev txo, nws yuav ua rau txoj kev loj hlob ntawm hypogonadism. Lub xeev no yog yus muaj los ntawm lub cev tsis muaj peev xwm yuav tsim no tseem ceeb lawm, yuav ua rau ib tug ntau yam ntawm cov tsos mob, xws li:

• tsis libido;
• yuav txo tau ntawm ntau lawm thiab zoo ntawm cov phev;
• erectile kawg;
• qaug zog.

Yog hais tias peb tham txog cov tshuaj no, yog thawj zaug uas neeg xav hais tias nws yog ib tug poj niam lawm, tab sis nws muaj kom hais tias tus txiv neej lub cev yog ua tau hauj lwm zoo. Muaj peb hom kev estrogens: estriol, estrone thiab estradiol. Estradiol - yog qhov tseem ceeb hauv daim ntawv ntawm active tshuaj nyob rau hauv cov txiv neej. Nws plays ib tug tseem ceeb heev luag hauj lwm nyob rau hauv kev tswj cov kev ua ntawm tus txiv neej cov pob qij txha thiab lub hlwb cov ntaub so ntswg. Antiestrogen tshuaj kuj tso cai rau lub phev los tsim kom zoo.

Hormonal tsis txaus - raising rau cov theem ntawm cov tshuaj no thiab tsis testosterone - tsim teeb meem. Ntau dhau lawm estrogen nyob rau hauv tus txiv neej lub cev muaj peev xwm ua rau:

• gynecomastia (ntev li ntawm kev loj hlob ntawm lub mis cov ntaub so ntswg);
• plawv muaj teeb meem;
• kev raug mob ntawm ib tug mob stroke;
• qhov hnyav nce;
• Teeb meem nrog tus prostate.

Koj muaj peev xwm coj ob peb kauj ruam los tshuav nyiaj li cas nyob rau hauv lub theem ntawm cov tshuaj no. Piv txwv li, yog tias koj tshaj tshuaj yog txuam nrog tsawg theem ntawm testosterone, uas yuav pab tau raws li ib tug testosterone hloov txoj kev kho ntawm cov tshuaj no blocker.

Kws tshuaj-blockers

Ib txhia kws tshuaj yuav ua tau cov tshuaj no-thaiv cov hlab cov nyhuv rau cov txiv neej. Raws li txoj cai, feem ntau lawv yog npaj rau kev siv los ntawm cov poj niam, tab sis yog muaj nyob rau hauv muaj koob meej ntawm cov txiv neej, tshwj xeeb tshaj yog rau cov neeg uas xav kom muaj cov me nyuam. Testosterone tshuaj tej zaum yuav ua rau ntxiv lawm tshob. Tab sis cov tshuaj no blockers xws li "Clomid" yuav restore hormonal tshuav nyiaj li cas tsis muaj compromising fertility.

Ob peb tshuaj lub npe hu ua xim estrogen receptor modulators, feem ntau marketed li tshuaj rau cov kev kho mob cancer ntawm lub mis. Tab sis lawv muaj peev xwm kuj yuav siv los thaiv cov tshuaj no nyob rau hauv cov txiv neej. Cov tshuaj no siv tau rau ib tug ntau yam ntawm tej yam kev mob uas muaj feem rau cov uas tsis muaj testosterone, xws li:

• ntxiv lawm tshob;
• tsawg phev suav;
• gynecomastia;
• txha.

Cov tshuaj yuav tsum tau siv xyua, nyob ntawm seb tus neeg mob. Siv xws anti-tshuaj tshuaj. Thaum lub tsev muag tshuaj koj yuav tau:

• "Tamoxifen".
• 'Arimidex'.
• "Letrozole."
• "Raloxifene".

Los rau cov pob txha

Raws li clinicians, heev raug rau cov tshuaj no tshuaj yuav ua rau endometrial cancer nyob rau hauv cov poj niam. "Raloxifene" - ib tug xim estrogen receptor modulator - yuav tiv thaiv tau txoj kev loj hlob ntawm cancer, xaiv blocks haum ntawm cov tshuaj no. Qhov no yeeb tshuaj, txawm li cas los, yog tseem muaj peev xwm sawv ntawm inhibiting qhov zoo los ntawm cov tshuaj no rau tus pob txha ceev. Cov tshuaj tshiab - "lasofoxifene" - tej zaum yuav kho qhov teeb meem no. Nws tiv thaiv tsis tau ntawm tus pob txha ceev nyob rau hauv postmenopausal cov poj niam thiab thiaj li brittleness ntawm cov pob txha cov ntaub so ntswg. Kev siv cov tshuaj no yog feem ntau muaj kev ruaj ntseg, tab sis tej zaum yuav ua rau kom cov ntshav txhaws.

tshuaj cov kev sib tshuam

Estrogen blocker "tamoxifen" yuav pab tiv thaiv tau cancer. Cancer cov neeg mob feem ntau muaj kev nyuaj siab, thiab qhov no pab pawg neeg ntawm cov tshuaj tej zaum yuav INTERACTIONS tshuam nrog rau cov tshuaj, antidepressants. Yuav tsum tau thov "Paroxetine", vim lub fact tias cov poj niam noj "tamoxifen" thiab "Paroxetine", tsawg pheej hmoo ntawm kev tuag tshaj cov poj niam uas coj "tamoxifen" thiab lwm yam kev nyuaj siab. Qhov no yog vim hais tias "Paroxetine" ua xyua.

Antiestrogen neeg thiab cov tshuaj

Cov qhia tawm ntawm tag nrho cov ntawm cov nyiaj no qhia tau tias txhua cov tshuaj no yog siv ib lub zuj zus nyob rau hauv ib tug cov ntaub ntawv.

"Clomid" los yog "clomiphene citrate" yog ib tug ntawm cov thawj cov tshuaj siv nyob rau hauv cov kev kho mob ntawm gynecomastia, vim hais tias nws seb puas tsimnyog tau rau hauv lub cev theem ntawm tej yam ntuj tso testosterone. Muaj ib co sab los ntawm ntev-lub sij hawm pab, xws li tsis pom kev cov teeb meem. Muaj ntau ntau zoo tshuaj nyob rau hauv kev ua lag luam, uas ua nyob rau hauv tib txoj kev tab sis "Clomid" yog tseem zoo thiab pheej yig mix rau tej kis las.

Qhov no tsis yog ib qho anabolic steroid, ib tug yeeb tshuaj feem ntau tus kws kho raws li ib qho kev pab nyob rau hauv cov poj niam nrog ntxiv lawm tshob, vim hais tias nws muaj ib tug qhia tau muaj peev xwm mus tsim kho ovulation, uas yog tiav los thaiv cov hlab / nrhiav cov teebmeem ntawm cov tshuaj no nyob rau hauv lub cev. Yuav kom ua tau ntau tshaj ib qho, "Clomid" - tshuaj thaj chaw ntawm cov khoom cua cov tshuaj no agonist / antagonist. Nyob rau hauv tej yam hom phiaj ntaub so ntswg nws yuav thaiv lub peev xwm ntawm cov tshuaj no rau khi rau cov coj receptor. Nws soj ntsuam kev siv yog rau counter qhov tsis zoo tswv yim ntawm cov tshuaj no nyob rau hauv lub hypothalamus-pituitary-ntawm zes qe menyuam system, uas txhim khu qhov kev tso tawm ntawm LH thiab FSH. Tag nrho cov no ua rau yus ovulation.

Rau ntaus pob ncaws pob hom phiaj "clomiphene citrate" poj niam muaj tsis ntxim. Nyob rau hauv cov txiv neej, txawm li cas los, muaj yog nce zus tau tej cov FSH thiab (feem ntau) luteinizing hormone uas nkoos ntuj testosterone. Cov nyhuv no yog tshwj xeeb tshaj yog pab tau mus rau lub neeg ncaws kab taub qhov kawg ntawm ib tug steroid voj voog thaum endogenous testosterone ntau ntau muaj kev nyuaj siab. Yog tsis muaj testosterone (los yog lwm yam androgens), "Cortisol" prevails thiab muaj feem xyuam rau cov protein ntau synthesis nyob rau hauv cov nqaij. Tab sis nws sai sai "noj" feem ntau ntawm cov tshiab khiv nrhav nqaij tom qab tshem tawm. Clomid yuav ua si ib tug tseem ceeb luag hauj lwm nyob rau hauv kev tiv thaiv no tsis ua hauj lwm mus cuag cov kev ua si tau. Rau cov poj niam, cov kev pab cuam ntawm kev txiav txim Clomid - Muaj peev xwm kom tswj tau tus endogenous tshuaj theem. Qhov no yuav ua rau kom tsis muaj roj thiab nqaij, tshwj xeeb tshaj yog nyob rau hauv tej thaj chaw xws li lub ncej puab thiab pob tw. "Clomiphene citrate", txawm li cas los, feem ntau ua phiv nyob rau hauv cov poj niam, tab sis, cuaj kaum, thov cov no pab pawg neeg ntawm ncaws pob.

"Tamoxifen" thaiv cov hlab cov tshuaj no receptors nyob rau hauv lub mis mob cancer hlwb. Qhov no tsis cov tshuaj no los ntawm interacting nrog lawv thiab tiv thaiv cov kev loj hlob thiab division ntawm lub hlwb. Thaum "tamoxifen" ua li ib qho antiestrogen nyob rau hauv lub mammary caj pas hlwb, nws ua raws li ib tug tshuaj nyob rau hauv lwm yam ntaub so ntswg: pob txha thiab lub tsev me nyuam.

Cov poj niam uas nyob mis "tamoxifen" tus mob cancer yuav siv tau rau 5-10 xyoo tom qab lub lag luam, los txo qhov yuav ua rau metastasis nthuav. Nws kuj thiaj li txoj kev pheej hmoo ntawm mob cancer nyob rau hauv lub mis. Rau thaum ntxov rau theem ntawm kev npaj no yog siv rau cov neeg mob uas ua tsis tau lawm. Aromatase inhibitors yog cov nyiam kev kho mob rau menopausal cov poj niam.

"Tamoxifen" tej zaum kuj tsis txhob txoj kev loj hlob los yog txawm ntsws hlav nyob rau hauv cov neeg mob uas metastatic neeg mob cancer. Nws kuj yuav siv tau los txo cov kev pheej hmoo ntawm lub mis onkologicheskihz dab.

Qhov no tshuaj yog coj hais lus, feem ntau yog nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj.

Phiv los ntawm anti-tshuaj tshuaj muaj xws li: nkees, kub flashes, paum dryness los yog copious thiab mus ob peb vas swings.

Ib txhia poj niam nrog metastases nyob rau hauv cov pob txha cov ntaub so ntswg yuav tshwm sim qhov mob thiab o nyob rau hauv cov nqaij thiab pob txha. Qhov no feem ntau yog tsis kav ntev, tab sis nyob rau hauv ib co tsawg tus neeg mob, cov poj niam tej zaum yuav kuj tsim theem ntawm calcium nyob rau hauv cov ntshav, uas yog tsis prokontroliruesh. Yog hais tias qhov no tshwm sim, ces kev kho mob yuav raug tshem tawm tej lub sij hawm.

Tsis tshua muaj, tab sis ntau kev phiv loj heev yog tseem tau. Cov tshuaj yuav ua rau kom txoj kev pheej hmoo ntawm mob cancer ntawm lub myometrium nyob rau hauv cov poj niam nrog lawm. Nce ntshav yog lwm tau kev phiv loj heev. Sib sib zog nqus cov hlab ntsha thrombosis tshwm sim, tab sis tej zaum ib daim ntawm cov ntshav los khov rau ntawd yuav tawg tam sim ntawd thiab nws thiaj li thaiv leeg nyob rau hauv lub ntsws (pulmonary embolism).

Feem ntau yeej tsis "tamoxifen" yog qhov ua rau ntawm tus cwj nrag thiab lub plawv sib cem nyob rau hauv postmenopausal cov poj niam.

Nyob rau hauv lub menopausal raws li txoj cai ntawm cov poj niam "tamoxifen" yuav muaj sib txawv los rau cov pob txha. Nyob rau hauv premenopausal cov poj niam, "tamoxifen" yuav ua rau thinning ntawm cov pob txha, tab sis nyob rau hauv post-menopausal cov poj niam tsub kom cov theem ntawm calcium, tsim nyog rau cov pob txha muaj zog.

Cov kev pab cuam ntawm cov tshuaj no outweigh cov kev txaus ntshai rau yuav luag tag nrho cov poj niam uas hormone-dependent tus mob cancer mis.

Ib yam li ntawd, cov tshuaj yog "Toremifene", uas yog pom zoo rau kev kho mob ntawm metastatic mob cancer mis. Txawm li cas los, qhov no tshuaj yuav tsis ua hauj lwm yog siv los ntawm "tamoxifen", tab sis tsis muaj cov nyhuv.

"Fulvestrant" yog ib cov tshuaj uas blocks thawj estrogen receptor, thiab ces kuj yuav tshem receptor losis tswvyim dabtsi muaj peev xwm. Nws ua raws li ib tug anti-tshuaj thoob plaws hauv lub cev.

"Fulvestrant" yog siv los kho khiav metastatic mob cancer mis, thiab feem ntau siv tom qab lwm yam hormonal tshuaj ( "tamoxifen" thiab aromatase inhibitors) uas nres ua hauj lwm.

Common tshwm sim muaj xws kub flashes, tawm hws hmo ntuj, ntsis xeev siab thiab nkees heev. Raws, nws yuav tsis muaj zog kom cov pob txha (osteoporosis), Yog hais tias muab rau ib tug ntev lub sij hawm.

Qhov no tshuaj tau yeej paub txog kev siv nyob rau hauv postmenopausal cov poj niam uas tsis tau teb rau "tamoxifen" los yog "Toremifene." Nws yog tej zaum kuj siv tau rau nws npaj lub hom phiaj nyob rau hauv premenopausal cov poj niam, feem ntau nyob rau hauv ua ke nrog nrog ib tug luteinizing hormone-tso agonist tig tawm lub zes qe menyuam.

"Raloxifene" siv los ntawm cov poj niam rau kev tiv thaiv thiab kev kho mob ntawm pob txha poob los yog txha tom qab lawm. Nws yuav pab kom muaj zog kom cov pob txha, txo txoj kev pheej hmoo ntawm cov pob txha lov.

"Raloxifene" kuj yuav tiv thaiv tau qhov tshwm sim ntawm tus mob khees xaws mis tom qab lawm. Nws tsis yog cov tshuaj no lawm, tab sis ua zoo li cov tshuaj no nyob rau hauv tej qhov chaw ntawm lub cev, xws li pob txha. Nyob rau hauv lwm qhov chaw ntawm lub cev (mis thiab tsev menyuam), "Raloxifene" ua li ib qho tshuaj blocker. Nws tsis pab ib tug ntau yam ntawm menopausal syndrome. Raloxifene koom mus rau ib tug hauv chav kawm ntawv ntawm cov tshuaj lub npe hu ua xim estrogen receptor modulators-SERMs (estrogenic thiab antiestrogenic yeeb siv tshuaj).

Anti-tshuaj tshuaj thiab kev ua si

Ib co tshuaj lug siv nyob rau hauv bodybuilders rau lawv muaj nqaij.

"Cyclofenil" - yog neanabolichesky / androgenic steroid. Nws ua hauj lwm raws li ib tug anti-tshuaj thiab testosterone raws li ib tug stimulant. "Cyclofenil" yog ib tug heev muaj zog thiab me me tshuaj no, tab sis nws uake tshuaj receptors thiab tiv thaiv thwj toob ntawm tej yam ntuj tso tshuaj receptors. Nyob rau hauv qhov tseeb, nws ua hauj lwm zoo li ntawd hais tias ib co ncaws pob noj cov tshuaj thaum lub sij hawm ib tug steroid kho mob nyob rau hauv thiaj li yuav muaj tsawg theem ntawm cov tshuaj no. Cov - txo tus nqi ntawm cov dej nyob rau hauv lub cev, uas yog tsim rau steroids thiab yuav txo tau nyob rau hauv gynecomastia. Cov kis las muaj ib tug nyuaj sab nrauv, siv xws tshuaj, uas yuav muaj feem raug coj thaum lub sij hawm kev npaj rau ib tug sib txeeb. Bodybuilders, txawm li cas los, siv nws tsawg feem ntau vim hais tias lawv xav ib tug ntau pheej yig 'Nolvadex' thiab 'Proviron. "

Zoo li "Clomid", "Cyclofenil" yog ices rau cov poj niam, raws li nws muaj ib tug zoo feem tsuas yog nyob rau zus tau tej cov tshuaj hormones rau cov txiv neej. Raising lub theem ntawm testosterone tshwm sim los ntawm cov tshuaj no yog tsis txaus los tham txog kev txhim kho radical, tab sis nws yuav muab hwj chim nce, txawm ib tug me me nce nyob rau hauv lub cev hnyav, ib tug tseem ceeb nce nyob rau hauv lub zog thiab ib qho kev nce nyob rau hauv lub lwm tau. Cov kev tshwm sim yog pom tshwj xeeb tshaj yog nyob rau hauv advanced ncaws pob uas muaj me me los yog tsis muaj kev nrog steroids. Siv cov kev tshwm sim ua pom tsuas yog tom qab ib lub lim tiam.

Nyob rau hauv tej rooj plaub, ncaws pob cov menyuam eruptions xws li pob txuv, nce deev tsav thiab kub flushes. Cov tsos mob yog tshwj xeeb tshaj yog indicative pov thawj hais tias tus compound yog ua tau zoo. Tom qab discontinuation ntawm ib co qhia kev nyuaj siab mus ob peb vas thiab ib tug me ntsis txo nyob rau hauv lub dag lub zog. Cov neeg uas coj tus yeeb tshuaj raws li ib tug anti-tshuaj thaum lub sij hawm steroid kho mob, yuav soj ntsuam cov lus rov nyhuv thaum cov nyhuv uas cov neeg sawv cev yog nres.

"Proviron" yog ib tug ntawm cov hiob anabolic androgenic steroids rau lub lag luam. Teb hu ua tus "Mesterolone", nws tseem yog ib tug ntawm cov feem ntau unclaimed cov anabolic steroid cov neeg siv.

Nyob rau ib tug haumxeeb hauv paus Proviron muaj plaub lub ntsiab zog, uas lom zem ntau txiav txim thaum kawg nws ntawm kev txiav txim. Ua ntej ntawm tag nrho cov, nws yog ib tug ntawm cov haib tshaj anabolic steroids, vim hais tias nws yuav tsub tus nqi ntawm circulating free testosterone, uas yog tseem ceeb heev rau anabolic dab bodybuilders. Ib tug yooj yim txoj kev uas yuav saib nws: yog hais tias koj noj anabolic steroids, cov nqaij loj yog nce.

"Proviron®" kuj muaj lub peev xwm mus nrog cov enzyme aromatase, uas yog lub luag hauj lwm rau cov hloov dua siab tshiab ntawm testosterone rau cov tshuaj no. Los ntawm ruaj rau aromatase, "Proviron®" yuav ua tau inhibit txoj kev, li no muab kev tiv thaiv los ntawm phiv los ntawm cov tshuaj no.

On "Mesterolone" kuj muaj ib tug muaj zog sib ze rau cov androgen receptor. Qhov no anabolic steroid uas tsis suppress gonadotropins yog zoo li lwm yam anabolic steroids. Qhov no ua rau nws ua tau rau kom lub zus tau tej cov phev raws li androgens yog tsim nyog rau lub stimulation ntawm spermatogenesis. Qhov no tsis tsuas tsub kom lub xov tooj ntawm cov phev, tab sis kuj pab nws zoo.

Sab los "Proviron" tsis muaj xws li gynecomastia los yog tshaj kua. Qhov no yuav kuj txo txoj kev pheej hmoo ntawm cov ntshav siab txuam nrog kev noj anabolic steroids. Nyob rau hauv qhov tseeb, "Proviron" muaj anti-estrogenic nyhuv los siv ceev xwmphem lub hloov dua siab tshiab ntawm testosterone rau cov tshuaj no, los yog tsawg kawg qeeb tus txheej txheem no.

Qhov saum toj no-hais cov tshuaj tsis txo cov tshuaj no theem, tab sis muaj kev cuam tshuam cov metabolism hauv general.

Cov pab pawg neeg ntawm antiestrogenic tshuaj kuj muaj xws li agonists tso yam gonadotropic cov tshuaj hormones ( "Buserelin" thiab nws cov analogs), megestrol acetate ( "Megeys") "Parlodel" thiab "Dostinex" yog siv raws li cov tshuaj, suspending prolactin secretion. Lawv tus kheej siv nyob rau hauv cov kev kho mob uas tsis yog-muaj kuab.

Kev kho mob ntawm cancer

Nyob rau hauv tas li ntawd mus rau "tamoxifen" Cov nram qab no tshuaj receptor blockers.

Peb cov tshuaj uas tsis txhob zus tau tej cov tshuaj no nyob rau hauv postmenopausal cov poj niam, tau tso cai los kho ob thaum ntxov thiab heev mis mob cancer: "Letrozole" ( "Femara"), "Anastrozole" ( 'Arimidex') thiab "Exemestane" ( "AROMASIN") .

Lub mechanism ntawm qhov kev txiav txim ntawm anti-tshuaj tshuaj nyob rau hauv no pab pawg neeg - lub thaiv cov hlab ntawm lub enzyme (aromatase) nyob rau hauv adipose ntaub so ntswg, uas yog lub luag hauj lwm rau me me ntawm cov tshuaj no nyob rau hauv post-menopausal cov poj niam. Lawv tsis muaj kev cuam tshuam lub zes qe menyuam, yog li tsuas zoo rau cov poj niam uas nws zes qe menyuam tsis ua hauj lwm, tog twg los vim hais tias lawm los yog vim hais tias ntawm tej yam ntawm luteinizing hormone analog. Cov tshuaj noj txhua txhua hnub nyob rau hauv cov ntsiav tshuaj daim ntawv. Lawv ua hauj lwm sib npaug zoo nyob rau hauv cov kev kho mob ntawm oncological dab nyob rau hauv lub mis thiab prostate.

Tej zaum lub mis mob cancer kho mob yuav tsum tau kev kho mob ntawm zes qe menyuam. Qhov no yuav ua tau nrog cov tshuaj analogues ntawm luteinizing hormone-tso lawm (LHRH), piv txwv li, "Goserelin" ( "Zoladex") los yog "leuprolide" ( "Lyupron"). Cov tshuaj thaiv lub teeb liab uas xa mus rau lub cev lub zes qe menyuam yuav tsim estrogen lawv. Lawv yuav siv tau nyob ib leeg los yog nrog "tamoxifen", aromatase inhibitors, "Fulvestrant" rau hormonal kho nyob rau hauv premenopausal cov poj niam.