"Amoxiclav 625": cov lus qhia rau kev siv, tiag tiag counterparts

Ntawm cov antimicrobial cov neeg ua hauj nyob rau hauv cov kev npaj "Amoxiclav 625" neeg mob testimonials thiab cov tub txawg hauv lub feem ntau revealing. Cov tshuaj no yog hais tias yuav lub feem ntau ntau cov tshuaj tua kab thiab yog li ntawd yuav tsum tau txais wider paub. Vim rau ntau yam kev ua ub no, kev ruaj ntseg ntawm cov me nyuam thiab lactating cov poj niam, "Amoxicillin-clavulanate" yuav luag tag npog ib tug kheej ntawm empirical txoj kev kho pw ua pa thiab mob txeeb kab mob.

Tso Highlights thiab analogues

Kev npaj "Amoksiklav 625" ua los ntawm Slovenian Lek thiab positioned raws li yeeb tshuaj active tshuaj yog aminopenicillin amoxicillin thiab clavulanic acid. Tus thawj plays lub luag hauj lwm ntawm cov tshuaj tua kab thiab acid tiv thaiv kab mob beta-lactamases. Raws li ib feem ntawm "Amoksiklav 625 mg" tshuaj ntsiav tshuaj comprise 500 mg ntawm tshuaj tua kab mob, thiab 125 mg ntawm clavulanate koom haum pab.

Cov kev npaj muaj tus nquag tshuaj amoxycillin ua nyob rau hauv ib tug ntau yam ntawm cov npe. Qhov tseem zoo analogues yog cov nram qab no muaj kev tiv thaiv aminopenicillin "Amoklav", "Augmentin", "Flemoklav", "Amklav", "Farmentin", "Amoksikar Plus", "txhawb pab", "Medoklav". Tseem muaj kev tiv thaiv zoo penicillins, uas yog analogues ntawm cov chav kawm ntawv "Amoksiklava": "Amoxicillin", "Amoksikar", "Amosin", "Hikontsil" thiab lwm tus neeg. Lawv ua hauj lwm zoo yog xav tau txog tib.

Qhov tseeb ntawm cov tshuaj

Nyob rau hauv kev npaj "Amoxiclav 625" cov lus los ntawm cov kws txawj yog heev ntshiab. Qhov no zoo medicament, yog ib lub xwb qhov ncauj antimicrobial tshuaj uas yog yus los tsis muaj kev phiv. Vim li no nws yog siv nyob rau hauv tag nrho cov mob nyob rau hauv uas amoxicillin yog tsim nyog. Thiab "Amoxiclav" yog tus neeg sawv cev ntawm lub neej coj tshuaj. Nws yog kev tiv thaiv clavulanic acid los ntawm penicillinase, ib qho enzyme uas txav cov lactam lub nplhaib ntawm cov tshuaj tua kab mob. Tsaug rau kev tiv thaiv ntawm "Amoxiclav" ua ntau yam kom nquag plias txoj kev lub microbial hlwb.

zaj lus tim khawv

Txuas mus rau lub tshuaj "Amoxiclav 625" phau ntawv muaj cov lus qhia rau kis kab mob, cov kev kho mob uas yog tau tso cai rau siv ib qho tshuaj tua kab mob. Qhov no feem ntau tsim pa, hnyuv, genitourinary kab mob ntawm me me los yog muaj mob loj tsawv heev. Nyob rau hauv yam ntaub ntawv uas tsim nyog monotherapy, whereas ntsis thiab mob yuav tsum tau kho nyob rau hauv lub mus pw pawg ntseeg ntawm tshuaj tua kab mob thaum lawv tseem. Nyob rau hauv kev, indications rau kev siv "Amoxiclav 625 mg ntawm" kev npaj daim ntawv qhia no qhia txog raws li nram no:

• kab mob ntawm lub Upper pa kabmob (mob thiab mob ntaub ntawv ntawm tonsillitis, pharyngitis, sinusitis, otitis xov xwm);
• kis kab mob ntawm lub sab ua pa ib ntsuj av tau kab mob (mob thiab ntev ntaub ntawv ntawm bronchitis, mob ntsws);
• kab mob cov kab mob ntawm lub urogenital system (pyelonephritis, urethritis, cystitis, oophoritis, pelvic o, endometritis, gonorrhea, chancroid);
• mob osteomyelitis;
• daim tawv nqaij kab mob, kis kab mob tsiaj tom, qhov txhab colonization by kab mob;
• periodontitis.

Rau cov neeg mob, cov thawj qhov chaw ntawm cov ntaub ntawv hais txog cov "Amoxiclav" npaj - phau ntawv qhia. 625 mg ntawm cov tshuaj yeeb tshuaj, xws triplicate rau ib tug neeg laus, yuav zoo kho cov kab mob ntawm lub pa system tshwm sim los ntawm gram-zoo advantageously muaj. Thiab nyob rau Ari kev kho mob lub sij hawm yog feem ntau yog 5-7 hnub.

Contraindications

Cov tshuaj txoj kev nyab xeeb cov ntaub ntawv thiab tsis muaj toxicity chav kawm ntawv ntawm penicillin tsis cais hauv lub xub ntiag ntawm contraindications.

Lawv muaj ib tug me ntsis tshuaj. Lawv yog hais txog tog twg los muaj cov concomitant kab mob, kev tsis haum cov tshuaj tiv thaiv los yog physiological lub xeev ntawm tus kab mob. Contraindications muaj xws li:

• muaj hais txog ntawm qhov tshwm sim ntawm cholestatic daj ntseg, nce aminotransferase kev ua si los yog kev loj hlob ntawm tus kab mob siab tshwm sim los ntawm cov ua ntej lawm daim ntawv thov "Amoksiklava", nws analogs los yog cov neeg sawv cev ntawm cov pab pawg neeg ntawm penicillins;
• hepatic insufficiency, lymphatic leukemia, mononucleosis vim ntsuas ntawm tus xov tooj thiab qhov ntawm cov kev phiv;
• tsis haum sensitization mus rau yeeb tshuaj los yog nws cov yam;
• indications ntawm lub rov tshwm sim tam sim ntawd yam tsis haum tshuaj loj thaum noj lwm yam beta-lactam antimicrobial agents;
• txheeb ze lub sij hawm contraindications: cev xeeb tub nyob rau hauv lub thib 3 peb lub hlis ntawm lactation.

Cov kev pheej hmoo ntawm kev tsim kev ua xua

Yog hais tias tus neeg mob lub keeb kwm muaj yog ib tug siv rau lub zos hom kev tsis haum tshuaj, "Amoxiclav" tsis muab. Yog hais tias tsim anaphylaxis los yog angioedema nyob rau hauv cov lus teb rau tau txais lwm cov beta-lactam antimicrobial agents, cov "Amoxicillin-clavulanate" yuav tsum tsis tau txais. Ces cov tshuaj uas koj xaiv yog tus neeg sawv cev ntawm ib tug xov tooj ntawm macrolides nyob rau hauv ib tug loj tsawv cov hoob kawm, los yog ib tug fluoroquinolone.

dosing kiag

Tus nqi ntawm cov tshuaj "Amoksiklav 625 mg," uas yog yuav tsum tau rau cov kev kho mob nyob rau hauv lub hnub nyoog thiab nyhav ntawm tus neeg mob. Ua pa kab mob rationally muab li 2 grams rau cov neeg laus thiab 1.3 grams ntawm cov hluas. Lub "Amoxiclav" nyob rau hauv ib koob tshuaj 625 mg yog tus tsuas yog cov tub ntxhais hluas thiab neeg laus cov tshuaj. Rau cov me nyuam nyob rau hauv 12 lub xyoos ntawm hnub nyoog, muaj cov tshuaj txo koob tshuaj.

Standard ntau npaum rau ib tug tib neeg uas 40 kg thiab 12 xyoos ntawm hnub nyoog yog 625 mg ib hnub ob zaug. Cov neeg laus muaj hnub nyoog 18 xyoo muab 625 mg peb zaug ib hnub twg. Qhov no yog txaus rau kev kho mob ntawm loj tsawv thiab lub teeb, uas yog, pw kab mob ntawm daim tawv nqaij, ua pa, urogenital system. Rau hauv loj heev mob muab 1000 mg (875 mg ntawm amoxycillin thiab clavulanate 125) ob zaug ib hnub twg. Pub txoj hlua peb daim ntawv thov ntawm 1000 mg.

sab nyhuv

Txawm tias txaus breadth ntawm tshuaj txiav txim, muaj ib tug xov tooj ntawm cov kev phiv. Lawv yog txuam nrog rau hauv zos mob ntawm plab hnyuv thiab pais plab zog, raws li zoo raws li vim intoxication lwj cov khoom ntawm cov kab mob hlwb, raws li tshuaj tua kab mob bactericidal nyhuv.

Qhov feem ntau heev (1-10%) yog cov mob ntawm xeev siab, ntuav los yog zawv plab tshwm sim tom qab daim ntawv thov ntawm cov antimicrobial neeg sawv cev. Thiab lawv yuav tshwm sim 2-4 hnub tom qab nkag. Ho tsub kom qhov tshwm sim ntawm dyspepsia twb uas twb muaj lawm ntxaug nyob rau hauv plob tsis so tswj tsis tau, thiab ib co nrog cov kab mob: pancreatitis nrog excretory insufficiency, enteritis mob tom qab resection ntawm lub plab los sis tso quav, mob plab.

Cov pab pawg neeg ntawm tsis ntau teeb meem (0,001-0,0001%) yog siab mob: ntau zog transaminases thiab npiv zas ntawm hepatocyte cytolysis, cholestasis thiab daj ntseg, leukopenia. Lub zaus angioedema, urticaria thiab anaphylaxis yog unspecified. Yog vim li cas rau qhov no yog qhov gradual nce nyob rau hauv lub xov tooj ntawm kev tsis haum tshuaj vim mus rau thaum ntxov sensitization ntawm cov me nyuam.

Tom qab ntawd, nws yuav tau ua rau ib tug txo nyob rau hauv qhov tseem ceeb ntawm tshuaj yeeb tshuaj "Amoxiclav". Cov lus qhia rau kev siv 625-mg ntsiav tshuaj yog tsis tau txwv tsis pub txoj kev siv cov niam. Txawm li cas los, qhov no tej zaum sai sai tshwm sim. Ces koj yuav tsum tau saib rau ib cov tshuaj tshiab ntawm amino nrog zoo xws li cov efficiency. Lawm, hais tias tus tshiab tshuaj tshuaj tau tsim thiab kuaj, tab sis nws siv kom txog thaum kev lag kev luam disadvantageous, vim hais tias "Amoxiclav" raws li cov kev cai ntawm clinicians.

Txais tos thaum lub sij hawm cev xeeb tub thiab lactation

Raws li cov FDA ntaub ntawv, "Amoxiclav" tsis muaj ib tug teratogenic nyhuv. Qhov no xaus twb mus txog tom qab kev tshawb fawb nyob rau hauv cov tsiaj, vim hais tias tag nrho cov analogues ntawm cov tshuaj muaj nyob rau hauv Qeb B los ntawm FDA (TEB CHAWS USA). Txawm li cas los, vim rau muaj kuab kev ntshai ntawm ntsuas toxicosis "Amoxiclav 625" thaum lub sij hawm cev xeeb tub yuav luag tsis muab nyob rau hauv thawj peb lub hlis. Nyob rau hauv II thiab III trimesters ntawm nws txais tos yog tso cai.

Aminopenicillin nyob rau hauv txoj lw nqi mus rau hauv niam cov kua mis, uas poob nyob rau hauv lub mob huam ntawm tus me nyuam mos. Txawm li cas los, tseem ceeb ua txhaum nyob rau hauv nws lub cev, nws tsis ua, vim hais tias ntawm yog dab tsi "Amoxiclav 625" yuav tsis rho thaum lub sij hawm lactation. Cov xwb yog tus neeg mob ntawm kev tsis haum tshuaj rau tus me nyuam los yog vulvovaginal txheej week los yog cov hnyuv, ua nyob rau hauv daim ntawv thov ntawm "Amoxicillin". Ces nws yuav tsum tau tog twg los lub abolition ntawm leej niam tau txais ib tug antimicrobial neeg sawv cev, los yog - thaum mucosal Candidiasis - tsis pub niam mis.

tshuaj muaj kev ruaj ntseg feature

Ntsiav tshuaj "Amoxiclav 625" yog tubntxhais sab spectrum ntawm tshuaj txiav txim, yog li tsis txhob raug tshuaj lom. Tsis tas li ntawd, nws twb tsis muaj central los, vim hais tias ntawm yog dab tsi yuav tsum tau muab rau cov neeg mob uas lub ntsiab ntawm lub tsheb los yog lwm yam mus mechanisms. Nws tsis ua rau kev ua txhaum ntawm lub cim xeeb, nco qab, mloog, los yog kev xav.

Txawm li cas los, muaj ib tug overdose syndrome tshuaj. Xws li mob yog tsis tshua muaj, thiab tshwm sim heev dua lwm yam nyob rau hauv tus neeg mob undue ib koob tshuaj 5 los yog ntau tshaj grams ntawm cov tshuaj. Cov tsos mob yog cov nram qab no cov yam ntxwv: raws plab mob txuam nrog rau heev ntawm mob plab, tsam plab, raws plab, xeev siab thiab tej zaum ntuav.

Muaj mob crystalluria, mating nrog qhov tsawg ntawm cov amoxicillin, tej zaum ua rau txoj kev loj hlob ntawm lub raum tsis ua hauj lwm. Txawm li cas los, qhov no tshwm sim yuav tshwm sim thaum tau txais ib tug kho ntau npaum ntawm cov tshuaj. Txhais tau hais tias ib tug nefroprotektsiya kev kho mob thiab lim ntshav, tso cai rau kom tshem tawm los ntawm cov ntshav ntawm amoxicillin thiab clavulanic acid.

precautionary ntsuas

Cov neeg mob uas lymphatic leukemia, los yog kis mononucleosis tshuaj "Amoksiklav 625", analogs thiab Generics tsis tso tawm vim lub high yuav ua rau muaj morbilliform pob. Thiab vim hais tias ntawm lub txo nyob rau hauv cov hauj lwm zoo ntawm qhov ncauj contraceptives thaum lub sij hawm kev kho mob "Amoxicillin" uas yuav tsum tau los txuam rau kev tiv thaiv tiv thaiv pliaj cev xeeb tub barrier txoj kev (looj).

Nrog rau txoj kev loj hlob ntawm raws plab thaum lub sij hawm siv "Amoksiklava" yuav tsum tau tshem tawm ntawm lub tshuaj tua kab mob thiab kev kho mob ntawm plab (pseudomembranous los yog hemorrhagic). Nyob rau hauv no qhov teeb meem, daim ntawv thov yog inadmissible "Loperamide". Tsis tas li ntawd, ntev-lub sij hawm daim ntawv thov "Amoksiklava" txhawb rau txoj kev loj hlob ntawm ntau microbial zos tiv thaiv kab mob rau antimicrobials. Lawv muaj peev xwm ua rau mob ntawm tus kab mob no.

Paub cov tshuaj cov kev sib tshuam

Urikozostatichesky tshuaj "allopurinol" nyob rau hauv lub txais tos nrog "Amoksiklava" tsub kom qhov uas yuav ntawm daim tawv nqaij ua pob ua xyua. Daim ntawv thov urikozuricheskogo txhais tau tias "Probenecid", "oxyphenbutazone," "phenylbutazone", "sulfinpyrazone" los yog acetylsalicylic acid thiaj li qee ntawm aminopenicillin (tab sis tsis clavulanic acid), vim hais tias ntawm cov uas ib nyuag tsub kom lub concentration ntawm tshuaj tua kab mob nyob rau hauv cov ntshav ntshiab thiab cas sim haum nws cov teebmeem.

Thaum lawv tseem tshuaj "Amoksiklav 625 mg" nrog bacteriostatic antimicrobials irrational vim hais tias ntawm lawv cov kev sib nrig sib hluav efficiency. Lwm yam npaj muaj amoxicillin, los yog yuav tsum tau chav nrog bacteriostatic: chloramphenicol, macrolides, tetracyclines thiab sulfonamides. Thaum lawv tseem nrog bactericidal tshuaj tua kab mob ua rau yus kev sib nrig sib nce antimicrobial kev ua si.

Thov "Amoxiclav" thaum lub sij hawm txoj kev kho, qhov ncauj contraceptives lub sij hawm vim muaj kev pheej hmoo uas muaj zog prothrombin lub sij hawm thiab thrombosis. Nyob rau hauv no contraceptive hauj lwm zoo yog significantly txo. Lwm yam sab spectrum tshuaj tua kab mob kuj kho cov nyhuv ntawm kev txo cov hauj lwm zoo ntawm qhov ncauj contraceptive npaj.

Txoj kev siv "Amoksiklava" oportunisticheskih los kho kab mob uas tshwm sim taus rau ib tug tom qab ntawm methotrexate txoj kev kho, ho tsub kom lub toxicity ntawm lub yav tas. Qhov no yuav tsub kom qhov yuav tshwm ntawm thrombocytopenia, leukopenia, daim tawv nqaij ulcers, hnyuv ulcers thiab erosions. Ces nws yog pom zoo kom muab aminopenicillin siv macrolides, ntxiv ntxiv kev kho mob nrog methotrexate.

Raws li cov kev broad-spectrum tshuaj tua kab mob, "Amoxiclav" tsub kom lub efficiency ntawm indirect anticoagulants. Therapy "warfarin" vim hais tias ntawm kev tsim txom ntawm antimicrobial agents los ntawm cov kab mob uas ua ke vitamin K ua rau ib tug txo nyob rau hauv prothrombin index thiab muaj zog INR. Cov no ib tug ntau dua uas yuav muaj los ntshav.

Yam ntawm lub neej coj antimicrobial txoj kev kho

Tshuaj "Amoxiclav 625" thiab nws cov generic counterparts muaj lub peev xwm yuav ua tau kom qhov yuav raws plab, yog siv nrog rau lwm cov antimicrobial agents. Tej chav kawm ntawm tshuaj tua kab mob nrog amoxicillin ho ntau yuav ua rau raws plab, uas yuav tsis raug kho nrog kev pab los ntawm oppressive peristalsis. Tej kev npaj no yog "Loperamide" thiab nws cov analogues, txhob nyob rau hauv cov kab mob raws plab. Nyob rau hauv cov ntaub ntawv no, raws plab tshwm sim los ntawm kev siv ntawm "Amoksiklava" yuav tsum tau kho nrog tshuaj tua kab mob.